Literature DB >> 35579754

Primary ambulatory thromboprophylaxis in patients with pancreatic cancer receiving chemotherapy: hope or hype?

Thura Win Htut1, Kyaw Zin Thein2, Kyaw Lwin Aung3, Thein Hlaing Oo4.   

Abstract

Thrombosis is the second leading cause of death in cancer patients. Patients with pancreatic cancer (PC) have a very high risk of developing venous thromboembolism (VTE). Even though primary ambulatory thromboprophylaxis (PATP) could decrease this risk, there are uncertain issues with regard to the choice and dose of anticoagulants, duration of anticoagulant therapy, and patient selection criteria. In addition, the current practice guidelines on PATP in PC patients are equivocal. This review critically appraises the evidence on the use of PATP in PC patients receiving chemotherapy.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Chemotherapy; Pancreatic cancer; Primary ambulatory thromboprophylaxis; Risk scoring systems; Venous thromboembolism

Mesh：

Substances：

Year:  2022        PMID： 35579754     DOI： 10.1007/s00520-022-07138-8

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN： 0941-4355            Impact factor:   3.359


  28 in total

1.  A modified Khorana risk assessment score for venous thromboembolism in cancer patients receiving chemotherapy: the Protecht score.

Authors:  Melina Verso; Giancarlo Agnelli; Sandro Barni; Giampietro Gasparini; Roberto LaBianca
Journal:  Intern Emerg Med       Date:  2012-05-01       Impact factor: 3.397

2.  Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study.

Authors:  J A Heit; M D Silverstein; D N Mohr; T M Petterson; W M O'Fallon; L J Melton
Journal:  Arch Intern Med       Date:  2000-03-27

3.  Malignancies, prothrombotic mutations, and the risk of venous thrombosis.

Authors:  Jeanet W Blom; Carine J M Doggen; Susanne Osanto; Frits R Rosendaal
Journal:  JAMA       Date:  2005-02-09       Impact factor: 56.272

4.  Prediction of venous thromboembolism in cancer patients.

Authors:  Cihan Ay; Daniela Dunkler; Christine Marosi; Alexandru-Laurentiu Chiriac; Rainer Vormittag; Ralph Simanek; Peter Quehenberger; Christoph Zielinski; Ingrid Pabinger
Journal:  Blood       Date:  2010-09-09       Impact factor: 22.113

5.  Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy.

Authors:  A A Khorana; C W Francis; E Culakova; N M Kuderer; G H Lyman
Journal:  J Thromb Haemost       Date:  2007-03       Impact factor: 5.824

6.  Development and validation of a predictive model for chemotherapy-associated thrombosis.

Authors:  Alok A Khorana; Nicole M Kuderer; Eva Culakova; Gary H Lyman; Charles W Francis
Journal:  Blood       Date:  2008-01-23       Impact factor: 22.113

7.  2019 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer.

Authors:  Dominique Farge; Corinne Frere; Jean M Connors; Cihan Ay; Alok A Khorana; Andres Munoz; Benjamin Brenner; Ajay Kakkar; Hanadi Rafii; Susan Solymoss; Dialina Brilhante; Manuel Monreal; Henri Bounameaux; Ingrid Pabinger; James Douketis
Journal:  Lancet Oncol       Date:  2019-09-03       Impact factor: 41.316

8.  Risk and timing of neutropenic events in adult cancer patients receiving chemotherapy: the results of a prospective nationwide study of oncology practice.

Authors:  Jeffrey Crawford; David C Dale; Nicole M Kuderer; Eva Culakova; Marek S Poniewierski; Debra Wolff; Gary H Lyman
Journal:  J Natl Compr Canc Netw       Date:  2008-02       Impact factor: 11.908

9.  Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update.

Authors:  Nigel S Key; Alok A Khorana; Nicole M Kuderer; Kari Bohlke; Agnes Y Y Lee; Juan I Arcelus; Sandra L Wong; Edward P Balaban; Christopher R Flowers; Charles W Francis; Leigh E Gates; Ajay K Kakkar; Mark N Levine; Howard A Liebman; Margaret A Tempero; Gary H Lyman; Anna Falanga
Journal:  J Clin Oncol       Date:  2019-08-05       Impact factor: 44.544

Review 10.  Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis.

Authors:  Freesia Horsted; Joe West; Matthew J Grainge
Journal:  PLoS Med       Date:  2012-07-31       Impact factor: 11.069
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