| Literature DB >> 35505924 |
Wei-Hai Chen1, Qi-Wen Chen1, Qian Chen2, Chunyan Cui3, Shun Duan4, Yongyuan Kang5, Yang Liu6, Yun Liu7,8, Wali Muhammad5, Shiqun Shao9,10, Chengqiang Tang11, Jinqiang Wang7,8, Lei Wang12, Meng-Hua Xiong13, Lichen Yin14, Kuo Zhang12, Zhanzhan Zhang6, Xu Zhen15, Jun Feng1, Changyou Gao5, Zhen Gu7,8, Chaoliang He16, Jian Ji5, Xiqun Jiang15, Wenguang Liu3, Zhuang Liu2, Huisheng Peng11, Youqing Shen9,10, Linqi Shi6, Xuemei Sun11, Hao Wang12, Jun Wang13, Haihua Xiao17, Fu-Jian Xu4, Zhiyuan Zhong18,19, Xian-Zheng Zhang1, Xuesi Chen16.
Abstract
Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation. © Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2022.Entities:
Keywords: biocompatibility; bioimaging and biosensing; biomedical polymer; cancer therapy; cytotoxicity; drug delivery; nanomedicine; regenerative medicine; tissue engineering
Year: 2022 PMID: 35505924 PMCID: PMC9050484 DOI: 10.1007/s11426-022-1243-5
Source DB: PubMed Journal: Sci China Chem ISSN: 1869-1870 Impact factor: 10.138