Literature DB >> 35605882

Proceedings from the Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Immune and Cellular Therapy in Multiple Myeloma.

Sarah A Holstein1, Fotis Asimakopoulos2, Abdel Kareem Azab3, Giada Bianchi4, Manisha Bhutani5, Leslie A Crews2, Tom Cupedo6, Hannah Giles7, Sarah Gooding8, Jens Hillengass9, Lukas John10, Shari Kaiser11, Lydia Lee12, Kylee Maclachlan13, Marcelo C Pasquini14, Flavia Pichiorri15, Nina Shah16, Monica Shokeen3, Brian R Shy16, Eric L Smith17, Raluca Verona18, Saad Z Usmani13, Philip L McCarthy9.   

Abstract

The Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup conducted a workshop on Immune and Cellular Therapy in Multiple Myeloma on January 7, 2022. This workshop included presentations by basic, translational, and clinical researchers with expertise in plasma cell dyscrasias. Four main topics were discussed: platforms for myeloma disease evaluation, insights into pathophysiology, therapeutic target and resistance mechanisms, and cellular therapy for multiple myeloma. Here we provide a comprehensive summary of these workshop presentations.
Copyright © 2022 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  CAR T cell; Imaging; Multiple myeloma; Resistance; Tumor microenvironment

Mesh:

Year:  2022        PMID: 35605882      PMCID: PMC9357156          DOI: 10.1016/j.jtct.2022.05.019

Source DB:  PubMed          Journal:  Transplant Cell Ther        ISSN: 2666-6367


  75 in total

1.  Summary of the Second Annual BMT CTN Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.

Authors:  Sarah A Holstein; J Christine Ye; Alan Howard; Manisha Bhutani; Nicole Gormley; Theresa Hahn; Jens Hillengass; Amrita Krishnan; C Ola Landgren; Nikhil C Munshi; Stefania Oliva; Roger G Owen; Marcelo C Pasquini; Noemi Puig; Niels Weinhold; Katja Weisel; Philip L McCarthy
Journal:  Biol Blood Marrow Transplant       Date:  2018-11-05       Impact factor: 5.742

Review 2.  International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders.

Authors:  Jens Hillengass; Saad Usmani; S Vincent Rajkumar; Brian G M Durie; María-Victoria Mateos; Sagar Lonial; Cristina Joao; Kenneth C Anderson; Ramón García-Sanz; Eloísa Riva; Juan Du; Niels van de Donk; Jesús G Berdeja; Evangelos Terpos; Elena Zamagni; Robert A Kyle; Jesús San Miguel; Hartmut Goldschmidt; Sergio Giralt; Shaji Kumar; Noopur Raje; Heinz Ludwig; Enrique Ocio; Rik Schots; Hermann Einsele; Fredrik Schjesvold; Wen-Ming Chen; Niels Abildgaard; Brea C Lipe; Dominik Dytfeld; Baldeep Mona Wirk; Matthew Drake; Michele Cavo; Juan José Lahuerta; Suzanne Lentzsch
Journal:  Lancet Oncol       Date:  2019-06       Impact factor: 41.316

3.  Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation.

Authors:  Elena Zamagni; Francesca Patriarca; Cristina Nanni; Beatrice Zannetti; Emanuela Englaro; Annalisa Pezzi; Paola Tacchetti; Silvia Buttignol; Giulia Perrone; Annamaria Brioli; Lucia Pantani; Carolina Terragna; Francesca Carobolante; Michele Baccarani; Renato Fanin; Stefano Fanti; Michele Cavo
Journal:  Blood       Date:  2011-09-06       Impact factor: 22.113

4.  P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment.

Authors:  Abdel Kareem Azab; Phong Quang; Feda Azab; Costas Pitsillides; Brian Thompson; Triona Chonghaile; John T Patton; Patricia Maiso; Val Monrose; Antonio Sacco; Hai T Ngo; Ludmila M Flores; Charles P Lin; John L Magnani; Andrew L Kung; Anthony Letai; Ruben Carrasco; Aldo M Roccaro; Irene M Ghobrial
Journal:  Blood       Date:  2011-11-16       Impact factor: 22.113

Review 5.  Summary of the 2019 Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.

Authors:  Sarah A Holstein; Alan Howard; David Avigan; Manisha Bhutani; Adam D Cohen; Luciano J Costa; Madhav V Dhodapkar; Francesca Gay; Nicole Gormley; Damian J Green; Jens Hillengass; Neha Korde; Zihai Li; Sham Mailankody; Paola Neri; Samir Parekh; Marcelo C Pasquini; Noemi Puig; G David Roodman; Mehmet Kemal Samur; Nina Shah; Urvi A Shah; Qian Shi; Andrew Spencer; Vera J Suman; Saad Z Usmani; Philip L McCarthy
Journal:  Biol Blood Marrow Transplant       Date:  2020-06-24       Impact factor: 5.742

6.  Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency.

Authors:  David N Nguyen; Theodore L Roth; P Jonathan Li; Peixin Amy Chen; Ryan Apathy; Murad R Mamedov; Linda T Vo; Victoria R Tobin; Daniel Goodman; Eric Shifrut; Jeffrey A Bluestone; Jennifer M Puck; Francis C Szoka; Alexander Marson
Journal:  Nat Biotechnol       Date:  2019-12-09       Impact factor: 54.908

7.  Comparison of CD38-Targeted α- Versus β-Radionuclide Therapy of Disseminated Multiple Myeloma in an Animal Model.

Authors:  Megan Minnix; Vikram Adhikarla; Enrico Caserta; Erasmus Poku; Russell Rockne; John E Shively; Flavia Pichiorri
Journal:  J Nucl Med       Date:  2020-10-30       Impact factor: 10.057

8.  Inhibition of P-Selectin and PSGL-1 Using Humanized Monoclonal Antibodies Increases the Sensitivity of Multiple Myeloma Cells to Bortezomib.

Authors:  Barbara Muz; Feda Azab; Pilar de la Puente; Scott Rollins; Richard Alvarez; Ziad Kawar; Abdel Kareem Azab
Journal:  Biomed Res Int       Date:  2015-10-11       Impact factor: 3.411

9.  Reprogramming human T cell function and specificity with non-viral genome targeting.

Authors:  Theodore L Roth; Cristina Puig-Saus; Ruby Yu; Eric Shifrut; Julia Carnevale; P Jonathan Li; Joseph Hiatt; Justin Saco; Paige Krystofinski; Han Li; Victoria Tobin; David N Nguyen; Michael R Lee; Amy L Putnam; Andrea L Ferris; Jeff W Chen; Jean-Nicolas Schickel; Laurence Pellerin; David Carmody; Gorka Alkorta-Aranburu; Daniela Del Gaudio; Hiroyuki Matsumoto; Montse Morell; Ying Mao; Min Cho; Rolen M Quadros; Channabasavaiah B Gurumurthy; Baz Smith; Michael Haugwitz; Stephen H Hughes; Jonathan S Weissman; Kathrin Schumann; Jonathan H Esensten; Andrew P May; Alan Ashworth; Gary M Kupfer; Siri Atma W Greeley; Rosa Bacchetta; Eric Meffre; Maria Grazia Roncarolo; Neil Romberg; Kevan C Herold; Antoni Ribas; Manuel D Leonetti; Alexander Marson
Journal:  Nature       Date:  2018-07-11       Impact factor: 49.962

10.  Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report.

Authors:  David L Murray; Noemi Puig; Sigurdur Kristinsson; Saad Z Usmani; Angela Dispenzieri; Giada Bianchi; Shaji Kumar; Wee Joo Chng; Roman Hajek; Bruno Paiva; Anders Waage; S Vincent Rajkumar; Brian Durie
Journal:  Blood Cancer J       Date:  2021-02-01       Impact factor: 11.037

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