Literature DB >> 3555886

Chymotrypsin: molecular and catalytic properties.

W Appel.   

Abstract

A review on the peptide hydrolase chymotrypsin gives some characteristics concerning the structure, specificity, mechanism of activation from its precursor and catalytic activity. Problems of the active sites, allosteric alterations, changes of conformation, different behaviour against types of substrates, and suggested kinetics are shown in some detail. Finally, the diagnostic role of this serine proteinase is mentioned.

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Year:  1986        PMID： 3555886     DOI： 10.1016/s0009-9120(86)80002-9

Source DB:  PubMed          Journal:  Clin Biochem        ISSN： 0009-9120            Impact factor:   3.281


  25 in total

1.  Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivatives.

Authors:  Adriana L Andrade; Kenneth Melich; G Gregory Whatley; Sarah R Kirk; Jeffrey W Karpen
Journal:  J Med Chem       Date:  2011-06-14       Impact factor: 7.446

2.  N-Methylation of Amino Acids in Gelatinase Biosynthesis-Activating Pheromone Identifies Key Site for Stability Enhancement with Retention of the Enterococcus faecalis fsr Quorum Sensing Circuit Response.

Authors:  Dominic N McBrayer; Brooke K Gantman; Yftah Tal-Gan
Journal:  ACS Infect Dis       Date:  2019-04-19       Impact factor: 5.084

3.  Characterization of low affinity Fcγ receptor biotinylation under controlled reaction conditions by mass spectrometry and ligand binding analysis.

Authors:  Karin P M Geuijen; David F Egging; Stefanie Bartels; Jan Schouten; Richard B Schasfoort; Michel H Eppink
Journal:  Protein Sci       Date:  2016-08-19       Impact factor: 6.725

4.  Mercury(II) binds to both of chymotrypsin's histidines, causing inhibition followed by irreversible denaturation/aggregation.

Authors:  Amanda Stratton; Matthew Ericksen; Travis V Harris; Nick Symmonds; Todd P Silverstein
Journal:  Protein Sci       Date:  2017-01-14       Impact factor: 6.725

5.  Learning protein constitutive motifs from sequence data.

Authors:  Jérôme Tubiana; Simona Cocco; Rémi Monasson
Journal:  Elife       Date:  2019-03-12       Impact factor: 8.140

6.  PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids.

Authors:  Chien-Chi Lin; Asad Raza; Han Shih
Journal:  Biomaterials       Date:  2011-09-14       Impact factor: 12.479

7.  Crystallization and preliminary X-ray analysis of crinumin, a chymotrypsin-like glycosylated serine protease with thrombolytic and antiplatelet activity.

Authors:  Kunwar Awaneesh Singh; M V Jagannadham; G R K Rao; Patrick H N Celie
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2011-11-25

Review 8.  Critical care pharmacotherapy. A review.

Authors:  M Tryba; P J Kulka
Journal:  Drugs       Date:  1993-03       Impact factor: 9.546

9.  α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats.

Authors:  Asha Rani; Subhadeep Roy; Manjari Singh; Uma Devi; Rajnish K Yadav; Swetlana Gautam; Jitendra K Rawat; Mohd Nazam Ansari; Abdulaziz S Saeedan; Anand Prakash; Gaurav Kaithwas
Journal:  Inflammopharmacology       Date:  2016-09-26       Impact factor: 4.473

10.  The characterization of the Phlebotomus papatasi transcriptome.

Authors:  J Abrudan; M Ramalho-Ortigão; S O'Neil; G Stayback; M Wadsworth; M Bernard; D Shoue; S Emrich; P Lawyer; S Kamhawi; E D Rowton; M J Lehane; P A Bates; J G Valenzeula; C Tomlinson; E Appelbaum; D Moeller; B Thiesing; R Dillon; S Clifton; N F Lobo; R K Wilson; F H Collins; M A McDowell
Journal:  Insect Mol Biol       Date:  2013-02-07       Impact factor: 3.585
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