Emily A Croce1,2, Paul J Rathouz3, Fabiana C P S Lopes4, Maria Leszczynska1, Lucia Z Diaz1,4,5, Moise L Levy1,4,5, Jennifer S Ruth1,4,5, Pooja Varshney1,5, Lynn Rew2, Elizabeth C Matsui1,3,5. 1. Dell Children's Medical Group, Ascension Seton, Austin, Texas, USA. 2. The University of Texas at Austin School of Nursing, Austin, Texas, USA. 3. Department of Population Health, Dell Medical School at The University of Texas at Austin, Austin, Texas, USA. 4. Department of Internal Medicine, Dell Medical School at The University of Texas at Austin, Austin, Texas, USA. 5. Department of Pediatrics, Dell Medical School at The University of Texas at Austin, Austin, Texas, USA.
Abstract
BACKGROUND/ OBJECTIVES: We sought to quantify the reliability and validity of remote atopic dermatitis (AD) severity assessment using the Eczema Area and Severity Index (EASI) applied to caregiver-provided photos (p-EASI) and videos (v-EASI). METHODS: Children (0-17 years) with a physician diagnosis of AD were recruited. Caregivers took photos and a video of their child's skin. A clinician scored in-person EASI on the same day, then p-EASI and v-EASI for each participant 10 days or more between ratings. Two additional clinicians scored p-EASI and v-EASI. Lin's concordance correlation coefficient (CCC) was employed to assess criterion validity using in-person EASI as the gold standard. Intraclass correlation coefficients (ICCs) were calculated to assess interrater reliability of p-EASI and v-EASI. RESULTS: Fifty racially and ethnically diverse children (age [mean ± SD]: 4.3 ± 4.4 years; 42% female) with a range of AD severity (EASI: 6.3 ± 6.4) and Fitzpatrick skin types (1-2: 9%; 3-4: 60%; 5-6: 31%) were enrolled and received in-person EASI assessment. Fifty had p-EASI and 49 had v-EASI by the same in-person rater, and by two additional raters. The CCC and ICC for p-EASI were 0.89, 95% CI [0.83, 0.95] and 0.81, 95% CI [0.71, 0.89], respectively. The CCC and ICC for v-EASI were 0.75, 95% CI [0.63, 0.88] and 0.69, 95% CI [0.51, 0.81], respectively. CONCLUSIONS: In this diverse population with a range of skin tones, p-EASI showed good criterion validity and good interrater reliability. v-EASI showed moderate to good criterion validity and moderate interrater reliability. Both may be reliable and valid options for remote AD severity assessment.
BACKGROUND/ OBJECTIVES: We sought to quantify the reliability and validity of remote atopic dermatitis (AD) severity assessment using the Eczema Area and Severity Index (EASI) applied to caregiver-provided photos (p-EASI) and videos (v-EASI). METHODS: Children (0-17 years) with a physician diagnosis of AD were recruited. Caregivers took photos and a video of their child's skin. A clinician scored in-person EASI on the same day, then p-EASI and v-EASI for each participant 10 days or more between ratings. Two additional clinicians scored p-EASI and v-EASI. Lin's concordance correlation coefficient (CCC) was employed to assess criterion validity using in-person EASI as the gold standard. Intraclass correlation coefficients (ICCs) were calculated to assess interrater reliability of p-EASI and v-EASI. RESULTS: Fifty racially and ethnically diverse children (age [mean ± SD]: 4.3 ± 4.4 years; 42% female) with a range of AD severity (EASI: 6.3 ± 6.4) and Fitzpatrick skin types (1-2: 9%; 3-4: 60%; 5-6: 31%) were enrolled and received in-person EASI assessment. Fifty had p-EASI and 49 had v-EASI by the same in-person rater, and by two additional raters. The CCC and ICC for p-EASI were 0.89, 95% CI [0.83, 0.95] and 0.81, 95% CI [0.71, 0.89], respectively. The CCC and ICC for v-EASI were 0.75, 95% CI [0.63, 0.88] and 0.69, 95% CI [0.51, 0.81], respectively. CONCLUSIONS: In this diverse population with a range of skin tones, p-EASI showed good criterion validity and good interrater reliability. v-EASI showed moderate to good criterion validity and moderate interrater reliability. Both may be reliable and valid options for remote AD severity assessment.
Authors: C Y Zhao; E Y Hao; D D Oh; B S Daniel; L K Martin; J C Su; M Rodrigues; D F Murrell Journal: Br J Dermatol Date: 2017-03-01 Impact factor: 9.302
Authors: Meagan E Hughes; Hilary Aralis; Kevin W Bruhn; Jonathan Cotliar; Noah Craft; Ilana J DeLuca; Reyhaneh Hamidi; Kathy Nguyen; Mayha Patel; Vishal A Patel; Howard Sofen; Belinda H Tan; Consuelo V David Journal: J Am Acad Dermatol Date: 2019-01-29 Impact factor: 11.527
Authors: Zarqa Ali; Kristina Melbardis Joergensen; Anders Daniel Andersen; Andrei Chiriac; Theis Bjerre-Christensen; Ionela Manole; Ana-Maria Dutei; Irina Deaconescu; Alina Suru; Adina Serban; Ari Pall Isberg; Priyanka Dahiya; Simon Francis Thomsen; John Robert Zibert Journal: JMIR Form Res Date: 2021-05-25