Literature DB >> 3570290

Microinjection of normal cell extracts into Fanconi anemia fibroblasts corrects defective scheduled DNA synthesis recovery after 8-methoxypsoralen plus UVa treatment.

M M Gök, E Wunder.   

Abstract

Fanconi anemia (FA) cells show an increased sensitivity to 8-methoxypsoralen (8-MOP) plus UVa treatment; after an initial reduction of their semiconservative DNA synthesis rate, they do not recover like normal cells. We microinjected extracts from normal cells into FA fibroblasts from complementation group A and determined semiconservative DNA synthesis rates by autoradiography; the hampered recovery phase was completely restored.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3570290     DOI： 10.1007/bf00284106

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  13 in total

1.  Mitomycin-induced chromatid breaks in HeLa cells: a consequence of incomplete DNA replication.

Authors:  M A Sognier; W N Hittelman
Journal:  Cancer Res       Date:  1986-08       Impact factor: 12.701

2.  Two complementation groups of Fanconi's anemia differ in their phenotypic response to a DNA-crosslinking treatment.

Authors:  E Moustacchi; D Papadopoulo; C Diatloff-Zito; M Buchwald
Journal:  Hum Genet       Date:  1987-01       Impact factor: 4.132

3.  A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.

Authors:  M S Sasaki; A Tonomura
Journal:  Cancer Res       Date:  1973-08       Impact factor: 12.701

4.  DNA semi-conservative synthesis in normal and Fanconi anemia fibroblasts following treatment with 8-methoxypsoralen and near ultraviolet light or with X-rays.

Authors:  E Moustacchi; C Diatloff-Zito
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

5.  Response of lymphocytes from Fanconi's anemia patients and their heterozygous relatives to 8-methoxy-psoralene in a cloning survival test system.

Authors:  E Wunder; B Fleischer-Reischmann
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

6.  Suppression of spontaneous and mitomycin C-induced chromosome aberrations in Fanconi's anemia by cell fusion with normal human fibroblasts.

Authors:  M C Yoshida
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

7.  Differential sensitivity of Fanconi anaemia lymphocytes to the clastogenic action of cis-diamminedichloroplatinum (II) and trans-diamminedichloroplatinum (II).

Authors:  E H Poll; F Arwert; H Joenje; A H Wanamarta
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 8.  Genetically determined chromosome instability syndromes.

Authors:  T M Schroeder
Journal:  Cytogenet Cell Genet       Date:  1982

9.  Genetic heterogeneity of Fanconi's anemia demonstrated by somatic cell hybrids.

Authors:  S Zakrzewski; K Sperling
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

10.  Identification of two complementation groups in Fanconi anemia.

Authors:  G Duckworth-Rysiecki; K Cornish; C A Clarke; M Buchwald
Journal:  Somat Cell Mol Genet       Date:  1985-01
View more
  2 in total

1.  Fanconi's anaemia: correlation of genetic complementation group with psoralen/UVA response.

Authors:  M Digweed; S Zakrzewski-Lüdcke; K Sperling
Journal:  Hum Genet       Date:  1988-01       Impact factor: 4.132

2.  Irreversible repression of DNA synthesis in Fanconi anemia cells is alleviated by the product of a novel cyclin-related gene.

Authors:  M Digweed; U Günthert; R Schneider; H Seyschab; R Friedl; K Sperling
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.