| Literature DB >> 35600146 |
Edgar Mandeng Ma Linwa1,2, Odette Berline Sigha2,3, Angelique Jacquie Djeumen Touka2, Charlotte Eposse Ekoube2,4, Esther Eleonore Ngo Linwa3, Michael Ngenge Budzi1,5, Martin Geh Meh1, Henry Fomukong Nzozone1, Emmanuel Armand Kouotou6, Anne-Cecile Zoung Kanyi Bissek6.
Abstract
Introduction: With the advent of COVID-19, a highly infectious viral pandemic, first declared in Cameroon in March 2020, access to expert dermatology care was postulated to decrease. We carried out a descriptive study to understand the epidemiology of skin diseases amongst patients consulting at an outpatient dermatology clinic and its variations with the onset of COVID-19.Entities:
Year: 2022 PMID: 35600146 PMCID: PMC9111051 DOI: 10.1002/ski2.113
Source DB: PubMed Journal: Skin Health Dis ISSN: 2690-442X
Distribution of grouped dermatological diseases amongst different age groups
| Diagnosis (International Classification of Diseases 11th Edition: ICD0‐11 CODES) | Age (years | Number (%) | |||
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| 0–17 years | 18–40 years | 41–50 years | 51 years and older | ||
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| Fungal infections (EA60.Z) | 147 | 371 | 90 | 109 | 717 |
| Bacterial infections (1B21.2Z. 1C44. 1B7Y) | 161 | 159 | 43 | 39 | 402 |
| Scabies (1G04) | 126 | 230 | 42 | 55 | 453 |
| Viral infections (EA3Z, EH10, 1F0Z,1A95 1E76, 1E80) | 123 | 113 | 19 | 26 | 281 |
| Filaria, and larva migrans (1F66.Z, 1F68.2) | 4 | 6 | 2 | 4 | 16 |
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| Eczema (EA80) | 194 | 325 | 97 | 144 | 760 |
| Lichen simplex (EA83) | 25 | 103 | 35 | 36 | 199 |
| Erythroderma (EB10) | 6 | 7 | 1 | 10 | 24 |
| Xerosis cutis and ictyosis (ED54, EC20.Z) | 7 | 20 | 6 | 14 | 47 |
| Others (EA81.Z, EA86.0) | 79 | 35 | 6 | 7 | 127 |
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| Pityriasis rosea (EA10) | 57 | 94 | 10 | 4 | 161 |
| Psoriasis (EA90.Z) | 2 | 25 | 9 | 27 | 63 |
| Prurigo (EC91.Z) | 321 | 97 | 29 | 23 | 470 |
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| Urticaria (EB05) | 29 | 125 | 24 | 18 | 196 |
| Lymphoedema (BD93.Z) | 0 | 3 | 6 | 10 | 19 |
| Others (2E81.2Y, 2F23.0, EA86.0, BD74.1Z, BD74.2) | 30 | 17 | 5 | 6 | 58 |
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| 10 | 16 | 9 | 5 |
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| 4 | 37 | 9 | 27 |
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| 2 | 6 | 11 | 6 |
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Note: A p‐value <0.05 was considered significant.
Gender differences in top 10 single diagnoses at outpatient dermatology consultations
| Skin disease (ICD‐11 CODE) | Male | Female | Total |
|---|---|---|---|
| Acne (ED80.Z) | 205 (9.3%) | 643 (17.2%) | 848 (14.3%) |
| Eczema (EA80) | 277 (12.6%) | 482 (12.9%) | 760 (12.8%) |
| Prurigo (EC91.Z) | 197 (8.9%) | 273 (7.3%) | 470 (7.9%) |
| Scabies (1G04) | 188 (8.5%) | 264 (7.1%) | 453 (7.6%) |
| Dermatophyte infections (1F28.Z) | 96 (4.4%) | 158 (4.2%) | 254 (4.3%) |
| Lichen simplex (EA83) | 83 (3.8%) | 116 (3.1%) | 199 (3.3%) |
| Urticaria (EB05) | 53 (2.4%) | 143 (3.8%) | 196 (3.3%) |
| Pityriasis versicolour (1F2D.0) | 78 (4.4%) | 112 (3.0%) | 190 (3.2%) |
| Pityriasis rosea (EA10) | 45 (2.0%) | 120 (3.2%) | 165 (2.8%) |
| Folliculitis/pseudofolliculitis (ED9Y) | 81 (3.7%) | 73 (2.0%) | 154 (2.6%) |
Pattern of change of commonest dermatological diseases in the COVID‐19 era
| Skin disease (ICD‐11 CODE) | Pre‐COVID‐19 era ( | COVID‐19 era ( | Total | OR (95% CI) |
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|---|---|---|---|---|---|
| Acne (ED80.Z) | 498 (13.8%) | 350 (15.0%) | 848 (14.3%) | 1.092 (0.963–1.239) | 0.172 |
| Eczema (EA80) | 468 (12.9%) | 292 (12.5%) | 760 (12.8%) | 0.970 (0.846–1.112) | 0.691 |
| Prurigo (EC91.Z) | 296 (8.2%) | 174 (7.5%) | 470 (7.9%) | 0.914 (0.763–1.094) | 0.350 |
| Scabies (1G04) | 222 (6.1%) | 231 (9.9%) | 453 (7.6%) | 1.617 (1.355–1.930) |
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| Dermatophyte infections (1F28.Z) | 159 (4.4%) | 95 (4.1%) | 254 (4.3%) | 0.929 (0.724–1.191) | 0.599 |
| Lichen simplex (EA83) | 99 (2.7%) | 100 (4.3%) | 199 (3.3%) | 1.570 (1.195–2.062) |
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| Urticaria (EB05) | 126 (3.5%) | 70 (3.0%) | 196 (3.3%) | 0.863 (0.643–1.151) | 0.334 |
| Pityriasis versicolour (1F2D.0) | 121 (3.3%) | 69 (3.0%) | 190 (3.2%) | 0.886 (0.662–1.186) | 0.450 |
| Pityriasis Rosea (EA10) | 113 (3.1%) | 52 (2.2%) | 165 (2.8%) | 0.715 (0.517–0.989) |
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| Folliculitis/pseudofolliculi tis (ED9Y) | 90 (2.5%) | 64 (2.7%) | 154 (2.6%) | 1.105 (0.806–1.516) | 0.559 |
Note: A p‐value <0.05 was considered significant.
Multivariate analysis of prevalent dermatoses in the general population
| Skin disease (ICD‐11 CODE) | Pre‐COVID‐19 era ( | COVID‐19 era ( | Total | aOR (95% CI) |
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| Scabies (1G04) | 222 (6.1%) | 231 (9.9%) | 453 (7.6%) | 1.640 (1.235–2.177) |
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| Lichen simplex (EA83) | 99 (2.7%) | 100 (4.3%) | 199 (3.3%) | 0.753 (0.539–1.051) | 0.095 NS |
| Pityriasis Rosea (EA10) | 113 (3.1%) | 52 (2.2%) | 165 (2.8%) | 1.697 (1.400–2.057) |
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Note: A p‐value <0.05 was considered significant.
FIGURE 1Variations in consultations over the months before and after COVID‐19's first reported case in Cameroon
Top diagnoses amongst elderly patients (>50 years) considered risk group for COVID mortality
| Skin disease (ICD‐11 CODE) | Pre‐COVID‐19 era ( | COVID‐19 era ( | Total ( | OR (95% CI) |
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| Eczema (EA80) | 75 (15.7%) | 69 (21.5%) | 144 (18.0%) | 1.373 (1.022–1.844) |
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| Acne (ED80.Z) | 11 (2.3%) | 5 (1.6%) | 16 (2.0%) | 0.678 (0.238–1.934) | 0.609 |
| Prurigo (EC91.Z) | 17 (3.5%) | 6 (1.7%) | 23 (2.9%) | 0.527 (0.210–1.321) | 0.198 |
| Scabies (1G04) | 22 (4.6%) | 33 (10.3%) | 55 (6.9%) | 2.238 (1.330–3.767) |
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| Pityriasis versicolour (1F2D.0) | 9 (1.9%) | 1 (0.3%) | 10 (1.3%) | 0.166 (0.021–1.302) | 0.057 |
| Dermatophyte infections (1F28.Z) | 26 (5.4%) | 21 (6.5%) | 47 (5.9%) | 1.205 (0.690–2.105) | 0.541 |
| Lichen simplex (EA83) | 21 (4.4%) | 15 (4.7%) | 36 (4.5%) | 1.066 (0.558–2.036) | 0.863 |
| Urticaria (EB05) | 9 (1.9%) | 9 (2.8%) | 18 (2.3%) | 1.492 (0.599–3.718) | 0.467 |
| Pityriasis rosea (EA10) | 4 (0.8%) | 0 (0%) | 4 (1.9%) | NA | NA |
| Folliculitis/pseudofolliculitis (ED9Y) | 7 (1.5%) | 8 (2.5%) | 15 (1.9%) | 1.705 (0.625–4.657) | 0.301 |
Note: A p‐value <0.05 was considered significant.
Multivariate analyses of prevalent dermatoses amongst patients above 50 years
| Skin disease (ICD‐11 CODE) | Pre‐COVID‐19 era ( | COVID‐19 era ( | Total ( | OR (95% CI) |
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| Eczema (EA80) | 75 (15.7%) | 69 (21.5%) | 144 (18.0%) | 1.605 (1.112–2.316) |
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| Scabies (1G04) | 22 (4.6%) | 33 (10.3%) | 55 (6.9%) | 2.616 (1.488–4.601) |
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Note: A p‐value <0.05 was considered significant.