Kelly E Knickelbein1, Mary E Lassaline2, Soohyun Kim1, Sara M Thomasy2,3. 1. Veterinary Medical Teaching Hospital, University of California-Davis, Davis, California, USA. 2. Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California, USA. 3. Department of Ophthalmology and Vision Science, University of California-Davis, Davis, California, USA.
Abstract
BACKGROUND: The iridocorneal angle (ICA) is the major pathway of aqueous humour outflow from the anterior chamber of the eye. Ultrasound biomicroscopy (UBM) has been utilised to characterise the morphology of this drainage pathway in numerous species. UBM may allow for early recognition of aqueous humour outflow obstructions in horses, allowing for earlier recognition of risk for glaucoma, a vision-threatening and painful disease. UBM morphology of the normal equine ICA has yet to be described. OBJECTIVES: To determine the ultrasonographic morphology of the equine ICA by UBM in standing sedated horses. STUDY DESIGN: In vivo experimental study. METHODS: Thirty healthy adult horses underwent UBM of the ICA at four locations (superior, temporal, inferior, nasal) of each eye utilising standing sedation, topical anaesthesia and auriculopalpebral perineural anaesthesia. Anatomic structures were defined on ultrasound images through comparison to published histologic photomicrographs of the equine ICA. RESULTS: Ultrasound imaging of the ICA at all four locations was easily performed in standing, sedated horses. High-resolution images of the ICA allowed for identification of the pectinate ligament, corneoscleral trabecular meshwork (TM), uveal TM and supraciliary TM. MAIN LIMITATIONS: Pupil size was midrange in all eyes, but was not strictly controlled. Lighting conditions not controlled. Various breeds included. CONCLUSION: In vivo UBM of the equine ICA is feasible and provides high-resolution images of the structures of the aqueous humour outflow pathway.
BACKGROUND: The iridocorneal angle (ICA) is the major pathway of aqueous humour outflow from the anterior chamber of the eye. Ultrasound biomicroscopy (UBM) has been utilised to characterise the morphology of this drainage pathway in numerous species. UBM may allow for early recognition of aqueous humour outflow obstructions in horses, allowing for earlier recognition of risk for glaucoma, a vision-threatening and painful disease. UBM morphology of the normal equine ICA has yet to be described. OBJECTIVES: To determine the ultrasonographic morphology of the equine ICA by UBM in standing sedated horses. STUDY DESIGN: In vivo experimental study. METHODS: Thirty healthy adult horses underwent UBM of the ICA at four locations (superior, temporal, inferior, nasal) of each eye utilising standing sedation, topical anaesthesia and auriculopalpebral perineural anaesthesia. Anatomic structures were defined on ultrasound images through comparison to published histologic photomicrographs of the equine ICA. RESULTS: Ultrasound imaging of the ICA at all four locations was easily performed in standing, sedated horses. High-resolution images of the ICA allowed for identification of the pectinate ligament, corneoscleral trabecular meshwork (TM), uveal TM and supraciliary TM. MAIN LIMITATIONS: Pupil size was midrange in all eyes, but was not strictly controlled. Lighting conditions not controlled. Various breeds included. CONCLUSION: In vivo UBM of the equine ICA is feasible and provides high-resolution images of the structures of the aqueous humour outflow pathway.
Authors: Margaret C Li Puma; Kate S Freeman; Allison M Cleymaet; Samantha L Pederson; Amanda C Crawford; Shelby C Dinger; Lance C Li Puma; Matthew S Johnston Journal: Vet Ophthalmol Date: 2019-04-01 Impact factor: 1.644
Authors: Thomas Dulaurent; Frédéric Goulle; Alice Dulaurent; Marielle Mentek; Robert Louis Peiffer; Pierre-François Isard Journal: Vet Ophthalmol Date: 2011-04-19 Impact factor: 1.644
Authors: Thomas Boillot; Serge G Rosolen; Thomas Dulaurent; Frédéric Goulle; Philippe Thomas; Pierre-François Isard; Thierry Azoulay; Stéphanie Lafarge-Beurlet; Mike Woods; Sylvie Lavillegrand; Ivana Ivkovic; Nathalie Neveux; José-Alain Sahel; Serge Picaud; Nicolas Froger Journal: PLoS One Date: 2014-11-07 Impact factor: 3.240