| Literature DB >> 35739476 |
Johanna M Joensuu1,2, Hannu Saarijärvi3, Hanna Rouhe4, Mika Gissler5,6,7, Veli-Matti Ulander4, Seppo Heinonen4, Paulus Torkki8, Tomi S Mikkola4,9.
Abstract
BACKGROUND: Childbirth experience has been shown to depend on the mode of delivery. However, it is unclear how labour induction influences the childbirth experience in different modes of delivery. Thus, we assessed the childbirth experience among mothers with spontaneous and induced labours.Entities:
Keywords: Delivery method; Giving birth; Induced labour; Maternal experience; Maternity; Pregnancy
Mesh:
Year: 2022 PMID: 35739476 PMCID: PMC9229460 DOI: 10.1186/s12884-022-04830-9
Source DB: PubMed Journal: BMC Pregnancy Childbirth ISSN: 1471-2393 Impact factor: 3.105
Fig. 1Data inclusion criteria and sample size
The characteristics of spontaneous and induced labour groups for primiparas and multiparas
| Primiparas | Multiparas | ||||||
|---|---|---|---|---|---|---|---|
| Spontaneous | Induced | Spontaneous ( | Induced | ||||
| Mode of delivery | Mode of delivery | <0.001 | <0.001 | ||||
| Vaginal | 70.7% | 54.7% | 91.0% | 83.7% | |||
| Instrumental | 18.3% | 18.9% | 4.3% | 6.3% | |||
| Urgent CS | 10.0% | 25.1% | 4.3% | 9.0% | |||
| Emergency CS | 0.9% | 1.3% | 0.4% | 1.0% | |||
| Maternal characteristics | Maternal age ≥30 | 48.3% | 54.7% | <0.001 | 70.8% | 71.6% | 0.099 |
| BMI before pregnancy ≥30 | 6.6% | 14.4% | <0.001 | 9.7% | 21.0% | <0.001 | |
| Gestational age ≥42 weeks | 2.8% | 23.6% | <0.001 | 1.6% | 15.3% | <0.001 | |
| Prior caesarean section | 13.2% | 22.5% | <0.001 | ||||
| Delivery characteristics | Partner support | 79.1% | 77.7% | 0.002 | 91.9% | 90.6% | <0.001 |
| Use of epidural anesthesia | 75.4% | 75.6% | 0.673 | 57.4% | 70.3% | <0.001 | |
| Prolonged labour | 11.7% | 18.4% | <0.001 | 4.1% | 7.1% | <0.001 | |
| Birth weight | <0.001 | <0.001 | |||||
| <3400g | 44.8% | 40.1% | 31.2% | 29.0% | |||
| 3400-3799 g | 34.1% | 31.2% | 35.4% | 30.4% | |||
| 3800-4199g | 16.2% | 20.6% | 23.9% | 26.7% | |||
| ≥4200g | 4.9% | 8.1% | 9.5% | 13.9% | |||
*Chi-Square test used to detect significant differences between the distributions of spontaneous and induced labors
The model coefficients and p-values for both primiparas and multiparas
| Primiparas | Multiparas | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Model1 | Model2 | Model3 | Model1 | Model2 | Model3 | ||||||||
| Parameter | B | Sig. | B | Sig. | B | Sig. | B | Sig. | B | Sig. | B | Sig. | |
| Intercept | 8.26 | 0.000 | 8.78 | 0.000 | 8.77 | 0.000 | 8.72 | 0.000 | 8.88 | 0.000 | 8.88 | 0.000 | |
| Onset of labour | Induction | -0.34 | 0.000 | -0.28 | 0.000 | -0.20 | 0.000 | -0.25 | 0.000 | -0.22 | 0.000 | -0.19 | 0.000 |
| Spontaneousa | 0* | 0* | 0* | 0* | 0* | 0* | |||||||
| Mode of delivery | Emergency CS | -1.32 | 0.000 | -1.52 | 0.000 | -1.50 | 0.000 | -1.88 | 0.000 | -1.90 | 0.000 | -1.70 | 0.000 |
| Urgent CS | -0.97 | 0.000 | -0.93 | 0.000 | -0.80 | 0.000 | -1.03 | 0.000 | -0.85 | 0.000 | -0.73 | 0.000 | |
| Instrumental delivery | -0.75 | 0.000 | -0.57 | 0.000 | -0.54 | 0.000 | -0.91 | 0.000 | -0.74 | 0.000 | -0.74 | 0.000 | |
| Vaginal deliverya | 0* | 0* | 0* | 0* | 0* | 0* | |||||||
| Interaction terms | Induction * Emergency CS | -0.11 | 0.528 | -0.51 | 0.004 | ||||||||
| Induction*Urgent CS | -0.32 | 0.000 | -0.34 | 0.000 | |||||||||
| Induction* Intrumental delivery | -0.12 | 0.016 | 0.01 | 0.875 | |||||||||
| Confounding variables | Age of parturient ≥30 years | -0.10 | 0.000 | -0.10 | 0.000 | -0.03 | 0.021 | -0.03 | 0.018 | ||||
| BMI before pregnancy ≥30 | -0.03 | 0.324 | -0.03 | 0.353 | -0.03 | 0.072 | -0.03 | 0.082 | |||||
| Partner support | 0.09 | 0.000 | 0.09 | 0.000 | 0.02 | 0.475 | 0.01 | 0.510 | |||||
| Gestational age | -0.04 | 0.216 | -0.03 | 0.312 | 0.04 | 0.142 | 0.05 | 0.113 | |||||
| Use of epidural anesthesia | -0.35 | 0.000 | -0.35 | 0.000 | -0.06 | 0.000 | -0.06 | 0.000 | |||||
| Prolonged labour | -0.37 | 0.000 | -0.37 | 0.000 | -0.47 | 0.000 | -0.46 | 0.000 | |||||
| Fear of childbirth | -0.41 | 0.000 | -0.42 | 0.000 | -0.22 | 0.000 | -0.22 | 0.000 | |||||
| Birth weight (categories) | -0.08 | 0.000 | -0.08 | 0.000 | -0.03 | 0.000 | -0.03 | 0.000 | |||||
| Prior CS | -0.06 | 0.001 | -0.06 | 0.001 | |||||||||
a Reference group
Fig. 2The adjusted means of VAS with 95% confidence intervals for spontaneous and induced labours in each mode of delivery (corresponding data in a numerical Table 6 is available in a supplementary file)
Childbirths with low VAS (≤5) in each mode of delivery for induced and spontaneous labour groups and corresponding odd ratio estimates with 95% confidence intervals
| Spontaneous labour | Induced labour | |||||
|---|---|---|---|---|---|---|
| Vaginal delivery (both) | 1183 | 5.3 | 503 | 7.9 | 1.54 | 1.38 to 1.71 |
| Instrumental delivery | 774 | 13.3 | 444 | 20.1 | 1.64 | 1.44 to 1.87 |
| Urgent CS | 511 | 16.1 | 721 | 24.6 | 1.70 | 1.50 to 1.93 |
| Emergency CS | 75 | 25.0 | 41 | 26.5 | 1.08 | 0.69 to 1.68 |
| Vaginal delivery (both) | 895 | 2.4 | 369 | 4.1 | 1.74 | 1.54 to 1.97 |
| Instrumental delivery | 185 | 10.5 | 97 | 14.3 | 1.43 | 1.10 to 1.87 |
| Urgent CS | 198 | 11.2 | 176 | 18.2 | 1.77 | 1.42 to 2.21 |
| Emergency CS | 37 | 24.3 | 36 | 35.3 | 1.70 | 0.98 to 2.94 |
The percentage distributions of actual mode of deliveries following spontaneous and induced labours. The corresponding relative risk with 95 % confidence interval for belonging to each group when labour was induced
| Spontaneous labour | Induced labour | |||||
|---|---|---|---|---|---|---|
| Vaginal delivery (both) | 22 428 | 70.7 | 6 382 | 54.7 | 0.77 | 0.76 to 0.79 |
| Instrumental delivery | 5 819 | 18.3 | 2 206 | 18.9 | 1.03 | 0.99 to 1.08 |
| Urgent CS | 6 179 | 10.0 | 2 934 | 25.1 | 2.51 | 2.40 to 2.62 |
| Emergency CS | 300 | 0.9 | 155 | 1.3 | 1.40 | 1.16 to 1.70 |
| Vaginal delivery (both) | 37 239 | 91.0 | 8 971 | 83.7 | 0.92 | 0.91 to 0.93 |
| Instrumental delivery | 1 767 | 4.3 | 676 | 6.3 | 1.46 | 1.34 to 1.59 |
| Urgent CS | 1 774 | 4.3 | 967 | 9.0 | 2.08 | 1.93 to 2.25 |
| Emergency CS | 152 | 0.4 | 102 | 1.0 | 2.56 | 2.00 to 3.29 |
The effects of induction and mode of delivery to childbirth experience in previous studies
| Measure | Exposure | Association | |
|---|---|---|---|
| Adler et al. (2020) [ | VAS (<5 vs. ≥5) | Induction (ref. spontaneous) | aOR = 1.6 (1.4-1.9) |
| Falk et al. (2019) [ | VAS (1-3 vs. 4-10) | Induction (ref. spontaneous) | aOR = 1.69 [1.44-1.98] |
| Hildingsson et al. (2011) [ | Negative (vs. positive) birth experience | Induction (ref. spontaneous) | aOR = 1.5 [1.0-2.3] |
| Schaal et al. (2019) [ | CEQ (Overall Score) | Induction | m = 3.00 (SD=0.30), |
| Spontaneous | m = 3.10 (SD=0.29), | ||
| Shetty et al. (2005) | Satisfied with labour (4-5 vs. 1-3) | Induction (ref. spontaneous) | RR = 0.89 (0.80-0.96) |
| Waldenström et al. (2004) [ | Negative (1-2) birth experience (vs. positive, 3-7) | Induction (ref. spontaneous) | RR = 2.4 [1.7-3.4] |
| Adler et al. (2020) [ | VAS (<5 vs. ≥5) | CS (ref. SVD) | aOR = 4.5 (3.7–5.5) |
| IVD (ref. SVD) | aOR = 3.3 (2.7–4.0) | ||
| Blomquist et al. (2011) [ | VAS (0-100); Salmon score: Fulfillment/ Distress/ Difficulty | Planned CS | 90.9; 0.23/-0.24/-0.54 |
| Unplanned CS | 73.9; -0.61/0.62/0.41/ | ||
| SVD | 86.8; 0.14/-0.19/0.03 | ||
| OVD | 76.2; 0.11/0.05/0.20 | ||
| Bossano et al. (2017) [ | Salmon score: Fulfillment/ Distress/ Difficulty | Planned CS | 0.53/-0.16/-0.43 |
| Unplanned CS | 0.02/0.20/0.17 | ||
| SVD | 0.47/-0.52/-0.13 | ||
| OVD | 0.15/0.02/0.47 | ||
| Carquillat et al. (2016) [ | NRS from 0 (=very bad experience) to 10 (=very good experience) | SVD | 7.94 (2.14) |
| IVD | 6.96 (2.43) | ||
| Elective CS | 7.00 (1.97) | ||
| Emergency CS | 5.12 (3.18) | ||
| Falk et al. (2019) [ | VAS(1-3) | IVD (ref. SVD) | aOR = 2.9 (2.3–3.6) |
| Emergency CS (ref. SVD) | aOR = 4.0 (3.3–4.9) | ||
| Hildingsson et al. (2011) [ | Negative vs. positive birth experience | IVD (ref. SVD) | OR = 1.4 (0.7–2.4) |
| Unplanned CS (ref. SVD) | OR = 3.1 (1.9–5.0) | ||
| Kempe & Vikström-Bolin (2020) [ | Average VAS (0-10) | SVD | 8.18 |
| OVD | 6.85 | ||
| Unplanned CS | 7.12 | ||
| Rijnders et al. (2008) | Negative recall | OVD or Unplanned CS (ref. SVD) | aOR = 2.6 (1.6–4.1) |
| Spaich et al. (2013) [ | Good/very good' satisfaction with childbirth | Normal delivery | 89 % |
| Primary CS | 94 % | ||
| Secondary CS | 87 % | ||
| Emergency CS | 89 % | ||
| OVD | 93 % | ||
| Waldenström et al. (2004) [ | Negative vs. positive birth experience (7-point scale 1-2 vs. 3-7) | IVD (ref. SVD) | RR = 4.0 (2.7–5.9) |
| Elective CS (ref. SVD) | RR = 1.1 (0.5–2.4) | ||
| Emergency CS (ref. SVD) | RR = 5.7 (4.1–7.9) | ||
CEQ Childbirth Experience Questionnaire, SVD spontaneous vaginal delivery, normal vaginal, IVD instrumental vaginal delivery, OVD operative vaginal delivery, CScaesarean section, NRS numeric rating scale