Literature DB >> 35505019

Photodynamic Treatments for Disseminated Cancer Metastases Using Fiber-Optic Technologies.

Eric M Kercher1,2,3, Bryan Q Spring4,5,6.   

Abstract

Tumor-targeted and -activatable photosensitizer delivery platforms are creating new opportunities to develop photodynamic therapy (PDT) of metastatic disease. This is possible by confining the activity of the photosensitizing chemical (i.e., the PDT agent) to the tumor in combination with diffuse near-infrared light irradiation for wide-field treatment. This chapter outlines protocols and research tools for preclinical development of light-activated therapies of cancer metastases using advanced-stage ovarian cancer as a model system. We also describe an in vivo molecular imaging approach that uniquely enables tracking intraperitoneal micrometastatic burden and responses to treatment using fluorescence microendoscopy.
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Cancer metastases; Fluorescence microendoscopy; Molecular imaging; Mouse models; Ovarian cancer; Peritoneal carcinomatosis; Photodynamic therapy; Photoimmunotherapy; Targeted therapy

Mesh：

Substances：

Year:  2022        PMID： 35505019     DOI： 10.1007/978-1-0716-2099-1_14

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  51 in total

1.  Photodynamic therapy: a mitochondrial inducer of apoptosis.

Authors:  D Kessel; Y Luo
Journal:  Cell Death Differ       Date:  1999-01       Impact factor: 15.828

2.  A phase II trial of intraperitoneal photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis.

Authors:  Stephen M Hahn; Douglas L Fraker; Rosemarie Mick; James Metz; Theresa M Busch; Debbie Smith; Timothy Zhu; Carmen Rodriguez; Andreea Dimofte; Francis Spitz; Mary Putt; Stephen C Rubin; Chandrakala Menon; Hsing-Wen Wang; Daniel Shin; Arjun Yodh; Eli Glatstein
Journal:  Clin Cancer Res       Date:  2006-04-15       Impact factor: 12.531

3.  Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells.

Authors:  M L Agarwal; M E Clay; E J Harvey; H H Evans; A R Antunez; N L Oleinick
Journal:  Cancer Res       Date:  1991-11-01       Impact factor: 12.701

4.  Death pathways associated with photodynamic therapy.

Authors:  David Kessel
Journal:  Med Laser Appl       Date:  2006-11-15

Review 5.  The role of photodynamic therapy in overcoming cancer drug resistance.

Authors:  Bryan Q Spring; Imran Rizvi; Nan Xu; Tayyaba Hasan
Journal:  Photochem Photobiol Sci       Date:  2015-04-09       Impact factor: 3.982

6.  Ovarian cancer development and metastasis.

Authors:  Ernst Lengyel
Journal:  Am J Pathol       Date:  2010-07-22       Impact factor: 4.307

Review 7.  Surveillance procedures for patients treated for epithelial ovarian cancer: a review of the literature.

Authors:  A Gadducci; S Cosio; P Zola; F Landoni; T Maggino; E Sartori
Journal:  Int J Gynecol Cancer       Date:  2007 Jan-Feb       Impact factor: 3.437

8.  Phase I study of debulking surgery and photodynamic therapy for disseminated intraperitoneal tumors.

Authors:  T F DeLaney; W F Sindelar; Z Tochner; P D Smith; W S Friauf; G Thomas; L Dachowski; J W Cole; S M Steinberg; E Glatstein
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-02-15       Impact factor: 7.038

Review 9.  The biology of ovarian cancer: new opportunities for translation.

Authors:  Robert C Bast; Bryan Hennessy; Gordon B Mills
Journal:  Nat Rev Cancer       Date:  2009-06       Impact factor: 60.716

Review 10.  Ovarian cancer metastasis: integrating insights from disparate model organisms.

Authors:  Honami Naora; Denise J Montell
Journal:  Nat Rev Cancer       Date:  2005-05       Impact factor: 60.716
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