| Literature DB >> 35672921 |
Lindsey M Lavaysse1, Steven D Imrisek, Matthew Lee, Chandra Y Osborn, Ashley Hirsch, Jamillah Hoy-Rosas, Harpreet Nagra, Dan Goldner, Jeff Dachis, Lindsay E Sears.
Abstract
OBJECTIVE: Diabetes research on work productivity has been largely cross-sectional and retrospective, with only one known randomized controlled trial (RCT) published, to our knowledge. Secondary analysis of the Fit-One RCT tested the effect of One Drop's digital health program on workplace productivity outcomes, absenteeism, and presenteeism, for employees and specifically for older workers with type 2 diabetes.Entities:
Mesh:
Year: 2022 PMID: 35672921 PMCID: PMC9377500 DOI: 10.1097/JOM.0000000000002577
Source DB: PubMed Journal: J Occup Environ Med ISSN: 1076-2752 Impact factor: 2.306
Sample Descriptives
| Variable | Full Sample |
| ||
|---|---|---|---|---|
| All | Treatment | Control | ||
| Total | 125 | 63 | 62 | — |
| Sex, | 0.41 | |||
| Male | 53 (42) | 29 (46) | 24 (39) | — |
| Female | 72 (58) | 34 (54) | 38 (61) | — |
| Age, mean (SD), yr | 48.8 (8.0) | 48.3 (9.1) | 49.5 (6.8) | 0.40 |
| Race, | 0.30 | |||
| White | 88 (70) | 47 (75) | 41 (66) | — |
| Not White | 37 (30) | 16 (25) | 21 (34) | — |
| Insurance status, | 0.64 | |||
| Insured | 120 (96) | 61 (97) | 59 (95) | — |
| Uninsured | 5 (4) | 2 (3) | 3 (5) | — |
| Years diagnosed with T2D, mean (SD) | 8.9 (6.1) | 8.3 (5.9) | 9.5 (6.2) | 0.25 |
| Baseline HbA1c, mean (SD), % | 8.6 (1.5) | 8.7 (1.5) | 8.6 (1.4) | 0.80 |
HbA1c, hemoglobin A1c; SD, standard deviation; T2D, type 2 diabetes.
Logistic Regression Models for ITT and PP Analyses for Absenteeism
|
| OR (95% CI) |
| |
|---|---|---|---|
| Full sample | |||
| ITT: group effect on absenteeism | −0.212 | 0.81 (0.34–1.92) | 0.629 |
| PP: group effect on absenteeism | −0.376 | 0.69 (0.26–1.81) | 0.446 |
| 50-yr-and-older sample | |||
| ITT: group effect on absenteeism | −1.212 | 0.30 (0.07–1.27) | 0.101 |
| PP: group effect on absenteeism | −1.720 | 0.18 (0.03–1.03) | 0.053 |
The control group was used as the reference group. Baseline absenteeism was controlled for in all models.
CI, confidence interval; OR, odds ratio; PP, per-protocol; ITT, intent-to-treat.
Generalized Estimating Equations for ITT and PP Analyses of Presenteeism
| Variables | Control, Mean (SD) | Intervention, Mean (SD) | Group Effect | Interaction Effect | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
| Baseline | 3 mo | Baseline | 3 mo |
|
|
|
| |
| Full sample | ||||||||||
| ITT: presenteeism | 62 | 63 | 20.00 (23.61) | 25.32 (25.84) | 25.08 (23.27) | 20.32 (23.76) | −0.431 | 0.044* | — | — |
| PP: presenteeism | 59 | 58 | 20.17 (23.60) | 23.73 (24.91) | 23.97 (22.08) | 20.34 (23.39) | −0.258 | 0.232 | — | — |
| Age 50 yr and older | ||||||||||
| ITT: presenteeism | 31 | 26 | 22.58 (24.35) | 30.97 (27.61) | 26.54 (25.60) | 15.00 (24.04) | −2.007 | <0.001* | 0.029 | 0.006* |
| PP: presenteeism | 30 | 24 | 23.33 (24.40) | 29.00 (25.78) | 26.25 (25.16) | 15.00 (24.67) | −1.640 | 0.003* | 0.021 | 0.039* |
| Experienced presenteeism at baseline | ||||||||||
| ITT: presenteeism | 35 | 46 | 35.43 (20.91) | 36.86 (23.98) | 34.35 (20.51) | 25.87 (24.73) | −0.397 | 0.025* | — | — |
| PP: presenteeism | 34 | 43 | 35.00 (21.07) | 36.76 (24.34) | 32.33 (19.62) | 25.35 (24.33) | −0.395 | 0.032* | — | — |
| Age 50 yr and older and experienced presenteeism at baseline | ||||||||||
| ITT: presenteeism | 19 | 19 | 36.84 (20.83) | 40.53 (24.60) | 36.32 (23.14) | 20.00 (26.46) | −1.911 | 0.007* | 0.027 | 0.043* |
| PP: presenteeism | 19 | 18 | 36.84 (20.83) | 40.53 (24.60) | 35.00 (23.07) | 19.44 (27.11) | −1.919 | 0.006* | 0.027 | 0.043* |
Negative binomial distributions were used. The control group was used as the reference group. All models controlled for baseline presenteeism. Significant interactions between baseline presenteeism and group were held and interpreted; these are reported in the Interaction Effect column. Nonsignificant interactions were dropped from the final reported models.
PP, per-protocol; SD, standard deviation; ITT, intent-to-treat.
*Statistically significant effect at P < 0.05.
Per-Protocol GEE Analyses: Estimated Means of Follow-up Presenteeism
| Condition | Baseline Presenteeism |
| Mean, % |
|---|---|---|---|
| Age 50 yr and older | |||
| Control | Low | 15 | 16.0 |
| High | 12 | 48.7 | |
| Treatment | Low | 8 | 3.3 |
| High | 10 | 41.3 | |
| Age 50 yr and older and experienced presenteeism at baseline | |||
| Control | Low | 7 | 34.7 |
| High | 10 | 45.0 | |
| Treatment | Low | 8 | 8.4 |
| High | 6 | 44.8 | |
Low and high baseline presenteeism determined, respectively, by values below and above sample medians. Total N across each sample is not equal to the total N analyzed in PP analyses because participants with baseline presenteeism equal to their sample medians were pruned. Median baseline presenteeism was 20% for the 50-year-and-older sample and 30% for the 50-year-and-older and experienced presenteeism at baseline sample.
GEE, generalized estimating equation.
FIGURE 1Per-protocol analysis: baseline presenteeism and group interaction in the 50-year-and-older sample.
FIGURE 2Per-protocol analysis: baseline presenteeism and group interaction in the 50-year-and-older and experienced baseline presenteeism sample.