Literature DB >> 35743375

One-Stage Coverage of Leg Region Defects with STSG Combined with VAC Dressing Improves Early Patient Mobilisation and Graft Take: A Comparative Study.

Gianluca Sapino1, Loise Lanz1, Aurore Roesti2, David Guillier3, Sebastien Deglise2, Giorgio De Santis4, Wassim Raffoul1, Pietro di Summa1.   

Abstract

Lower limb skin defects are very common and can result from a wide range of aetiologies. Split thickness skin graft (STSG) is a widely used method to address these problems. The role of postoperative dressing is primary as it permits one to apply a uniform pressure over the grafted area and promote adherence. Focusing on lower limb reconstruction, our clinical study compares the application of V.A.C. (Vacuum Assisted Closure) Therapy vs. conventional dressing in the immediate postoperative period following skin grafting. We included in the study all patients who received skin grafts on the leg region between January 2015 and December 2018, despite the aetiology of the defect. Only reconstructions with complete preoperative and postoperative follow-up data were included in the study. Patients were divided into two groups depending on if they received a traditional compressive dressing or a VAC dressing in the immediate postoperative period. We could retain 92 patients, 23 in the No VAC group and 69 in the VAC group. The patients included in the VAC group showed a statistically significant higher rate of graft take together with a lower immobilisation time (p < 0.05). Moreover, a lower rate of postoperative infection was recorded in the VAC group. This study represents the largest in the literature to report in detail surgical outcomes comparing the use of VAC therapy vs. conventional dressing after STSG in the postoperative management of lower limb reconstruction using skin grafts. VAC therapy was used to secure the grafts in the leg region, increasing the early graft take rate while at the same time improving patient mobilisation.

Entities:  

Keywords:  leg ulcer; skin graft; vac therapy; wound healing

Year:  2022        PMID: 35743375      PMCID: PMC9224921          DOI: 10.3390/jcm11123305

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.964


  24 in total

1.  Vacuum-assisted closure used for healing chronic wounds and skin grafts in the lower extremities.

Authors:  Stanley N Carson; Karen Overall; Stephanie Lee-Jahshan; Eric Travis
Journal:  Ostomy Wound Manage       Date:  2004-03       Impact factor: 2.629

2.  Vacuum-assisted closure: microdeformations of wounds and cell proliferation.

Authors:  Vishal Saxena; Chao-Wei Hwang; Sui Huang; Quentin Eichbaum; Donald Ingber; Dennis P Orgill
Journal:  Plast Reconstr Surg       Date:  2004-10       Impact factor: 4.730

3.  Complex lower extremity wounds treated with skin grafts and NPWT: a retrospective review.

Authors:  R E Ross; P Aflaki; C Gendics; J C Lantis Ii
Journal:  J Wound Care       Date:  2011-10       Impact factor: 2.072

4.  ALT flap with vascularized fascia lata for one-stage functional patellar tendon reconstruction.

Authors:  G Sapino; P Zaugg; S Cherix; O Borens; S J Lo; W Raffoul; P G di Summa
Journal:  J Plast Reconstr Aesthet Surg       Date:  2018-11-23       Impact factor: 2.740

5.  Retrospective evaluation of clinical outcomes in subjects with split-thickness skin graft: comparing V.A.C.® therapy and conventional therapy in foot and ankle reconstructive surgeries.

Authors:  Peter A Blume; Jonathan J Key; Pratapji Thakor; Sejal Thakor; Bauer Sumpio
Journal:  Int Wound J       Date:  2010-09-06       Impact factor: 3.315

6.  Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients.

Authors:  A Körber; T Franckson; S Grabbe; J Dissemond
Journal:  Dermatology       Date:  2008-01-17       Impact factor: 5.366

Review 7.  Skin Graft Techniques.

Authors:  Arshad A Khan; Isra M Khan; Phi P Nguyen; Erwin Lo; Hassan Chahadeh; Mathew Cerniglia; James A Noriega
Journal:  Clin Podiatr Med Surg       Date:  2020-10       Impact factor: 1.231

8.  A prospective, blinded, randomized, controlled clinical trial of topical negative pressure use in skin grafting.

Authors:  Elias Moisidis; Tim Heath; Catherine Boorer; Kevin Ho; Anand K Deva
Journal:  Plast Reconstr Surg       Date:  2004-09-15       Impact factor: 4.730

Review 9.  The efficacy of negative pressure wound therapy in the management of lower extremity trauma: review of clinical evidence.

Authors:  N K Kanakaris; C Thanasas; N Keramaris; G Kontakis; Mark S Granick; P V Giannoudis
Journal:  Injury       Date:  2007-11-28       Impact factor: 2.586

10.  An Alternative Treatment Strategy for Complicated Chronic Wounds: Negative Pressure Therapy over Mesh Skin Graft.

Authors:  Michele Maruccia; Maria G Onesti; Valentina Sorvillo; Antonio Albano; Luca A Dessy; Bruno Carlesimo; Mauro Tarallo; Marco Marcasciano; Giuseppe Giudice; Emanuele Cigna; Diego Ribuffo
Journal:  Biomed Res Int       Date:  2017-02-19       Impact factor: 3.411

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  1 in total

1.  Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects.

Authors:  Dinko Martinovic; Slaven Lupi-Ferandin; Daria Tokic; Mislav Usljebrka; Andrija Rados; Ante Pojatina; Sanja Kadic; Ema Puizina; Ante Mihovilovic; Marko Kumric; Marino Vilovic; Dario Leskur; Josko Bozic
Journal:  J Clin Med       Date:  2022-07-31       Impact factor: 4.964

  1 in total

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