Literature DB >> 3569491

Reduction of body fat stores by inhibition of prolactin secretion.

A H Cincotta, A H Meier.   

Abstract

Reductions of prolactin secretion by bromocriptine treatment for 24 days reduced fat stores (abdominal and epididymal fat depots) in hamsters by 25-49% compared with control animals. However, body weights and food consumption were not affected. These results further substantiate an important role for prolactin in regulation of fat metabolism and indicate that bromocriptine might be used to decrease fat stores.

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Year:  1987        PMID: 3569491     DOI: 10.1007/bf01940433

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

1.  Prolactin, growth hormone, luteinizing hormone receptors, and seasonal changes in testicular activity in the golden hamster.

Authors:  F Bex; A Bartke; B D Goldman; S Dalterio
Journal:  Endocrinology       Date:  1978-12       Impact factor: 4.736

2.  Circadian component in the fattening and reproductive responses to prolactin in the hamster.

Authors:  M M Joseph; A H Meier
Journal:  Proc Soc Exp Biol Med       Date:  1974-09

3.  Diurnal variations of the fattening response to prolactin in the golden top minnow, Fundulus chrysotus.

Authors:  R W Lee; A H Meier
Journal:  J Exp Zool       Date:  1967-12

4.  A broad spectrum of prolactin suppression by bromocriptine in hyperprolactinemic women: a study of serum prolactin and bromocriptine levels after acute and chronic admknistration of bromocriptine.

Authors:  M O Thorner; H F Schran; W S Evans; A D Rogol; J L Morris; R M MacLeod
Journal:  J Clin Endocrinol Metab       Date:  1980-06       Impact factor: 5.958

5.  Prolactin permits the expression of a circadian variation in lipogenic responsiveness to insulin in hepatocytes of the golden hamster (Mesocricetus auratus).

Authors:  A H Cincotta; A H Meier
Journal:  J Endocrinol       Date:  1985-08       Impact factor: 4.286

6.  Seasonal obesity in Syrian hamsters: effects of age, diet, photoperiod, and melatonin.

Authors:  G N Wade; T J Bartness
Journal:  Am J Physiol       Date:  1984-08

7.  Photoperiodic control of body weight and energy metabolism in Syrian hamsters (Mesocricetus auratus): role of pineal gland, melatonin, gonads, and diet.

Authors:  T J Bartness; G N Wade
Journal:  Endocrinology       Date:  1984-02       Impact factor: 4.736

8.  Prolactin permits the expression of a circadian variation in insulin receptor profile in hepatocytes of the golden hamster (Mesocricetus auratus).

Authors:  A H Cincotta; A H Meier
Journal:  J Endocrinol       Date:  1985-08       Impact factor: 4.286

  8 in total
  2 in total

Review 1.  Drug-induced changes in prolactin secretion. Clinical implications.

Authors:  K Hell; H Wernze
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Nov-Dec

2.  Timed bromocriptine administration reduces body fat stores in obese subjects and hyperglycemia in type II diabetics.

Authors:  A H Meier; A H Cincotta; W C Lovell
Journal:  Experientia       Date:  1992-03-15
  2 in total

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