Literature DB >> 355890

DNA sequence for a low-level promoter of the lac repressor gene and an 'up' promoter mutation.

M P Calos.   

Abstract

The promoter for a weakly expressed constitutive gene, the lactose repressor gene (lacI), has been sequenced, along with an 'up' promoter mutation Iq. The 10-fold enhancement in I expression found in Iq is the result of a single base change at position -35. To facilitate the sequencing, the lacI gene was cloned in a small plasmid.

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Year:  1978        PMID： 355890     DOI： 10.1038/274762a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  85 in total

1.  Role of the CheW protein in bacterial chemotaxis: overexpression is equivalent to absence.

Authors:  D A Sanders; B Mendez; D E Koshland
Journal:  J Bacteriol       Date:  1989-11       Impact factor: 3.490

2.  Role of CheW protein in coupling membrane receptors to the intracellular signaling system of bacterial chemotaxis.

Authors:  J D Liu; J S Parkinson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

3.  SYNTHETIC BIOLOGY. Emergent genetic oscillations in a synthetic microbial consortium.

Authors:  Ye Chen; Jae Kyoung Kim; Andrew J Hirning; Krešimir Josić; Matthew R Bennett
Journal:  Science       Date:  2015-08-28       Impact factor: 47.728

4.  Adaptation of a luciferase gene reporter and lac expression system to Borrelia burgdorferi.

Authors:  Jon S Blevins; Andrew T Revel; Alexandra H Smith; Gulnaz N Bachlani; Michael V Norgard
Journal:  Appl Environ Microbiol       Date:  2007-01-12       Impact factor: 4.792

5.  Enhanced bacterial protein expression during auto-induction obtained by alteration of lac repressor dosage and medium composition.

Authors:  Paul G Blommel; Katie J Becker; Petar Duvnjak; Brian G Fox
Journal:  Biotechnol Prog       Date:  2007-05-17

6.  Comparison of deterministic and stochastic models of the lac operon genetic network.

Authors:  Michail Stamatakis; Nikos V Mantzaris
Journal:  Biophys J       Date:  2009-02       Impact factor: 4.033

7.  Isocitrate dehydrogenase kinase/phosphatase: aceK alleles that express kinase but not phosphatase activity.

Authors:  T Ikeda; D C LaPorte
Journal:  J Bacteriol       Date:  1991-03       Impact factor: 3.490

8.  Distinctive patterns of translational reinitiation in the lac repressor mRNA: bridging of long distances by out-of-frame translation and RNA secondary structure, effects of primary sequence.

Authors:  R J Matteson; S J Biswas; D A Steege
Journal:  Nucleic Acids Res       Date:  1991-07-11       Impact factor: 16.971

9.  Regulatory region of the divergent Klebsiella pneumoniae lac operon.

Authors:  W E Buvinger; M Riley
Journal:  J Bacteriol       Date:  1985-09       Impact factor: 3.490

10.  Regulatory regions of two transport operons under nitrogen control: nucleotide sequences.

Authors:  C F Higgins; G F Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205
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