Literature DB >> 35674902

Exosomes as Carriers for Notch Molecules.

Guya Diletta Marconi1,2, Francesca Diomede3, Oriana Trubiani3, Cristina Porcheri2, Thimios A Mitsiadis4.   

Abstract

Exosomes are extracellular vesicles involved in cell-to-cell communication as well as extrusion of biological material. Using dental pulp stem cells culture as a model, we hereby describe a method for the packaging of Delta-like 4 (DLL4), a representative Notch ligand, into newly generated exosomes. We then provide methods of analysis to confirm the presence of Notch proteins and transcripts internalization and transport via exosomes.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Dental pulp stem cells; Exosomes; Extracellular vesicles; Notch pathway; Secretome

Mesh：

Substances：

Year:  2022        PMID： 35674902     DOI： 10.1007/978-1-0716-2201-8_16

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  12 in total

Review 1.  Notch signaling: cell fate control and signal integration in development.

Authors:  S Artavanis-Tsakonas; M D Rand; R J Lake
Journal:  Science       Date:  1999-04-30       Impact factor: 47.728

2.  Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

Authors:  T Ohtsuka; M Ishibashi; G Gradwohl; S Nakanishi; F Guillemot; R Kageyama
Journal:  EMBO J       Date:  1999-04-15       Impact factor: 11.598

Review 3.  Notch signaling: control of cell communication and cell fate.

Authors:  Eric C Lai
Journal:  Development       Date:  2004-03       Impact factor: 6.868

Review 4.  Stem cells living with a Notch.

Authors:  Ute Koch; Rajwinder Lehal; Freddy Radtke
Journal:  Development       Date:  2013-02       Impact factor: 6.868

Review 5.  Exosomes in developmental signalling.

Authors:  Ian John McGough; Jean-Paul Vincent
Journal:  Development       Date:  2016-07-15       Impact factor: 6.868

6.  Plasma membrane-derived extracellular microvesicles mediate non-canonical intercellular NOTCH signaling.

Authors:  Qiyu Wang; Quan Lu
Journal:  Nat Commun       Date:  2017-09-27       Impact factor: 14.919

7.  Three-dimensional printed PLA scaffold and human gingival stem cell-derived extracellular vesicles: a new tool for bone defect repair.

Authors:  Francesca Diomede; Agnese Gugliandolo; Paolo Cardelli; Ilaria Merciaro; Valeria Ettorre; Tonino Traini; Rossella Bedini; Domenico Scionti; Alessia Bramanti; Antonio Nanci; Sergio Caputi; Antonella Fontana; Emanuela Mazzon; Oriana Trubiani
Journal:  Stem Cell Res Ther       Date:  2018-04-13       Impact factor: 6.832

8.  Engineered Extracellular Vesicles From Human Periodontal-Ligament Stem Cells Increase VEGF/VEGFR2 Expression During Bone Regeneration.

Authors:  Jacopo Pizzicannella; Agnese Gugliandolo; Tiziana Orsini; Antonella Fontana; Alessia Ventrella; Emanuela Mazzon; Placido Bramanti; Francesca Diomede; Oriana Trubiani
Journal:  Front Physiol       Date:  2019-04-30       Impact factor: 4.566

9.  Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats.

Authors:  Faisal A Alzahrani; Mohammed A El-Magd; Ahmed Abdelfattah-Hassan; Ayman A Saleh; Islam M Saadeldin; Eman S El-Shetry; Abdelnaser A Badawy; Saleh Alkarim
Journal:  Stem Cells Int       Date:  2018-08-27       Impact factor: 5.443

10.  Extracellular vesicles in biological fluids. A biomarker of exposure to cigarette smoke and treatment with chemopreventive drugs.

Authors:  A Pulliero; L Pergoli; S LA Maestra; R T Micale; A Camoirano; V Bollati; A Izzotti; S DE Flora
Journal:  J Prev Med Hyg       Date:  2019-12-20
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