Literature DB >> 3566241

Single-dose ceftriaxone for chancroid.

M I Bowmer, H Nsanze, L J D'Costa, J Dylewski, L Fransen, P Piot, A R Ronald.   

Abstract

Men with genital ulcers that were culture positive for Haemophilus ducreyi were treated with intramuscular ceftriaxone and randomized to three different dose regimens. All but 1 of 50 men treated with 1 g of intramuscular ceftriaxone were cured. Similarly, 0.5 and 0.25 g cured 43 of 44 men and 37 of 38 men, respectively. A single dose of 250 mg of intramuscular ceftriaxone is an effective treatment for chancroid.

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Year:  1987        PMID： 3566241      PMCID： PMC174653          DOI： 10.1128/AAC.31.1.67

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Antimicrobial susceptibility of Haemophilus ducreyi.

Authors:  G W Hammond; C J Lian; J C Wilt; A R Ronald
Journal:  Antimicrob Agents Chemother       Date:  1978-04       Impact factor: 5.191

2.  Single-dose ceftriaxone therapy of gonococcal ophthalmia neonatorum.

Authors:  D A Haase; R A Nash; H Nsanze; L J D'Costa; L Fransen; P Piot; R C Brunham
Journal:  Sex Transm Dis       Date:  1986 Jan-Mar       Impact factor: 2.830

3.  Pharmacokinetics and tolerance of ceftriaxone in humans after single-dose intramuscular administration in water and lidocaine diluents.

Authors:  I H Patel; R E Weinfeld; J Konikoff; M Parsonnet
Journal:  Antimicrob Agents Chemother       Date:  1982-06       Impact factor: 5.191

Review 4.  The plasmids of Haemophilus ducreyi.

Authors:  P J McNicol; A R Ronald
Journal:  J Antimicrob Chemother       Date:  1984-12       Impact factor: 5.790

5.  Treatment of chancroid by clavulanic acid with amoxycillin in patients with beta-lactamase-positive Haemophilus ducreyi infection.

Authors:  M V Fast; H Nsanze; L J D'Costa; F A Plummer; P Karasira; I W Maclean; A R Ronald
Journal:  Lancet       Date:  1982-09-04       Impact factor: 79.321

6.  Comparison of the activities of ceftriaxone and penicillin G against experimentally induced syphilis in rabbits.

Authors:  R C Johnson; R F Bey; S J Wolgamot
Journal:  Antimicrob Agents Chemother       Date:  1982-06       Impact factor: 5.191

7.  Antimicrobial susceptibility and characterization of outer membrane proteins of Haemophilus ducreyi isolated in Thailand.

Authors:  D N Taylor; P Echeverria; S Hanchalay; C Pitarangsi; L Slootmans; P Piot
Journal:  J Clin Microbiol       Date:  1985-03       Impact factor: 5.948

8.  Trimethoprim sulphamoxole in the treatment of chancroid. Comparison of two single dose treatment regimens with a five day regimen.

Authors:  J Dylewski; H Nsanze; L D'Costa; L Slaney; A Ronald
Journal:  J Antimicrob Chemother       Date:  1985-07       Impact factor: 5.790

9.  Dose-ranging study of ceftriaxone for uncomplicated gonorrhea in men.

Authors:  H H Handsfield; V L Murphy; K K Holmes
Journal:  Antimicrob Agents Chemother       Date:  1981-12       Impact factor: 5.191

10.  Antimicrobial therapy of chancroid: effectiveness of erythromycin.

Authors:  F A Plummer; L J D'Costa; H Nsanze; I W Maclean; P Karasira; P Piot; M V Fast; A R Ronald
Journal:  J Infect Dis       Date:  1983-10       Impact factor: 5.226
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  6 in total

Review 1.  Antimicrobial susceptibility of Haemophilus ducreyi.

Authors:  Y Dangor; R C Ballard; S D Miller; H J Koornhof
Journal:  Antimicrob Agents Chemother       Date:  1990-07       Impact factor: 5.191

Review 2.  Treatment of chancroid.

Authors:  Y Dangor; R C Ballard; S D Miller; H J Koornhof
Journal:  Antimicrob Agents Chemother       Date:  1990-07       Impact factor: 5.191

Review 3.  Ceftriaxone. A reappraisal of its antibacterial activity and pharmacokinetic properties, and an update on its therapeutic use with particular reference to once-daily administration.

Authors:  R N Brogden; A Ward
Journal:  Drugs       Date:  1988-06       Impact factor: 9.546

4.  Comparison of the in vitro activities of various parenteral and oral antimicrobial agents against endemic Haemophilus ducreyi.

Authors:  K E Aldridge; C Cammarata; D H Martin
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

Review 5.  Clinical pharmacokinetics of ceftriaxone.

Authors:  J H Yuk; C H Nightingale; R Quintiliani
Journal:  Clin Pharmacokinet       Date:  1989-10       Impact factor: 6.447

Review 6.  Chancroid and Haemophilus ducreyi.

Authors:  S A Morse
Journal:  Clin Microbiol Rev       Date:  1989-04       Impact factor: 26.132
  6 in total

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