Literature DB >> 35750763

Tailored concept for the plastic closure of pelvic defects resulting from extralevator abdominoperineal excision (ELAPE) or pelvic exenteration.

Julia Jackisch1, Thomas Jackisch1, Joerg Roessler2, Anja Sims1, Holger Nitzsche1, Pia Mann1, Sören Torge Mees1, Sigmar Stelzner3,4.   

Abstract

PURPOSE: No standard exists for reconstruction after extralevator abdominoperineal excision (ELAPE) and pelvic exenteration. We propose a tailored concept with the use of bilateral gluteal V-Y advancement flaps in non-extended ELAPE and with vertical myocutaneous rectus abdominis muscle (VRAM) flaps in extended procedures. This retrospective study analyzes the feasibility of this concept. PATIENTS AND METHODS: We retrieved all consecutive patients after ELAPE or pelvic exenteration for rectal, anal, or vulva cancer with flap repair from a prospective database. Perineal wound complications were defined as the primary endpoint. Outcomes for the two different flap reconstructions were analyzed.
RESULTS: From 2005 to 2021, we identified 107 patients who met the study criteria. Four patients underwent exenteration with VRAM flap repair after previous V-Y flap fashioning. Therefore, we report on 75 V-Y and 36 VRAM flaps. The V-Y group contained more rectal carcinomas, and the VRAM group exhibited more patients with recurrent cancer, more multivisceral resections, and longer operation times. Perineal wound complications occurred in 21.3% in the V-Y group and in 36.1% in the VRAM group (p = 0.097). Adjusted odds ratio for perineal wound complication was not significantly different for the two flap types.
CONCLUSION: Concerning perineal wound complications, our concept yields favorable results for V-Y flap closure indicating that this less invasive approach is sufficient for non-extended ELAPE. Advantages are a shorter operation time, less donor site morbidity, and the option of a second repair. VRAM flaps were reserved for larger wounds after pelvic exenteration or vaginal repair.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Extralevator abdominoperineal excision; Gluteal V–Y advancement flap; Perineal wound closure; Perineal wound complications; Vertical rectus abdominis myocutaneous flap

Mesh:

Substances:

Year:  2022        PMID: 35750763     DOI: 10.1007/s00384-022-04196-6

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.796


  47 in total

1.  Primary perineal wound closure after preoperative radiotherapy and abdominoperineal resection has a high incidence of wound failure.

Authors:  Kelli M Bullard; Judith L Trudel; Nancy N Baxter; David A Rothenberger
Journal:  Dis Colon Rectum       Date:  2005-03       Impact factor: 4.585

2.  Long-term outcome of extralevator abdominoperineal excision (ELAPE) for low rectal cancer.

Authors:  Sigmar Stelzner; Gunter Hellmich; Anja Sims; Thomas Kittner; Eric Puffer; Joerg Zimmer; Dorothea Bleyl; Helmut Witzigmann
Journal:  Int J Colorectal Dis       Date:  2016-09-09       Impact factor: 2.571

3.  A hundred patients with vertical rectus abdominis myocutaneous (VRAM) flap for pelvic reconstruction after total pelvic exenteration.

Authors:  R E Horch; W Hohenberger; A Eweida; U Kneser; K Weber; A Arkudas; S Merkel; J Göhl; J P Beier
Journal:  Int J Colorectal Dis       Date:  2014-04-22       Impact factor: 2.571

4.  Primary vs myocutaneous flap closure of perineal defects following abdominoperineal resection for colorectal disease: a systematic review and meta-analysis.

Authors:  X Y Yang; M T Wei; X T Yang; Y Z He; Y Hao; X B Zhang; X B Deng; Z Q Wang; Z Q Zhou
Journal:  Colorectal Dis       Date:  2019-01-11       Impact factor: 3.788

Review 5.  Perineal wound healing after abdominoperineal resection for rectal cancer: a systematic review and meta-analysis.

Authors:  Gijsbert D Musters; Christianne J Buskens; Willem A Bemelman; Pieter J Tanis
Journal:  Dis Colon Rectum       Date:  2014-09       Impact factor: 4.585

6.  Local control and survival after extralevator abdominoperineal excision for locally advanced or low rectal cancer.

Authors:  G Palmer; C Anderin; A Martling; T Holm
Journal:  Colorectal Dis       Date:  2014-07       Impact factor: 3.788

7.  Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer.

Authors:  T Holm; A Ljung; T Häggmark; G Jurell; J Lagergren
Journal:  Br J Surg       Date:  2007-02       Impact factor: 6.939

8.  Single centre experience of bilateral gracilis flap perineal reconstruction following extra-levator abdominoperineal excision.

Authors:  J A J Coelho; F D McDermott; O Cameron; N J Smart; A M Watts; I R Daniels
Journal:  Colorectal Dis       Date:  2019-05-17       Impact factor: 3.788

9.  Dynamic article: Vaginal and perineal reconstruction using rectus abdominis myocutaneous flap in surgery for locally advanced rectum carcinoma and locally recurrent rectum carcinoma.

Authors:  Fabian A Holman; Ingrid S Martijnse; Marjan J Traa; Dorry Boll; Grard A Nieuwenhuijzen; Ignace H de Hingh; Harm J Rutten
Journal:  Dis Colon Rectum       Date:  2013-02       Impact factor: 4.585

10.  Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey.

Authors:  Daniel Dindo; Nicolas Demartines; Pierre-Alain Clavien
Journal:  Ann Surg       Date:  2004-08       Impact factor: 12.969

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