Literature DB >> 35582462

A Methodology for Remote Microwave Sterilization Applicable to the Coronavirus and Other Pathogens Using Retrodirective Antenna Arrays.

Konstantinos Kossenas1, Symon K Podilchak1, Davide Comite2, Pascual D Hilario Re3, George Goussetis3, Sumanth K Pavuluri3, Samantha J Griffiths4, Robert J Chadwick5, Chao Guo5, Nico Bruns5, Christine Tait-Burkard4, Jurgen G Haas4, Marc P Y Desmulliez3.   

Abstract

This paper describes an innovative remote surface sterilization approach applicable to the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The process is based on the application of a liquid film on the surface or object under sterilization (OUS). A beacon signal is used to self-steer the transmitted power from the designed retrodirective antenna array (RDA) towards the OUS using circularly polarized fields; then, the sterilization is completed by raising and maintaining the required temperature for a certain time. Results suggest that the process takes 5 minutes or less for an angular coverage range over 60 degrees whilst abiding by the relevant safety protocols. This paper also models the power incident onto the OUS, providing consistent results with full-wave simulations. A practical RDA system is developed using a 2 × 1 microstrip patch array operating at 2.5 GHz and tested through the positioning of a representative target surface. Measurements, developed by sampling the power transmitted by the heterodyne RDA, are reported for various distances and angles, operating in the near-field of the system. To further validate the methodology, an additional experiment investigating virus deactivation through microwave heating was also developed. Measurements have been performed with an open cavity microwave oven on the Coronavirus (strain 229E) and egg white protein in a cuvette. This demonstrates that the temperature increases of aqueous films up to 70 [Formula: see text]C by remote microwave-induced heat can denature proteins and deactivate viruses. Possible applications of the method include sterilization of ambulances, medical equipment, and internet of things (IoT) devices.

Entities:  

Keywords:  COVID-19; SARS-CoV-2; medical devices; microwave heating; near field; remote sterilization; retrodirective array

Year:  2021        PMID: 35582462      PMCID: PMC8956366          DOI: 10.1109/JERM.2021.3077110

Source DB:  PubMed          Journal:  IEEE J Electromagn RF Microw Med Biol        ISSN: 2469-7249


  9 in total

1.  Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity.

Authors:  Luisa Cervantes-Barragan; Roland Züst; Reinhard Maier; Sophie Sierro; Jozef Janda; Frederic Levy; Daniel Speiser; Pedro Romero; Pierre-Simon Rohrlich; Burkhard Ludewig; Volker Thiel
Journal:  MBio       Date:  2010-09-14       Impact factor: 7.867

2.  Sterilization of heat-resistant instruments with infrared radiation.

Authors:  Victor Hugo Mata-Portuguez; Leonor Sánchez Pérez; Enrique Acosta-Gío
Journal:  Infect Control Hosp Epidemiol       Date:  2002-07       Impact factor: 3.254

3.  Guidelines for Limiting Exposure to Electromagnetic Fields (100 kHz to 300 GHz).

Authors: 
Journal:  Health Phys       Date:  2020-05       Impact factor: 1.316

4.  Efficient Structure Resonance Energy Transfer from Microwaves to Confined Acoustic Vibrations in Viruses.

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Journal:  Sci Rep       Date:  2015-12-09       Impact factor: 4.379

Review 5.  Using heat to kill SARS-CoV-2.

Authors:  John P Abraham; Brian D Plourde; Lijing Cheng
Journal:  Rev Med Virol       Date:  2020-07-02       Impact factor: 11.043

6.  Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.

Authors:  Neeltje van Doremalen; Trenton Bushmaker; Dylan H Morris; Myndi G Holbrook; Amandine Gamble; Brandi N Williamson; Azaibi Tamin; Jennifer L Harcourt; Natalie J Thornburg; Susan I Gerber; James O Lloyd-Smith; Emmie de Wit; Vincent J Munster
Journal:  N Engl J Med       Date:  2020-03-17       Impact factor: 91.245

Review 7.  Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination.

Authors:  J A Otter; C Donskey; S Yezli; S Douthwaite; S D Goldenberg; D J Weber
Journal:  J Hosp Infect       Date:  2015-10-03       Impact factor: 3.926

8.  Survival of surrogate coronaviruses in water.

Authors:  Lisa Casanova; William A Rutala; David J Weber; Mark D Sobsey
Journal:  Water Res       Date:  2009-02-10       Impact factor: 11.236

9.  Susceptibility of SARS-CoV-2 to UV irradiation.

Authors:  Christiane Silke Heilingloh; Ulrich Wilhelm Aufderhorst; Leonie Schipper; Ulf Dittmer; Oliver Witzke; Dongliang Yang; Xin Zheng; Kathrin Sutter; Mirko Trilling; Mira Alt; Eike Steinmann; Adalbert Krawczyk
Journal:  Am J Infect Control       Date:  2020-08-04       Impact factor: 2.918

  9 in total
  1 in total

1.  Microwave resonant absorption of SARS-CoV-2 viruses.

Authors:  Peng-Jui Wang; Yu-Hao Pang; Sheng-Yu Huang; Jun-Tung Fang; Sui-Yuan Chang; Shin-Ru Shih; Tian-Wei Huang; Yi-Jan Chen; Chi-Kuang Sun
Journal:  Sci Rep       Date:  2022-07-22       Impact factor: 4.996

  1 in total

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