| Literature DB >> 3567206 |
Abstract
Bactopterin is a novel pterin occurring in bacterial molybdoenzymes as the organic portion of the molybdenum cofactor. Its structure is investigated here. The compound contains a single pterin ring and carries a side chain at carbon atom 6 of the pterin nucleus as indicated by the formation of pterin-6-carboxylic acid upon alkaline permanganate oxidation. Studies with phosphate-cleaving enzymes revealed the presence of two monophosphoric acid monoesters. The affinity of reduced bactopterin for thiol-Sepharose points to the presence of thiol(s) in active bactopterin.Entities:
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Year: 1987 PMID: 3567206 DOI: 10.1016/0167-4838(87)90040-9
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002