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Literature DB >> 35490076

Feeling the heat: how chaperones deal with biomolecular condensates.

Abstract

Yoo et al. have uncovered the minimal requirements of chaperone-mediated dispersal of Pab1 biomolecular condensates. These studies expand our understanding of the uniqueness of co-chaperones and add to our fundamental understanding of the heat shock response in cells. Published by Elsevier Ltd.

Entities: Chemical

Keywords: aggregation; biomolecular condensation; chaperones; heat shock; phase separation

Mesh：

Substances：
Molecular Chaperones

Year: 2022 PMID： 35490076 PMCID： PMC9586463 DOI： 10.1016/j.tibs.2022.04.008

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 14.264

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References

10 in total

Review 1. Cellular sensing by phase separation: Using the process, not just the products.

Authors: Haneul Yoo; Catherine Triandafillou; D Allan Drummond
Journal: J Biol Chem Date: 2019-03-15 Impact factor: 5.157

Review 2. Not quite the SSAme: unique roles for the yeast cytosolic Hsp70s.

Authors: Sarah K Lotz; Laura E Knighton; Gary W Jones; Andrew W Truman
Journal: Curr Genet Date: 2019-04-24 Impact factor: 3.886

Review 3. Recent advances in understanding catalysis of protein folding by molecular chaperones.

Authors: David Balchin; Manajit Hayer-Hartl; F Ulrich Hartl
Journal: FEBS Lett Date: 2020-06-12 Impact factor: 4.124

4. Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response.

Authors: Joshua A Riback; Christopher D Katanski; Jamie L Kear-Scott; Evgeny V Pilipenko; Alexandra E Rojek; Tobin R Sosnick; D Allan Drummond
Journal: Cell Date: 2017-03-09 Impact factor: 41.582

5. Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress.

Authors: Edward W J Wallace; Jamie L Kear-Scott; Evgeny V Pilipenko; Michael H Schwartz; Pawel R Laskowski; Alexandra E Rojek; Christopher D Katanski; Joshua A Riback; Michael F Dion; Alexander M Franks; Edoardo M Airoldi; Tao Pan; Bogdan A Budnik; D Allan Drummond
Journal: Cell Date: 2015-09-10 Impact factor: 41.582

Review 6. Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system.

Authors: Jacob Verghese; Jennifer Abrams; Yanyu Wang; Kevin A Morano
Journal: Microbiol Mol Biol Rev Date: 2012-06 Impact factor: 11.056

Feeling the heat: how chaperones deal with biomolecular condensates.

Review 1. Cellular sensing by phase separation: Using the process, not just the products.

Review 2. Not quite the SSAme: unique roles for the yeast cytosolic Hsp70s.

Review 3. Recent advances in understanding catalysis of protein folding by molecular chaperones.

4. Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response.

5. Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress.

Review 6. Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system.

7. Chaperones directly and efficiently disperse stress-triggered biomolecular condensates.

Review 8. Post-translational modifications of Hsp70 family proteins: Expanding the chaperone code.

9. Differential effects of Ydj1 and Sis1 on Hsp70-mediated clearance of stress granules in Saccharomyces cerevisiae.

10. Transient intracellular acidification regulates the core transcriptional heat shock response.