Literature DB >> 3567882

Klinefelter's syndrome and acute leukemia.

D E Horsman, J T Pantzar, F J Dill, D K Kalousek.   

Abstract

Klinefelter's syndrome is associated with an increased risk of certain types of cancer. A small number of reports have documented the occurrence of acute leukemia in these patients. Our review of 1200 consecutive patients investigated cytogenetically for actual or suspected hematologic malignancy revealed only one patient with acute leukemia and the 47,XXY syndrome. This finding suggests that the risk of acute leukemia in Klinefelter's patients is no greater than that of the general population.

Entities:  

Mesh：

Year:  1987        PMID： 3567882     DOI： 10.1016/0165-4608(87)90073-2

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  8 in total

Review 1.  Klinefelter syndrome and 47,XYY syndrome in children with B cell acute lymphoblastic leukaemia.

Authors:  Rachel E Rau; Andrew J Carroll; Nyla A Heerema; Lesley Arland; William L Carroll; Naomi J Winick; Elizabeth A Raetz; Mignon L Loh; Wenjian Yang; Mary V Relling; Yunfeng Dai; Meenakshi Devidas; Stephen P Hunger
Journal:  Br J Haematol       Date:  2016-07-19       Impact factor: 6.998

2.  RABGAP1L gene rearrangement resulting from a der(Y)t(Y;1)(q12;q25) in acute myeloid leukemia arising in a child with Klinefelter syndrome.

Authors:  Maria Cristina Roberti; Roberta La Starza; Cecilia Surace; Pietro Sirleto; Rita Maria Pinto; Valentina Pierini; Barbara Crescenzi; Cristina Mecucci; Adriano Angioni
Journal:  Virchows Arch       Date:  2009-01-28       Impact factor: 4.064

3.  Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases.

Authors:  M Bchir; W Ayed; H Ben Neji; O Kilani; S Kefi; M Zarrouk; H Guermani; S Hentati; A Amouri; B Meddeb
Journal:  Indian J Hematol Blood Transfus       Date:  2015-09-02       Impact factor: 0.900

4.  Congenital Aneuploidy in Klinefelter Syndrome with B-Cell Acute Lymphoblastic Leukemia Might Be Associated with Chromosomal Instability and Reduced Telomere Length.

Authors:  Eigil Kjeldsen
Journal:  Cancers (Basel)       Date:  2022-05-06       Impact factor: 6.575

5.  Acute myeloid leukemia in a patient with constitutional 47,XXY karyotype.

Authors:  Marla M Jalbut; Aliyah R Sohani; Paola Dal Cin; Robert P Hasserjian; Jenna A Moran; Andrew M Brunner; Amir T Fathi
Journal:  Leuk Res Rep       Date:  2015-04-22

6.  Chronic myeloid leukemia in case of Klinefelter syndrome.

Authors:  Vasundhara Chennuri; Rajesh Kashyap; Parag Tamhankar; Subha Phadke
Journal:  Indian J Hum Genet       Date:  2014-01

7.  Cancer incidence in men with Klinefelter syndrome.

Authors:  H Hasle; A Mellemgaard; J Nielsen; J Hansen
Journal:  Br J Cancer       Date:  1995-02       Impact factor: 7.640

8.  Angioimmunoblastic T-Cell Lymphoma in a Patient with Klinefelter Syndrome.

Authors:  Yong Tae Park; Chan-Ho Park; Mi Ae Bae; Hwa Sik Jung; Youn Im Lee; Ji-Hun Lim; Hee Jeong Cha; Min Jung Seo; Seol Hoon Park; Yunsuk Choi; Hawk Kim; Jae-Cheol Jo
Journal:  Am J Case Rep       Date:  2016-07-25
  8 in total

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