Literature DB >> 3573155

Splice acceptor site for the env message of Moloney murine leukemia virus.

P A Lazo, V Prasad, P N Tsichlis.   

Abstract

We report the isolation and sequence of a cDNA clone containing part of the env message of the Moloney murine leukemia virus (MoMuLV). This clone was derived from a rat thymic lymphoma induced by MoMuLV. The AG acceptor site employed in this message is located at position 5490 in the MoMuLV genome. This splice site is detectable at the cDNA level by the creation of a novel SacI restriction site not present in the viral genome. In the -1 to -40 region, this AG acceptor site is preceded by four conserved heptanucleotides (PyXPyTPuAPy) that may function as acceptors for removal of the 5' end of the intron.

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Year:  1987        PMID： 3573155      PMCID： PMC254215     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  26 in total

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Authors:  T R Cech
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9.  DNA sequencing with chain-terminating inhibitors.

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Authors:  A R Krainer; T Maniatis
Journal:  Cell       Date:  1985-10       Impact factor: 41.582
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  14 in total

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8.  Adaptive evolution of a tagged chimeric gammaretrovirus: identification of novel cis-acting elements that modulate splicing.

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10.  Development of physical forms of unintegrated retroviral DNA in mouse spinal cord tissue during ts1-induced spongiform encephalomyelopathy: elevated levels of a novel single-stranded form in paralyzed mice.

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