Literature DB >> 35688586

Effect of eHealth-delivered exercise programmes on balance in people aged 65 years and over living in the community: a systematic review and meta-analysis of randomised controlled trials.

Meghan Ambrens1,2, Stephanie Alley3, Juliana S Oliveira4,5, Quyen To3, Kim Delbaere2,6, Corneel Vandelanotte3, Anne Tiedemann4,5.   

Abstract

INTRODUCTION: Exercise that challenges balance is proven to prevent falls in community-dwelling older people, yet widespread implementation and uptake of effective programmes is low. This systematic review and meta-analysis synthesised the evidence and evaluated the effect of eHealth-delivered exercise programmes compared with control on balance in community-dwelling people aged ≥65 years.
METHODS: Nine databases including MEDLINE, CINAHL and Embase, were searched from inception to January 2022 to identify randomised controlled trials evaluating eHealth-delivered exercise programmes for community-dwelling people aged ≥65 years, published in English that included a balance outcome. Primary outcomes were static and dynamic balance. Secondary outcomes included fall risk and fear of falling. We calculated standardised mean differences (SMDs, Hedges' g) with 95% CIs from random effects meta-analyses.
RESULTS: We identified 14 eligible studies that included 1180 participants. Methodological quality ranged from 3 to 8 (mean, 5). The pooled effect indicated that eHealth-delivered exercise programmes have a medium significant effect on static balance (11 studies; SMD=0.62, 95% CI 0.27 to 0.72) with very low-quality evidence. There was small statistically significant effect on dynamic balance (14 studies; SMD=0.42, 95% CI 0.11 to 0.73) with very low-quality evidence, and fall risk (5 studies; SMD=0.32, 95% CI 0.00 to 0.64) with moderate-quality evidence. No significant effect of eHealth programmes on fear of falling was found (four studies; SMD=0.10, 95% CI -0.05 to 0.24; high-quality evidence).
CONCLUSION: This review provides preliminary evidence that eHealth-delivered exercise programmes improved balance and reduced fall risk in people aged ≥65 years. There is still uncertainty regarding the effect of eHealth delivered exercise programmes on fear of falling. PROSPERO REGISTRATION NUMBER: CRD42018115098. © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  geriatric medicine; preventive medicine; public health; rehabilitation medicine; telemedicine

Mesh:

Year:  2022        PMID: 35688586      PMCID: PMC9189851          DOI: 10.1136/bmjopen-2021-051377

Source DB:  PubMed          Journal:  BMJ Open        ISSN: 2044-6055            Impact factor:   3.006


We conducted this systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and followed a prespecified protocol registered on PROSPERO. We had specific criteria that allowed for the inclusion of studies with both generally healthy participants and those with selected clinical conditions. We also ensured the inclusion of as many relevant studies as possible by searching across nine databases, conducting a thorough hand search of relevant published literature and consulting with experts in the field. Included studies had to comprise a measure of balance and we may have missed relevant studies that included measures of falls. We only included outcome data from the immediate postintervention time point, which limits the interpretation of results to the short-term.

Introduction

Ageing is associated with a decline in the physiological systems responsible for postural stability and hence an increase in the risk of falls.1 A fall is defined as ‘an unexpected event in which the participants come to rest on the ground, floor, or other lower level’.2 Each year approximately one-third of community-dwelling people aged 65 years and over experience a fall.3 4 Forty per cent of injuries requiring hospital admission are due to falls, and in 2016–2017 more than 125 000 Australians aged 65 years or over were hospitalised due to a fall.5 6 Falls place a significant burden on health systems and can result in serious long-term costs to the individual.7 Falls can also result in the loss of independence, depression, social isolation and admission of the older person to a care facility.7 As such, fall prevention is a public health priority. There is clear evidence that exercise is crucial for preventing falls in community-dwelling older people.8 However, the effect on falls varies by exercise type. A Cochrane systematic review that included 108 studies of exercise, established that exercise that challenges balance has the greatest effect on both the rate of falls (24% reduction) and risk of falls (13% reduction) in community-dwelling older people.8 Despite the benefits of exercise for preventing falls, widespread implementation and adherence to effective programmes is poor, significantly reducing the population-wide impact.9 Furthermore, the 2020 WHO guidelines on physical activity and sedentary behaviour recommend that older adults should undertake multicomponent physical activity that emphasises functional balance and strength training at least three-times per week to enhance functional capacity and prevent falls.10 Therefore, exploring the effectiveness of novel exercise programmes with potential for wide reach that can improve balance is important. Advances in technology have led to new ways to deliver exercise-based programmes. Such technology-based programmes, commonly referred to as electronic-Health (eHealth), that use the internet, websites, mobile applications (apps) or exergames, may provide effective alternatives to more traditional modes of delivering exercise-based programmes to improve balance and prevent falls, and increase access to such programmes. Previous studies show that eHealth interventions can successfully improve the health and physical activity of older people,11–16 and adherence by some older people is higher for technology-delivered interventions compared with traditional interventions, independent of study site, level of supervision and mode of delivery.17 eHealth-delivered exercise programmes are a safe way to exercise, and many older people perceive them as fun and enjoyable.18–22 This mode of delivery has also been successful for improving balance in younger adults, aged 18+ years, with a number of systematic reviews evaluating the effectiveness of specific, technology-based approaches to improving balance or reducing fall risk in adults.23–26 Given the lack of systematic reviews and meta-analyses on the effectiveness of eHealth-delivered exercise programmes for improving balance in older people, further evaluation of the role of technology-driven platforms is needed. This systematic review and meta-analysis aimed to synthesise the evidence and evaluated the effect of eHealth-delivered exercise programmes on balance in people aged 65 years and older living in the community compared with a control.

Methods

Protocol

This review was registered on the PROSPERO database and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.27 The systematic review protocol has been published and provides a full outline of the methods.28 A summary of the methods is reported in this paper.

Data sources

A database search was conducted from inception to January 2022 of MEDLINE, CINAHL Complete, Embase, PsychINFO, Scopus, Web of Science, PubMed Central, Cochrane Database Central and PEDro. The protocol28 details the complete search strategy used. Online supplemental figure 1 provides the MEDLINE search strategy.

Eligibility criteria

Studies included in this systematic review met the following criteria: (1) published in English, (2) randomised controlled trials (RCTs), (3) participants were community-dwelling people aged ≥65 years, (4) reported data for a validated measure of balance, (5) included eHealth delivery of an exercise programme compared with no intervention, usual care or wait-list control. Studies that did not meet these criteria were excluded. We included all RCT designs such as crossover, cluster, patient-randomised clinical trials that examined the effect of eHealth-delivered exercise programmes vs a control group. Single and multi-factorial interventions were also included. Studies published only as abstracts or yet to be published were excluded due to possible data inaccuracy and incompleteness.

Outcome measures

The primary outcome measure was balance, defined as staying upright and steady when stationary, such as when standing, or sitting, or during movement.29 Technically, balance is defined as ‘the ability to maintain the projection of the body’s centre of mass (CoM) within manageable limits of the base of support, as in sitting or standing, or in transit to a new base of support, as in walking’.30 The balance outcomes were further categorised as static or dynamic measures of balance in the analyses. Static balance refers to maintaining balance when the body has a constant or static base of support.29 Whereas dynamic balance refers to maintaining balance during movement from one base of support to another, such as when walking.29 In the absence of functional measures of balance, we included studies which reported direct measures of balance, such as those measured with a force platform. Fall risk, fear of falling and fall rate were included as secondary outcomes. We included studies that used either validated self-report questionnaires or performance-based measures for these outcomes.

Study selection

After pilot-testing criteria for full-text articles, screening for eligible studies was conducted independently by two reviewers (MA, KLA/RS). An electronic screening form was used, and screening occurred in stages: first, titles were screened, followed by abstracts and finally full-text articles were screened. Conflicts were resolved by consensus from AT, KD and CV.

Data extraction

Data extraction was completed by two researchers independently from one another (MA, QT), and conflicts were resolved by a third reviewer (SA). Data were extracted using a piloted electronic data extraction form, and according to the PRISMA statement.27 Where data were missing, study authors were contacted by email to provide further information. Where the authors did not reply within 2 weeks, a second email was sent as a reminder. The following data were extracted from each study: author, year of publication, country, sample characteristics (sample size, age, sex of participants and health status), study design: including number of study arms, recruitment sources, eligibility criteria, setting, delivery method and technology used, intervention description, comparator, intervention duration and frequency, assessment time-points. Also extracted were data on drop out, attrition, adverse events and intervention features such as implementation fidelity, evidenced-based theory, tailoring, supervision, intervention acceptability. Primary and secondary outcome data were extracted for preintervention and postintervention timepoints. Where data were available for more than one postintervention timepoint, we included the data from the timepoint closest to intervention completion.

Methodological quality and risk of bias assessment

The PEDro scale (1–10) was used to assess the methodological quality of the included studies. PEDro scores were extracted from the PEDro database.31 The PEDro scale assesses the internal validity of an RCT by evaluating 11 items: participant eligibility criteria, random allocation, concealed allocation, homogeneity of groups at baseline, blinding of subjects, blinding of therapist, blinding of assessor, completeness of follow-up, intention-to-treat analysis, between-group statistical analysis, and variability and point measures.32 A score of 10 is considered to be methodologically excellent, whereas 0 demonstrates poor methodological quality.32 Methodological quality was not an inclusion criterion for this review. In addition to the PEDro scale, we also used the Cochrane Risk of Bias to assess the risk of bias in each included study. The Cochrane Risk of Bias was undertaken by two independent reviewers (MA, SA) with conflicts resolved by a third reviewer (CV). Risk of bias is assessed across a number of domains as a judgement of low risk, high risk, or unclear.33

Assessment of quality of evidence

To evaluate overall quality of evidence we used the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system. The GRADE appraisal was conducted by pairs of independent reviewers (MA, JSO) and guided by the Cochrane Handbook for Systematic Reviews.33 This is a subjective evaluation of the quality of the evidence as high, moderate, low or very low based on the presence or extent of the following factors: risk of bias, imprecision and inconsistency of the effect. The GRADE classification was downgraded from high quality by one level for each factor encountered: (1) design limitations (>25% of studies with low methodological quality based on the Cochrane Risk of bias), (2) inconsistency of results (large heterogeneity between the studies I2>50%), (3) imprecision (<400 participants for each outcome).33 We did not consider indirectness as it encompasses a specific population (older people) with relevant outcome measures (balance) and direct comparisons. We were unable to consider publication bias for secondary outcome measures due to the limited number of studies that collected measures for the fall-related outcome measures.33

Statistical analysis

We performed meta-analyses with Comprehensive Meta-Analysis software (V.3, Biostat, Englewood, New Jersey, USA) using the random effects models for primary and secondary outcome measures. The random effects model was chosen given the heterogeneity of the population and the interventions being evaluated. We calculated treatment effects for the continuous variables using standardised mean differences (SMDs, Hedges’ g) standardised by postscore standard deviation (or its estimate) with 95% CIs, for either between-group differences in point estimates at the follow-up time points or between-group differences in change scores based on available data. SMDs were calculated using the premean and postmean and SD. Where this was not available, we used the mean change score. Effect sizes were categorised as small (0.2), medium (0.5) or large (0.8 or greater).34 We visually inspected the forest plot for evidence of heterogeneity among studies with consideration of the I2 and χ2 tests. We determined clinical heterogeneity by consensus among the investigators on the basis of collective experience in the field.

Results

Flow of studies included in this review

The initial search of the databases resulted in 1080 publications. An additional hand search, including the reference lists of relevant review articles found a further 40 publications. After removing duplicate papers, 783 publications were screened by title and abstract. Forty-five publications reported on potentially eligible studies before full-text screening. After the full-text screen, 14 studies, reported by 15 manuscripts, were identified as eligible and included in this study. Schoene et al35 conducted a study involving interactive cognitive-motor step training, however this paper did not report the balance outcomes measured during this study. These balance outcomes were reported in Gschwind et al36 as the step-mat-training (SMT) intervention group. This review extracted outcome data for the SMT group only from Gschwind et al36 paper, all other data pertaining to this study (including for the control group) were extracted from Schoene et al.35 Figure 1 outlines the PRISMA study flow of studies included in this review.
Figure 1

Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow of studies through the review.RCT, randomised controlled trial.

Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow of studies through the review.RCT, randomised controlled trial. We pooled all included studies in the primary meta-analysis evaluating the effect of interventions that use an eHealth technology to deliver an exercise programme to older people.

Risk of bias and quality

Table 1 reports the methodological quality of eligible studies. The total PEDro scores ranged from 3 to 8 (mean of 5). For the static balance outcome five studies out of 11 (45%) were of high methodological quality (a score ≥6).18 36–39 For the dynamic balance outcome, 5 studies out of 14 (36%) were of high methodological quality.18 36–39 All participants were randomly allocated and provided the calculation of point estimates and variability (PEDro items 2 and 11). Four studies out of 14 (29%) did not undertake an intention-to-treat analysis18 40–42 and 3 studies provided insufficient information to determine this.43–45 None of the studies included blinded participants or blinded therapists, however, blinding of participants or therapists is not possible for exercise interventions. Table 2 reports the quality of the evidence. Figure 2 presents the risk of bias.
Table 1

Summary of the characteristics of the included studies

Study author; countryStudy design; sample size; PEDro scoreSampleeHealth exercise interventionComparatorAdverse eventsIntervention acceptability and how it was assessed
Mean age; % female; health statusIntervention contentOutcome measures: primary and secondaryTailored progression of exercisesDosage: duration; session length; frequencySetting
Bieryla and Dold; USA42RCT; N=12; 381.5±5.5; 83%; healthyExercises: yoga (half-moon, chair, warrior), aerobic (torso twist), balance games (soccer heading, ski jump)Primary: FAB, BBS3 wk; 30 min; 3× wkCentre; supervisedNot assessed
Chow and Mann; Hong Kong46RCT; N=20; 370.4; 65%; healthyExercises: Tiger Woods PGA Tour 13 golf gamePrimary: SLS, TUG2 wk; 30–45 min; dailyCentre; supervisedTable gamesNot assessed
Delbaere et al; Australia39RCT;N=503; 877.1±5.5; 67%; healthyExercises: balance and lower limb muscle strength; health educationPrimary: standing balance, TUGSecondary: PPA, icon-FES↑ intensity; ↑ challenge↑ duration52 wk (balance measures),104 wk (fall measures); 120 min per wkHome; unsupervisedHealth education programme delivered via iPad5 fallsSUS to assess usability
Gschwind et al; Australia, Germany, Spain36RCT; N=153; 674.7±6.3; 61%; healthyExercise: balance and muscle strength; educational booklet on general health and fall preventionPrimary: tandem stance, TUG Secondary: icon-FES, PPA16 wk;balance: 40 min; 3× wk.Strength: 15–20 min; 3× wkHome; unsupervisedEducational booklet: general health and fall prevention24 falls (IG: 8, CG: 15)SUS to assess usability and enjoyment; DART to assess user acceptance.
Gschwind et al/ Schoene et al; Australia35 38RCT; n=90; 782±7; 66%; healthyExercises: trail-stepping—visual attention, set-shifting; stepping to connect numbers and letters, Tetris-stepping—visuo-spatial skills, problem-solving; steppingPrimary: standing balance, TUG Secondary: PPA↑ intensity; ↑ challenge16 wk; 20 min; 3× wkHome; unsupervisedEducational booklet: general health and fall preventionNot assessed
Hong et al; South Korea41RCT; N=30; 578.10; 100%; fall riskExercises: resistance, two-legged standing, tandem standing, one-legged standing, semi-tandem standing, tandem walking, turning in a circle, toe stands+nutrition and exercise educationPrimary: BBS Secondary: FES-K↑ intensity12 wk; 20–40 min; 3× wkHome; supervisedNutrition and exercise educationNot assessed
Jung et al; Republic of Korea45RCT; N=24; 474.3±2.1; 100%; fall riskExercises (NWS group): including the wakeboard, Frisbee dog, jet ski and canoe gamesPrimary: functional reach, TUG, BBS8 wk; 30 min; 2× wkCentre: supervisedNot assessed
Lai et al; Taiwan47Cross-over; N=30; 470.6±3.5; 57%; healthyExercises: IVGB stepping exercisePrimary: SLS, BBS6 wk; 30 min; 3× wkCentre; supervisedCross-over trialNot assessed
Lee et al; South Korea37RCT; N=44; 676.15±4.55; 77%; healthyExercises: jogging for gait, swordplay for agility and balance, ski jump for balance, hula-hoop for balance and lower extremity strength, tennis for balance and agility, and step dance for gait for lower extremity strengthPrimary: SLS, BBS6 wk; 60 min; 2× wkCentre: supervised3× fall education sessionsNot assessed
Phirom et al; Thailand43RCT; N=4070.21±4.18; healthyExercises: interactive game-based training which involved stepping on different targets and in different directions and balance trainingPrimary: TUGSecondary: PPA12 wk; 60 min; 3× wkCentre; supervisedNot assessed
Sadeghi et al; Malaysia48RCT; N=64; 571.8±6.09; 0%; healthyExercises (BT group): single-leg stance with eyes open and closed, standing on heels or toes, tandem and semi-tandem foot stance, tandem walking, walking backward and forward, and weight shiftingPrimary: SLS, TUG↑ intensity; ↑ challenge8 wk; 40 min; 3× wkCentre; supervisedEducational material covering cognitive enhancement and fall prevention strategiesNot assessed
Sato et al; Japan44RCT; N=54; 469.25±5.41; 80%; healthyComplete four games—apple game, balloon popping game, tightrope game, one-leg standing gamePrimary: BBS9 wk (24 sessions); 40–60 min; 2–3× wkCentre; supervisedNot assessed
Schoene et al; Australia18RCT; N=37; 777.5±4.5; healthyExercises: a series of stepping challenges+cognitive loadPrimary: SB, AST Secondary: icon-FES, PPA↑ intensity8 wk; 15–20 min; 2–3× wkHome; unsupervisedParticipants were asked whether they enjoyed playing the exergame (YES/NO response)
Whyatt et al; UK40RCT; N=82; 577.18±6.59; 70%; healthyExercises: games targeting components of balance (Apple Catch, Bubble Pop, Avoid the Shark, Smart Shrimp)Primary: SLS, TUG Secondary: ABC Scale↑ challenge5 wk; 30 min; 2× wkCentre: supervisedActivity diariesNot assessed

Wk: week(s); PEDro: Physiotherapy Evidence Database (used to rate the methodological quality of studies—‘poor’ PEDro score of 1–3, ‘moderate’ PEDro score of 4–5 and ‘high’ PEDro score of 6–10); IVGB: interactive video game based; +, plus; ↑, increase; Centre: exercise delivered within a gymnasium, clinic or other facility that is not the participants place of residence; Primary: primary outcome measure, Secondary: secondary outcome measure; Static balance: SLS, Single Leg Stand; SB, Standing Balance; FAB, Fullerton Advanced Balance Scale; Dynamic balance: BBS, Berg Balance Scale; TUG, Timed Up and Go; FR, functional reach; AST, Alternative Step Test; Fear of Falling: Icon-FES, Iconographical Falls Efficacy Scale; FES-K, Falls Efficacy Scale Korea; FES-I, Falls Efficacy Scale-International; Fall risk: PPA, Physiological Profile Assessment; IG, intervention group; CG: control group; NWS group: Nintendo Wii Sports group; NSW BT group: balance training group; SUS: System Usability Scale; DART: Dynamic Acceptable Model for the Re-evaluation of Technologies.

Table 2

Summary of the quality of evidence and strength of recommendation

Quality assessment
Meta-analysisStudy limitations*Inconsistency†Imprecision‡Publication biasOverall GRADE
Static balanceVery low
Dynamic balanceVery low
Fall riskModerate
Fear of fallingHigh

*Risk of bias: we downgraded the evidence if >25% of included studies had a high risk of bias.

†Heterogeneity >50%.

‡We downgraded if there were <400 participants.

↓, downgraded; GRADE, Grading of Recommendations, Assessment, Development and Evaluations.

Figure 2

Risk of bias.

Risk of bias. Summary of the characteristics of the included studies Wk: week(s); PEDro: Physiotherapy Evidence Database (used to rate the methodological quality of studies—‘poor’ PEDro score of 1–3, ‘moderate’ PEDro score of 4–5 and ‘high’ PEDro score of 6–10); IVGB: interactive video game based; +, plus; ↑, increase; Centre: exercise delivered within a gymnasium, clinic or other facility that is not the participants place of residence; Primary: primary outcome measure, Secondary: secondary outcome measure; Static balance: SLS, Single Leg Stand; SB, Standing Balance; FAB, Fullerton Advanced Balance Scale; Dynamic balance: BBS, Berg Balance Scale; TUG, Timed Up and Go; FR, functional reach; AST, Alternative Step Test; Fear of Falling: Icon-FES, Iconographical Falls Efficacy Scale; FES-K, Falls Efficacy Scale Korea; FES-I, Falls Efficacy Scale-International; Fall risk: PPA, Physiological Profile Assessment; IG, intervention group; CG: control group; NWS group: Nintendo Wii Sports group; NSW BT group: balance training group; SUS: System Usability Scale; DART: Dynamic Acceptable Model for the Re-evaluation of Technologies. Summary of the quality of evidence and strength of recommendation *Risk of bias: we downgraded the evidence if >25% of included studies had a high risk of bias. †Heterogeneity >50%. ‡We downgraded if there were <400 participants. ↓, downgraded; GRADE, Grading of Recommendations, Assessment, Development and Evaluations.

Cohort characteristics

Studies included samples ranging from 9 to 503 participants (n=1180). The mean age of participants ranged from 65 to 89 years. Both males and females were included in 11 studies, all had a higher percentage of female participants.18 36–38 40 42 46 47 Two studies included only female participants,41 45 one study included only male participants.48 Every study recruited participants from the general community.18 36–48 Two studies recruited participants with a history of falls.41 45 Table 1 presents a summary of cohort characteristics.

Characteristics of included studies

Publication dates ranged from 2013 to 2021, with 11 (76%) published during or after 2015. Studies were conducted in eight different countries: single studies were conducted in Hong Kong,46 Taiwan,47 the USA,42 the UK,40 Japan,44 Malaysia48 and Thailand43; three studies were conducted in Australia18 36 39 and South Korea37 41 45; and one study was conducted across three countries: Germany, Spain and Australia.38 Details of study characteristics are summarised in table 1.

eHealth-delivered exercise programmes

The duration of the included interventions ranged from 2 to 52 weeks, with a mean duration of 12 weeks. Eleven studies (79%) used a commercially available exergame system to deliver the exercises: five (36%) used the Microsoft Xbox Kinect,38 43 44 46 48 four (29%) studies used the Nintendo Wii console,37 40 42 45 two (14%) used the Dance Dance Revolution StepMania.18 36 Three studies (21%) used customised technologies: an app-based intervention called StandingTall,39 a web-based intervention called telepresence,41 and the Xavix Measured Step System.47 Five studies (36%) used technology to provide a home-based intervention.18 36 38 39 41 Nine studies (64%) used technology to deliver a supervised intervention: participants attended a supervised group class,37 44 46 or a supervised one-on-one session.40 42 43 45 47 48 In seven studies (50%), the control group received no information and were encouraged to continue with normal daily activities.40 42 47 Control participants in five studies (36%) received educational advice related to fall prevention, general health, nutrition and physical activity, in the form of a booklet or classes.36–39 41 Participants in one study continued with the regular, seated social games available at the senior’s activities centre.46

Effect of eHealth-delivered exercise programmes on balance

Eleven studies (79%) measured static balance using static balance,39 single leg stance,37 46–48 tandem stance,38 postural sway,18 36 40 functional reach45 and the Fullerton Advanced Balance Scale.42 The pooled effect of eHealth-delivered exercise programmes on static balance indicates a medium, statistically significant effect compared with control (SMD=0.62, 95% CI 0.27 to 0.72; I2=82%, p=0.001) (figure 3). The pooled results provide very low-quality evidence (GRADE).
Figure 3

Forest plot: Effect size (95% CI) of e-Health interventions on static balance outcome by pooling data from 11 studies comparing e-Health versus control using random-effects meta-analysis (n = 1,056)

Forest plot: Effect size (95% CI) of e-Health interventions on static balance outcome by pooling data from 11 studies comparing e-Health versus control using random-effects meta-analysis (n = 1,056) All 14 studies measured dynamic balance with methods ranging from the Timed Up and Go,36–39 42 43 45–48 the Berg Balance Scale40 41 44 and the Alternative Step test.18 The pooled effect of eHealth-delivered exercise programmes on dynamic balance indicates there was a small, statistically significant effect compared with control (SMD=0.42, 95% CI 0.11 to 0.73; I2=79%, p=0.009) (figure 4). The pooled results provide very low-quality evidence (GRADE). Online supplemental figure 2 provides the Funnel plot for static and dynamic balance.
Figure 4

Forest plot: Effect size (95% CI) of e-Health interventions on dynamic balance outcome by pooling data from 14 Effect size (95% CI) of e-Health interventions on dynamic balance outcome by pooling data from 14 studies comparing e-Health versus control using random-effects meta-analysis (n = 1,180)

Forest plot: Effect size (95% CI) of e-Health interventions on dynamic balance outcome by pooling data from 14 Effect size (95% CI) of e-Health interventions on dynamic balance outcome by pooling data from 14 studies comparing e-Health versus control using random-effects meta-analysis (n = 1,180)

Effect of eHealth-delivered exercise programmes on secondary outcomes

Five studies (36%) measured fall risk using the Physiological Profile Assessment.18 36 38 39 43 The pooled effect of eHealth-delivered exercise programmes on fall risk indicates a small effect compared with control (SMD=0.32, 95% CI 0.00 to 0.64; I2=69.6%, p=0.048). The pooled results provide moderate-quality evidence (GRADE). Four studies (29%) reported measures of fear of falling using the shortened Iconographical Falls Efficacy Scale,18 38 39 or the Fear of Falling Questionnaire.41 The pooled effect indicates no significant effect of eHealth-delivered exercise programmes on fear of falling compared with control (SMD=0.10, 95 % CI −0.05 to 0.24; I2=0.0%, p=0.201). The pooled results provide high-quality evidence (GRADE). Two studies collected data for fall rate.37 39 However, Lee et al37 only reported a baseline measure for fall rate without providing further follow-up data. We were therefore unable to report on fall rate.

Adverse events

Eight included studies (57%) measured adverse events.35–41 46 Of those reported, no major adverse events were related to the intervention.

Discussion

This systematic review and meta-analysis provides preliminary evidence that eHealth-delivered exercise programmes improve balance (static and dynamic) and provide an alternative method of delivering an exercise programme to people aged 65 years or over living in the community. This reviews also demonstrates that an eHealth-delivered exercise programme may improve fall risk in people aged 65 years or over living in the community. However, we are uncertain whether an eHealth-delivered exercise programme improves fear of falling or fall rate in people aged 65 years or over living in the community. There are a number of factors that may have influenced these results. First, the dose and intensity of the prescribed exercise in many of the studies may have been insufficient to substantially improve dynamic balance. A Cochrane review examining the effects of exercise interventions on balance found effective programmes were those attended three times per week for 3 months and involved dynamic exercises in a standing position.29 While in 79% of studies (11/14) participants completed intervention exercises three times per week, only five studies had an exercise duration of 12 or more weeks. Furthermore, a systematic review on falls prevention found greater effects from interventions that challenged balance and included >3 hours per week.49 Six studies (43%) included tailoring (increases in intensity and challenge). In addition, only four studies engaged participants in at least 180 min of exercise per week for the duration of the intervention. Most studies (71%) only engaged participants for between 30 and 120 min of exercise per week. This suggests that the challenge to balance may not have been of a sufficiently high dose. Therefore, our results, which indicate a small but statistically significant effect on dynamic balance, are promising. Further research is needed to explore the effect higher dosage (i.e., tailoring exercises to achieve increased intensity and challenge over the duration of the intervention) has on dynamic balance. Finally, the tools used to measure dynamic balance may not be the most appropriate for the healthy older people. The most frequently used measure of dynamic balance was the Timed-up-and-go (TUG) (10/14). While the TUG is a validated tool and is recommended by the National Institute of Clinical Evidence for the assessment of gait and balance in the prevention of falls in older people,3 research has found the TUG may be more appropriate for frail older people who use walking aids rather than healthy older people.50 The results for the secondary measures related to falls are mixed. While there was a small but significant effect on fall risk compared with the control, there is still uncertainty around the effect eHealth-delivered exercise programmes have on fear of falling. This is despite strong evidence that exercise interventions reduce falls in older community-dwellers.8 There are two possible explanations for these findings. First, to be eligible the included studies had to report on balance, resulting in only a small number (n=5 fall risk; n=4 fear of falling) of studies also reporting a fall-related measure. This suggests we may have missed studies that measured the other fall-related outcomes of interest. Second, it is likely that the studies that reported a fall-related outcome, were not powered to detect an impact on falls (sample sizes ranged from 30 to 503 participants).2

Implications for clinicians and policymakers

Given the often low levels of adherence to exercise-based fall prevention programmes among older people, new delivery methods that improve access and encourage uptake of programmes designed to improve balance and reduce falls are needed. This review demonstrates that eHealth platforms are an effective mode of delivering exercises to improve balance. Although we identified an intervention effect on balance (static and dynamic), not only does this need to be considered in the context of the quality of the evidence but also in the ability to scale up and implement such interventions to large populations where resources are available. Clinicians should consider the use of eHealth platforms for delivering exercise programmes to older people living in the community.

Unanswered questions

Our results identified evidence of the benefit of eHealth-delivered exercise programmes on balance (static and dynamic) in older people living in the community. However, what remains unclear is the effect of eHealth-delivered exercise programmes on fall risk, fear of falling and fall rate in this population. Future research should focus on high-quality studies that deliver the recommended intensity and duration of exercise to provide a sufficiently high challenge to balance and impact on fall-related outcomes in a safe manner. Furthermore, future research needs to explore the long-term impact, cost-effectiveness and sustainability of eHealth-delivered programmes on balance and fall-related outcomes in older people living in the community.
  40 in total

1.  Can a website-delivered computer-tailored physical activity intervention be acceptable, usable, and effective for older people?

Authors:  Rahel Ammann; Corneel Vandelanotte; Hein de Vries; W Kerry Mummery
Journal:  Health Educ Behav       Date:  2012-10-16

2.  Risk factors for falls among elderly persons living in the community.

Authors:  M E Tinetti; M Speechley; S F Ginter
Journal:  N Engl J Med       Date:  1988-12-29       Impact factor: 91.245

3.  Psychometric comparisons of the timed up and go, one-leg stand, functional reach, and Tinetti balance measures in community-dwelling older people.

Authors:  Mau-Roung Lin; Hei-Fen Hwang; Ming-Hsia Hu; Hong-Dar Isaac Wu; Yi-Wei Wang; Fu-Chao Huang
Journal:  J Am Geriatr Soc       Date:  2004-08       Impact factor: 5.562

4.  A Wii Bit of Fun: A Novel Platform to Deliver Effective Balance Training to Older Adults.

Authors:  Caroline Whyatt; Niamh A Merriman; William R Young; Fiona N Newell; Cathy Craig
Journal:  Games Health J       Date:  2015-10-15

Review 5.  Exercise to prevent falls in older adults: an updated systematic review and meta-analysis.

Authors:  Catherine Sherrington; Zoe A Michaleff; Nicola Fairhall; Serene S Paul; Anne Tiedemann; Julie Whitney; Robert G Cumming; Robert D Herbert; Jacqueline C T Close; Stephen R Lord
Journal:  Br J Sports Med       Date:  2016-10-04       Impact factor: 13.800

6.  ICT-based system to predict and prevent falls (iStoppFalls): results from an international multicenter randomized controlled trial.

Authors:  Yves J Gschwind; Sabine Eichberg; Andreas Ejupi; Helios de Rosario; Michael Kroll; Hannah R Marston; Mario Drobics; Janneke Annegarn; Rainer Wieching; Stephen R Lord; Konstantin Aal; Daryoush Vaziri; Ashley Woodbury; Dennis Fink; Kim Delbaere
Journal:  Eur Rev Aging Phys Act       Date:  2015-11-27       Impact factor: 3.878

7.  World Health Organization 2020 guidelines on physical activity and sedentary behaviour.

Authors:  Fiona C Bull; Salih S Al-Ansari; Stuart Biddle; Katja Borodulin; Matthew P Buman; Greet Cardon; Catherine Carty; Jean-Philippe Chaput; Sebastien Chastin; Roger Chou; Paddy C Dempsey; Loretta DiPietro; Ulf Ekelund; Joseph Firth; Christine M Friedenreich; Leandro Garcia; Muthoni Gichu; Russell Jago; Peter T Katzmarzyk; Estelle Lambert; Michael Leitzmann; Karen Milton; Francisco B Ortega; Chathuranga Ranasinghe; Emmanuel Stamatakis; Anne Tiedemann; Richard P Troiano; Hidde P van der Ploeg; Vicky Wari; Juana F Willumsen
Journal:  Br J Sports Med       Date:  2020-12       Impact factor: 13.800

8.  Web-based intervention to promote physical activity by sedentary older adults: randomized controlled trial.

Authors:  A Blair Irvine; Vicky A Gelatt; John R Seeley; Pamela Macfarlane; Jeff M Gau
Journal:  J Med Internet Res       Date:  2013-02-05       Impact factor: 5.428

9.  Interactive Cognitive-Motor Step Training Improves Cognitive Risk Factors of Falling in Older Adults - A Randomized Controlled Trial.

Authors:  Daniel Schoene; Trinidad Valenzuela; Barbara Toson; Kim Delbaere; Connie Severino; Jaime Garcia; Thomas A Davies; Frances Russell; Stuart T Smith; Stephen R Lord
Journal:  PLoS One       Date:  2015-12-16       Impact factor: 3.240

10.  The effect of eHealth-based falls prevention programmes on balance in people aged 65 years and over living in the community: protocol for a systematic review of randomised controlled trials.

Authors:  Meghan Ambrens; Anne Tiedemann; Kim Delbaere; Stephanie Alley; Corneel Vandelanotte
Journal:  BMJ Open       Date:  2020-01-15       Impact factor: 2.692

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