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Literature DB >> 6275788

Dose-ranging study of ceftriaxone for uncomplicated gonorrhea in men.

Abstract

Uncomplicated gonorrhea in men was successfully treated with ceftriaxone in single intramuscular doses of 125 mg (15 patients), 250 mg (16 patients), or 500 mg (15 patients). All 45 pretreatment gonococcal isolates tested were inhibited by </=0.016 mug of ceftriaxone per ml. Treatment was well tolerated and caused no toxicity.

Entities: Chemical Disease Species

Mesh：

Substances：
Ceftriaxone
Cefotaxime

Year: 1981 PMID： 6275788 PMCID： PMC181809 DOI： 10.1128/AAC.20.6.839

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

9 in total

1. Epidemiology and treatment of penicillinase-producing Neisseria gonorrhoeae.

Authors: P L Perine; R S Morton; P Piot; M S Siegel; G M Antal
Journal: Sex Transm Dis Date: 1979 Apr-Jun Impact factor: 2.830

2. Single doses of methacycline and doxycycline for gonorrhea: a cooperative study of the frequency and cause of treatment failure.

Authors: P J Wiesner; K K Holmes; P F Sparling; M J Maness; D M Bear; L T Gutman; W W Karney
Journal: J Infect Dis Date: 1973-04 Impact factor: 5.226

3. In vitro susceptibility of Haemophilus influenzae and neisseria gonorrhoeae to Ro 13-9904 in comparison with other beta-lactam antibiotics.

Authors: W S Ng; P Y Chau; K Arnold
Journal: Antimicrob Agents Chemother Date: 1981-05 Impact factor: 5.191

4. Pharmacokinetics of Ro 13-9904, a broad-spectrum cephalosporin.

Authors: M Seddon; R Wise; A P Gillett; R Livingston
Journal: Antimicrob Agents Chemother Date: 1980-08 Impact factor: 5.191

5. Antibacterial activity of ceftriaxone (Ro 13-9904), a beta-lactamase-stable cephalosporin.

Authors: H C Neu; N J Meropol; K P Fu
Journal: Antimicrob Agents Chemother Date: 1981-03 Impact factor: 5.191

6. In vitro antibacterial activity and susceptibility of the cephalosporin Ro 13-9904 to beta-lactamases.

Authors: K Shannon; A King; C Warren; I Phillips
Journal: Antimicrob Agents Chemother Date: 1980-08 Impact factor: 5.191

7. Iodometric detection of Haemophilus influenzae beta-lactamase: rapid presumptive test for ampicillin resistance.

Authors: B W Catlin
Journal: Antimicrob Agents Chemother Date: 1975-03 Impact factor: 5.191

8. Comparative in vitro studies of Ro 13-9904, a new cephalosporin derivative.

Authors: T C Eickhoff; J Ehret
Journal: Antimicrob Agents Chemother Date: 1981-03 Impact factor: 5.191

9. In vitro activity of Ro 13-9904, cefuroxime, cefoxitin, and ampicillin against Neisseria gonorrhoeae.

Authors: T T Yoshikawa; S A Shibata; P Herbert; P A Oill
Journal: Antimicrob Agents Chemother Date: 1980-08 Impact factor: 5.191

9 in total

14 in total

Dose-ranging study of ceftriaxone for uncomplicated gonorrhea in men.

1. Epidemiology and treatment of penicillinase-producing Neisseria gonorrhoeae.

2. Single doses of methacycline and doxycycline for gonorrhea: a cooperative study of the frequency and cause of treatment failure.

3. In vitro susceptibility of Haemophilus influenzae and neisseria gonorrhoeae to Ro 13-9904 in comparison with other beta-lactam antibiotics.

4. Pharmacokinetics of Ro 13-9904, a broad-spectrum cephalosporin.

5. Antibacterial activity of ceftriaxone (Ro 13-9904), a beta-lactamase-stable cephalosporin.

6. In vitro antibacterial activity and susceptibility of the cephalosporin Ro 13-9904 to beta-lactamases.

7. Iodometric detection of Haemophilus influenzae beta-lactamase: rapid presumptive test for ampicillin resistance.

8. Comparative in vitro studies of Ro 13-9904, a new cephalosporin derivative.

9. In vitro activity of Ro 13-9904, cefuroxime, cefoxitin, and ampicillin against Neisseria gonorrhoeae.

Review 1. Preparing for an era of untreatable gonorrhea.

2. In-vitro susceptibility of 400 isolates of Neisseria gonorrhoeae in Vancouver, 1982-84.

3. Comparative in vitro activity of Sch 29,482, a new oral penem, against Neisseria gonorrhoeae.

4. The potential uses of ceftriaxone.

Review 5. Role of cephalosporins in gonorrhoea and other sexually transmitted diseases.

6. Penicillinase-producing Neisseria gonorrhoeae in California. Report of a major outbreak and control recommendations.

Review 7. Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.

Review 8. The use of cephalosporins for gonorrhea: the impending problem of resistance.

9. Comparative in-vitro activity of selected new beta-lactam antimicrobials against Neisseria gonorrhoeae.

Review 10. Beta-lactams in sexually transmitted diseases: rationale for selection and dosing regimens.