| Literature DB >> 35604691 |
Gwen T Lapham1,2, Theresa E Matson1,2, David S Carrell1, Jennifer F Bobb1, Casey Luce1, Malia M Oliver1, Udi E Ghitza3, Clarissa Hsu1, Kendall C Browne4, Ingrid A Binswanger5,6, Cynthia I Campbell7, Andrew J Saxon4, Ryan Vandrey8, Gillian L Schauer9, Rosalie Liccardo Pacula10,11, Michael A Horberg12, Steffani R Bailey13, Erin A McClure14, Katharine A Bradley15.
Abstract
Importance: Patients who use cannabis for medical reasons may benefit from discussions with clinicians about health risks of cannabis and evidence-based treatment alternatives. However, little is known about the prevalence of medical cannabis use in primary care and how often it is documented in patient electronic health records (EHR). Objective: To estimate the primary care prevalence of medical cannabis use according to confidential patient survey and to compare the prevalence of medical cannabis use documented in the EHR with patient report. Design, Setting, and Participants: This study is a cross-sectional survey performed in a large health system that conducts routine cannabis screening in Washington state where medical and nonmedical cannabis use are legal. Among 108 950 patients who completed routine cannabis screening (between March 28, 2019, and September 12, 2019), 5000 were randomly selected for a confidential survey about cannabis use, using stratified random sampling for frequency of past-year use and patient race and ethnicity. Data were analyzed from November 2020 to December 2021. Exposures: Survey measures of patient-reported past-year cannabis use, medical cannabis use (ie, explicit medical use), and any health reason(s) for use (ie, implicit medical use). Main Outcomes and Measures: Survey data were linked to EHR data in the year before screening. EHR measures included documentation of explicit and/or implicit medical cannabis use. Analyses estimated the primary care prevalence of cannabis use and compared EHR-documented with patient-reported medical cannabis use, accounting for stratified sampling and nonresponse.Entities:
Mesh:
Substances:
Year: 2022 PMID: 35604691 PMCID: PMC9127557 DOI: 10.1001/jamanetworkopen.2022.11677
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Figure. Flow Diagram of Study Sample
Patients who were Kaiser Permanente Washington employees, needed an interpreter, lived outside Washington State, were recently deceased, or opted out of EHR research were excluded. Other racial and ethnic minoritized groups includes American Indian, Alaskan Native, Asian, Pacific Islander, Black/African American, Hispanic/Latinx, and Multiracial. EHR indicates electronic health record.
Characteristics of the Primary Care Sample
| Characteristic | Primary care sample (N = 1688) | |
|---|---|---|
| Patients, % (SE) | Patients, No. | |
| Sex | ||
| Male | 44.1 (4.1) | 827 |
| Female | 55.9 (4.1) | 861 |
| Age, y | ||
| 18-25 | 9.1 (2.4) | 246 |
| 26-35 | 17.2 (3.1) | 479 |
| 36-44 | 15.0 (3.2) | 222 |
| 45-64 | 31.0 (3.9) | 423 |
| ≥65 | 27.7 (3.4) | 318 |
| Race | ||
| American Indian/Alaskan Native | 0.1 (<1) | 13 |
| Asian/Pacific Islander | 9.1 (2.3) | 88 |
| Black/African American | 4.6 (1.7) | 135 |
| Multiracial | 3.6 (1.5) | 109 |
| Other/unknown | 8.4 (2.5) | 158 |
| White | 74.2 (3.7) | 1184 |
| Hispanic ethnicity | 3.3 (1.0) | 174 |
| Insurance | ||
| Medicaid/subsidized | 6.0 (1.8) | 189 |
| Medicare | 27.1 (3.4) | 323 |
| Commercial | 64.9 (3.7) | 1059 |
| Unknown | 2.0 (0.8) | 124 |
| Education | ||
| Less than high school | 2.8 (1.5) | 34 |
| High school graduate or GED | 9.9 (2.3) | 282 |
| Some college | 38.6 (4.0) | 665 |
| 4-y college degree | 13.4 (2.5) | 378 |
| >4-y college degree | 34.4 (4.0) | 316 |
| Missing | 0.9 (0.8) | 10 |
| Marital status | ||
| Married | 57.0 (4.1) | 695 |
| Widowed | 3.0 (1.3) | 43 |
| Divorced/separated | 9.2 (2.4) | 166 |
| Single/never married | 24.1 (3.5) | 505 |
| Living with partner | 5.8 (1.5) | 271 |
| Missing | 0.9 (0.8) | 8 |
| Employment status | ||
| Employed | ||
| Full-time | 55.4 (4.1) | 988 |
| Part-time | 12.6 (2.9) | 152 |
| School/vocational | 1.7 (1.1) | 47 |
| Retired | 22.0 (3.1) | 298 |
| Homemaker | 3.4 (1.5) | 38 |
| Unemployed | 0.8 (0.2) | 58 |
| Disabled | 2.4 (1.3) | 73 |
| Other | 0.8 (0.6) | 28 |
| Residence | ||
| Own | 67.7 (3.8) | 883 |
| Rent | 28.9 (3.7) | 694 |
| Living with friends/family | 2.1 (1.1) | 82 |
| No permanent residence | 0.4 (0.1) | 21 |
| Missing | 0.9 (0.8) | 6 |
| Frequency of past-year cannabis use (survey) | ||
| None | 61.2 (3.7) | 99 |
| Less than monthly | 14.6 (2.5) | 99 |
| Monthly | 5.8 (1.6) | 118 |
| Weekly | 7.3 (1.4) | 376 |
| Daily or almost daily | 11.1 (1.7) | 996 |
Percentage was calculated from survey data weighted for sampling and nonresponse rates for eligible primary care sample.
Number was calculated from unweighted survey data.
Patients are provided the option to indicate other when choosing among 1 or more race categories at appointing or check-in. Patients who indicated more than 1 race are reported as multiracial.
Indicates data from survey; all other data are from electronic health record.
Prevalence of Primary Care Patient Medical Cannabis Use According to Measures From a Survey and Electronic Health Record Documentation
| Medical cannabis use measure | Patients, % (95% CI) |
|---|---|
| Patient survey responses | |
| Use of cannabis in past year was for | |
| Nonmedical reasons | 12.3 (9.0-15.6) |
| Medical reasons | 15.5 (101.3-19.8) |
| Both medical and nonmedical reasons | 10.9 (8.4-13.4) |
| Did not use cannabis in past year | 61.2 (55.3-67.2) |
| Patient report of explicit medical cannabis use | 26.5 (21.6-31.3) |
| Use of cannabis in past year to help manage any of the following | |
| Pain | 28.4 (23.2-33.7) |
| Sleep | 19.0 (15.1-22.9) |
| Stress | 19.0 (14.8-23.2) |
| Worry or anxiety | 14.6 (11.3-17.9) |
| Depression or sadness | 9.6 (7.2-11.9) |
| Muscle spasm | 8.2 (5.5-10.8) |
| Nausea or vomiting | 6.1 (4.1-8.2) |
| Focus or concentration | 3.6 (2.4-4.8) |
| Appetite | 3.4 (2.6-4.2) |
| Other | 3.2 (1.6-4.7) |
| Seizures | 0.1 (0.1-0.2) |
| None | 3.7 (2.0-5.4) |
| Patient report of implicit medical cannabis use | 35.1 (29.3-40.8) |
| EHR documented measure | |
| Medical cannabis use (explicit and/or implicit) | 4.8 (3.4-6.2) |
Abbreviation: EHR, electronic health record.
Percentage was calculated from survey data weighted for sampling and nonresponse rates to estimate eligible primary care sample, and adjusted for age, sex, race, ethnicity, insurance, education, marital, employment, and residential status, as well as note-days for the EHR-documented measure.
Includes report of medical only and both medical and nonmedical reasons for cannabis use.
Includes any above reasons for use except none.
EHR-documented medical cannabis use was assessed in year before the index cannabis screen documented in the EHR.
Performance of EHR-Documented Medical Cannabis Use When Compared With Patient Report of Medical Use Among Primary Care Patients
| Patient report | EHR-documented medical cannabis use, % (95% CI) | |||
|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | |
| Explicit medical use | 10.0 (4.4-15.6) | 97.1 (94.4-99.8) | 55.4 (28.3-82.6) | 75.0 (68.9-81.1) |
| Implicit medical use | 8.4 (4.1-12.7) | 97.2 (94.1-1.00) | 61.9 (33.4-90.4) | 66.3 (59.3-73.3) |
Abbreviations: EHR, electronic health record; NPV, negative predictive value; PPV, positive predictive value.
Percentage was calculated from survey data weighted for sampling and nonresponse rates for eligible primary care sample.
Cannabis use was determined by patient report on a survey.