Literature DB >> 35703770

Multilevel Determinants of Rapid Antiretroviral Treatment Implementation and Demand in Miami-Dade County.

Audrey Harkness1, Andrew J Wawrzyniak2, Michael A Kolber3, Kira Villamizar4, Valeria Botero3, Jacqueline E Rodriguez3, Jessica L Orr3, Julia Zukerberg5, Allan E Rodríguez3.   

Abstract

BACKGROUND: Rapidly linking newly diagnosed HIV patients to antiretroviral treatment (ART) is the best practice for achieving optimal treatment outcomes, including viral suppression. However, rapid ART implementation varies throughout the United States, highlighting the importance of identifying rapid ART implementation determinants in US HIV epicenters, such as Miami-Dade County (MDC).
METHODS: Clinic focus groups (N = 4 clinics) and patient interviews (N = 31 recently diagnosed patients) systematically and qualitatively assessed rapid ART implementation determinants in MDC. Independent coders analyzed focus groups and interviews using a directed content analysis approach guided by the Consolidated Framework for Implementation Research.
RESULTS: For clinic stakeholders, key rapid ART implementation determinants included the following: complexity and adaptability (innovation characteristics); networks between clinics and patient needs rooted in structural inequities (outer setting); leadership and available resources (inner setting); staff/provider flexibility (characteristics of individuals); and appointing patient navigators and champions (process). For patients, key determinants included complexity and relative advantage of rapid treatment (innovation characteristics); patient needs and clinic networks (outer setting); provider knowledge and skills (inner setting); provider warmth and affirmation (characteristics of individuals); and need for improved outreach (process).
CONCLUSIONS: Multilevel factors impact clinic implementation and patient demand for rapid ART in MDC. Informed by these factors, we identified potential implementation strategies to enhance rapid ART implementation throughout MDC. These implementation strategies can be tested in an implementation trial, enhancing the toolkit of strategies to ensure that evidence-based tools, particularly rapid ART, are readily available to the most impacted communities.
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2022        PMID: 35703770      PMCID: PMC9204784          DOI: 10.1097/QAI.0000000000002978

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.771


  22 in total

1.  Three approaches to qualitative content analysis.

Authors:  Hsiu-Fang Hsieh; Sarah E Shannon
Journal:  Qual Health Res       Date:  2005-11

Review 2.  Rapid initiation of antiretroviral therapy at HIV diagnosis: definition, process, knowledge gaps.

Authors:  M A Boyd; M Boffito; A Castagna; V Estrada
Journal:  HIV Med       Date:  2019-03       Impact factor: 3.180

3.  HIV Viral Load and Transmissibility of HIV Infection: Undetectable Equals Untransmittable.

Authors:  Robert W Eisinger; Carl W Dieffenbach; Anthony S Fauci
Journal:  JAMA       Date:  2019-02-05       Impact factor: 56.272

4.  Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science.

Authors:  Laura J Damschroder; David C Aron; Rosalind E Keith; Susan R Kirsh; Jeffery A Alexander; Julie C Lowery
Journal:  Implement Sci       Date:  2009-08-07       Impact factor: 7.327

5.  Effects of a multicomponent intervention to streamline initiation of antiretroviral therapy in Africa: a stepped-wedge cluster-randomised trial.

Authors:  Gideon Amanyire; Fred C Semitala; Jennifer Namusobya; Richard Katuramu; Leatitia Kampiire; Jeanna Wallenta; Edwin Charlebois; Carol Camlin; James Kahn; Wei Chang; David Glidden; Moses Kamya; Diane Havlir; Elvin Geng
Journal:  Lancet HIV       Date:  2016-08-27       Impact factor: 12.767

6.  Making sense of implementation theories, models and frameworks.

Authors:  Per Nilsen
Journal:  Implement Sci       Date:  2015-04-21       Impact factor: 7.327

7.  Implementation Mapping: Using Intervention Mapping to Develop Implementation Strategies.

Authors:  Maria E Fernandez; Gill A Ten Hoor; Sanne van Lieshout; Serena A Rodriguez; Rinad S Beidas; Guy Parcel; Robert A C Ruiter; Christine M Markham; Gerjo Kok
Journal:  Front Public Health       Date:  2019-06-18

8.  Implementation of a Rapid Entry Program Decreases Time to Viral Suppression Among Vulnerable Persons Living With HIV in the Southern United States.

Authors:  Jonathan Colasanti; Jeri Sumitani; C Christina Mehta; Yiran Zhang; Minh Ly Nguyen; Carlos Del Rio; Wendy S Armstrong
Journal:  Open Forum Infect Dis       Date:  2018-06-28       Impact factor: 3.835

9.  The Implementation Research Logic Model: a method for planning, executing, reporting, and synthesizing implementation projects.

Authors:  Justin D Smith; Dennis H Li; Miriam R Rafferty
Journal:  Implement Sci       Date:  2020-09-25       Impact factor: 7.327

10.  Immediate Antiretroviral Therapy: The Need for a Health Equity Approach.

Authors:  Ofole Mgbako; Magdalena E Sobieszczyk; Susan Olender; Peter Gordon; Jason Zucker; Susan Tross; Delivette Castor; Robert H Remien
Journal:  Int J Environ Res Public Health       Date:  2020-10-08       Impact factor: 3.390

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