Literature DB >> 35653137

The surprising difficulty of "simple" equilibrium binding measurements on ligand-gated ion channels.

Thomas R Middendorf1,2, Marcel P Goldschen-Ohm1.   

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Year:  2022        PMID: 35653137      PMCID: PMC9166280          DOI: 10.1085/jgp.202213177

Source DB:  PubMed          Journal:  J Gen Physiol        ISSN: 0022-1295            Impact factor:   4.000


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  9 in total

1.  Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation.

Authors:  H L Wang; A Auerbach; N Bren; K Ohno; A G Engel; S M Sine
Journal:  J Gen Physiol       Date:  1997-06       Impact factor: 4.086

2.  ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.

Authors:  J MONOD; J WYMAN; J P CHANGEUX
Journal:  J Mol Biol       Date:  1965-05       Impact factor: 5.469

3.  Unliganded gating of acetylcholine receptor channels.

Authors:  Prasad Purohit; Anthony Auerbach
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-29       Impact factor: 11.205

4.  Elapid neurotoxins and their mode of action.

Authors:  C Y Lee
Journal:  Clin Toxicol       Date:  1970-09       Impact factor: 4.467

5.  Scintillation proximity radioimmunoassay utilizing 125I-labeled ligands.

Authors:  S Udenfriend; L D Gerber; L Brink; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

6.  Probing function in ligand-gated ion channels without measuring ion transport.

Authors:  Nicole E Godellas; Claudio Grosman
Journal:  J Gen Physiol       Date:  2022-05-25       Impact factor: 4.000

7.  Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits.

Authors:  C J Hatton; C Shelley; M Brydson; D Beeson; D Colquhoun
Journal:  J Physiol       Date:  2003-01-24       Impact factor: 5.182

8.  Structural identifiability of equilibrium ligand-binding parameters.

Authors:  Thomas R Middendorf; Richard W Aldrich
Journal:  J Gen Physiol       Date:  2016-12-19       Impact factor: 4.086

9.  How to measure and evaluate binding affinities.

Authors:  Inga Jarmoskaite; Ishraq AlSadhan; Pavanapuresan P Vaidyanathan; Daniel Herschlag
Journal:  Elife       Date:  2020-08-06       Impact factor: 8.140

  9 in total

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