Literature DB >> 3564802

Synthesis of O2'-methyluridine, O2'-methylcytidine, N4,O2'-dimethylcytidine and N4,N4,O2'-trimethylcytidine from a common intermediate.

A Nyilas, J Chattopadhyaya.   

Abstract

A facile synthesis of the title compounds from a readily accessible precursor, 3',5'-O-bis-protected O4-(2-nitrophenyl)uridine, is described.

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Year:  1986        PMID： 3564802     DOI： 10.3891/acta.chem.scand.40b-0826

Source DB:  PubMed          Journal:  Acta Chem Scand B        ISSN： 0302-4369


  8 in total

1.  A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.

Authors:  E Wagner; B Oberhauser; A Holzner; H Brunar; G Issakides; G Schaffner; M Cotten; M Knollmüller; C R Noe
Journal:  Nucleic Acids Res       Date:  1991-11-11       Impact factor: 16.971

2.  Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues.

Authors:  Santosh K Mahto; Christine S Chow
Journal:  Bioorg Med Chem       Date:  2008-09-09       Impact factor: 3.641

3.  New synthetic routes to synthons suitable for 2'-O-allyloligoribonucleotide assembly.

Authors:  B S Sproat; A M Iribarren; R G Garcia; B Beijer
Journal:  Nucleic Acids Res       Date:  1991-02-25       Impact factor: 16.971

4.  Highly efficient chemical synthesis of 2'-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases.

Authors:  B S Sproat; A I Lamond; B Beijer; P Neuner; U Ryder
Journal:  Nucleic Acids Res       Date:  1989-05-11       Impact factor: 16.971

5.  Steric inhibition of human immunodeficiency virus type-1 Tat-dependent trans-activation in vitro and in cells by oligonucleotides containing 2'-O-methyl G-clamp ribonucleoside analogues.

Authors:  Stephen C Holmes; Andrey A Arzumanov; Michael J Gait
Journal:  Nucleic Acids Res       Date:  2003-06-01       Impact factor: 16.971

6.  New synthetic routes to protected purine 2'-O-methylriboside-3'-O-phosphoramidites using a novel alkylation procedure.

Authors:  B S Sproat; B Beijer; A Iribarren
Journal:  Nucleic Acids Res       Date:  1990-01-11       Impact factor: 16.971

7.  Synthesis and use of labelled nucleoside phosphoramidite building blocks bearing a reporter group: biotinyl, dinitrophenyl, pyrenyl and dansyl.

Authors:  A Roget; H Bazin; R Teoule
Journal:  Nucleic Acids Res       Date:  1989-10-11       Impact factor: 16.971

8.  The RNA Modification Database, RNAMDB: 2011 update.

Authors:  William A Cantara; Pamela F Crain; Jef Rozenski; James A McCloskey; Kimberly A Harris; Xiaonong Zhang; Franck A P Vendeix; Daniele Fabris; Paul F Agris
Journal:  Nucleic Acids Res       Date:  2010-11-10       Impact factor: 16.971
  8 in total

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