Literature DB >> 35486357

Modifiable Determinants of Satisfaction with Intravitreal Treatment in Patients with Neovascular Age-Related Macular Degeneration.

Paola S Calles-Monar1, María R Sanabria2, Ana M Alonso-Tarancon2, Rosa M Coco-Martin3,4, Agustín Mayo-Iscar5.   

Abstract

BACKGROUND: The success of intravitreal treatment for neovascular age-related macular degeneration (nAMD) depends on maximal adherence to treatment, which in turn requires patient satisfaction.
OBJECTIVE: The aim of this study was to assess the factors associated with nAMD patient satisfaction to implement actions to improve treatment experiences and increase adherence.
DESIGN: This was a prospective, observational, analytical, cross-sectional study.
SUBJECTS: Our study included 100 consecutive nAMD patients under intravitreal treatment for at least 1 year.
METHODS: Patients completed the Macular Disease Treatment Satisfaction Questionnaire (MacTSQ) and the EuroQol Visual Analog Scale (EQ VAS). A logistic regression was estimated to model the low values of the satisfaction score (MacTSQ < 50).
RESULTS: The mean age of patients was 82.1 ± 7.8 years and 62% were female. Males (p = 0.002) and patients who improved their visual acuity (p = 0.004) were more satisfied, while patients who received a higher number of injections (p = 0.036) and treatment in both eyes (p = 0.001) were less satisfied. Higher health-related quality of life was related to higher satisfaction. The sensitivity and specificity of the predictive model were 75.8% and 76.1%, respectively. Factors independently associated with low satisfaction were female sex (odds ratio [OR] 6.84), going to the clinic alone (OR 8.51), longer duration of treatment (OR 0.62), receiving treatment in both eyes (OR 3.54), and suffering a decline in visual acuity (OR 3.30). The questionnaire revealed patients' needs for more information and injection points closer to their homes.
CONCLUSIONS: Well-defined areas for improvement were identified, i.e. to improve the information offered to each patient, to incorporate new long-acting drugs, and to establish locations for injection services in peripheral areas.
© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

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Year:  2022        PMID: 35486357     DOI: 10.1007/s40266-022-00937-y

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  26 in total

1.  Prevalence of age-related macular degeneration in elderly Caucasians: the Tromsø Eye Study.

Authors:  Maja G Erke; Geir Bertelsen; Tunde Peto; Anne K Sjølie; Haakon Lindekleiv; Inger Njølstad
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2.  Disease Burden in the Treatment of Age-Related Macular Degeneration: Findings From a Time-and-Motion Study.

Authors:  Jonathan L Prenner; Lawrence S Halperin; Catherine Rycroft; Susan Hogue; Zinaria Williams Liu; Robert Seibert
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3.  Treatment satisfaction of patients with neovascular age-related macular degeneration treated with anti-vascular endothelial growth factor agents.

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6.  Clinical classification of age-related macular degeneration.

Authors:  Frederick L Ferris; C P Wilkinson; Alan Bird; Usha Chakravarthy; Emily Chew; Karl Csaky; SriniVas R Sadda
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Review 7.  Experiences of patients undergoing anti-VEGF treatment for neovascular age-related macular degeneration: a systematic review.

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8.  Reduced occurrence of severe visual impairment after introduction of anti-Vascular Endothelial Growth Factor in wet age-related macular degeneration - a population- and register-based study from northern Sweden.

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Review 9.  Age-related macular degeneration.

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10.  Treatment satisfaction of patients undergoing ranibizumab therapy for neovascular age-related macular degeneration in a real-life setting.

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Journal:  Patient Prefer Adherence       Date:  2016-05-26       Impact factor: 2.711

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