Literature DB >> 24352770

The devastating effects of tibial nonunion on health-related quality of life.

Mark R Brinker1, Bryan D Hanus2, Milan Sen3, Daniel P O'Connor4.   

Abstract

BACKGROUND: Tibial nonunion is disabling, but to our knowledge no quantitative evaluation of its effect on health-related quality of life has been reported.
METHODS: We evaluated 243 tibial shaft fracture nonunions in 237 consecutive patients (seventy-nine female [age, 49.4 ± 14.9 years] and 158 male [age, 46.3 ± 15.4 years]) who were referred to a single surgeon at our tertiary care center over a ten-year period. The most frequently affected tibial segment was the distal third (49%), and infection was present in 18% of all cases.
RESULTS: The Short Form (SF)-12 Physical Component Summary score averaged 27.4 ± 6.7, indicating an extremely disabling effect on physical health. The AAOS (American Academy or Orthopaedic Surgeons) Lower Limb Core Scale score averaged 52.0 ± 19.4, also consistent with high levels of physical disability attributable to the lower limb. The SF-12 Mental Component Summary score averaged 42.3 ± 7.1, indicating a substantial detrimental effect on mental health.
CONCLUSIONS: The impact of tibial shaft fracture nonunion on physical health was comparable with the reported impact of end-stage hip arthrosis and worse than that of congestive heart failure. Tibial shaft fracture nonunion is a devastating chronic medical condition that negatively affects both physical and mental health and quality of life.

Entities:  

Mesh:

Year:  2013        PMID: 24352770     DOI: 10.2106/JBJS.L.00803

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  43 in total

1.  Local transplantation of bone marrow concentrated granulocytes precursors can cure without antibiotics infected nonunion of polytraumatic patients in absence of bone defect.

Authors:  Philippe Hernigou; Matthieu Trousselier; François Roubineau; Charlie Bouthors; Nathalie Chevallier; Helene Rouard; Charles Henri Flouzat-Lachaniette
Journal:  Int Orthop       Date:  2016-03-01       Impact factor: 3.075

2.  Treatment outcomes for infected juxta-articular knee nonunions.

Authors:  A Lagaras; V Kontogeorgakos; S Varitimidis; K N Malizos
Journal:  Hippokratia       Date:  2018 Oct-Dec       Impact factor: 0.471

3.  Single-stage treatment of infected tibial non-unions and osteomyelitis with bone marrow granulocytes precursors protecting bone graft.

Authors:  Philippe Hernigou; Arnaud Dubory; Yasuhiro Homma; Charles Henri Flouzat Lachaniette; Nathalie Chevallier; Helene Rouard
Journal:  Int Orthop       Date:  2017-11-13       Impact factor: 3.075

4.  Long-term functional outcome and quality of life after successful surgical treatment of tibial nonunions.

Authors:  Florian Wichlas; Serafim Tsitsilonis; Alexander C Disch; Norbert P Haas; Christian Hartmann; Frank Graef; Philipp Schwabe
Journal:  Int Orthop       Date:  2014-12-20       Impact factor: 3.075

5.  Activation of hedgehog signaling by systemic agonist improves fracture healing in aged mice.

Authors:  Jennifer A McKenzie; Clayton Maschhoff; Xiaochen Liu; Nicole Migotsky; Matthew J Silva; Michael J Gardner
Journal:  J Orthop Res       Date:  2018-12-27       Impact factor: 3.494

6.  Ilizarov fixator combined with an intramedullary nail for tibial nonunions with bone loss: is it effective?

Authors:  Deniz Gulabi; Mehmet Erdem; Gultekin Sıtkı Cecen; Cem Coskun Avci; Necdet Saglam; Fevzi Saglam
Journal:  Clin Orthop Relat Res       Date:  2014-12       Impact factor: 4.176

7.  Predictors of Patient Reported Pain After Lower Extremity Nonunion Surgery: The Nicotine Effect.

Authors:  Anthony V Christiano; Christian A Pean; Sanjit R Konda; Kenneth A Egol
Journal:  Iowa Orthop J       Date:  2016

8.  Radiographic union score for tibia fractures predicts success with operative treatment of tibial nonunion.

Authors:  Anthony V Christiano; Abraham M Goch; Philipp Leucht; Sanjit R Konda; Kenneth A Egol
Journal:  J Clin Orthop Trauma       Date:  2018-10-19

9.  Can low intensity pulsed ultrasound (LIPUS) be used as an alternative to revision surgery for patients with non-unions following fracture fixation?

Authors:  Vidhi Adukia; Zahra Al-Hubeshy; Jitendra Mangwani
Journal:  J Clin Orthop Trauma       Date:  2020-11-21

10.  Long-term patient-related quality of life after fracture-related infections of the long bones.

Authors:  Nike Walter; Markus Rupp; Katja Hierl; Christian Pfeifer; Maximilian Kerschbaum; Thilo Hinterberger; Volker Alt
Journal:  Bone Joint Res       Date:  2021-05       Impact factor: 5.853

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