Literature DB >> 26142721

Disease Burden in the Treatment of Age-Related Macular Degeneration: Findings From a Time-and-Motion Study.

Jonathan L Prenner1, Lawrence S Halperin2, Catherine Rycroft3, Susan Hogue4, Zinaria Williams Liu5, Robert Seibert5.   

Abstract

PURPOSE: To examine the time burden of managing neovascular age-related macular degeneration (AMD) imposed on physicians, staff, patients, and caregivers.
DESIGN: Mixed-methods, prospective, observational time-and-motion study.
METHODS: The multicenter study was conducted from March 2011 through August 2012. Retina specialists administering ≥50 vascular endothelial growth factor (VEGF)-inhibitor injections monthly were surveyed and completed records for ≥5 patients scheduled for office visits within 3 weeks for anti-VEGF injection or monitoring. A survey was administered to 75 neovascular AMD patients aged ≥50 years who received ≥1 anti-VEGF injection in the past 6 months. Telephone interviews were conducted with 13 neovascular AMD patient caregivers.
RESULTS: Fifty-six physicians provided data for 221 patients with neovascular AMD. Patients accounted for 20% of the health care staff's time per week, with an average of 23 staff members. An average patient visit for neovascular AMD was 90 minutes (range: 13 minutes to >4 hours). Patients reported an average time per visit of almost 12 hours, including preappointment preparation (16 minutes), travel (66 minutes), waiting time (37 minutes), treatment time (43 minutes), and postappointment recovery (9 hours). Patients stated that caregivers took time away from work (22%) and personal activities (28%) to provide transportation to appointments.
CONCLUSIONS: Neovascular AMD management imposes a substantial time burden on physicians, staff, patients, and caregivers. There may be a need for additional support and/or reimbursement for services required by patients and caregivers and provided by physicians.
Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26142721     DOI: 10.1016/j.ajo.2015.06.023

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  35 in total

1.  Modifiable Determinants of Satisfaction with Intravitreal Treatment in Patients with Neovascular Age-Related Macular Degeneration.

Authors:  Paola S Calles-Monar; María R Sanabria; Ana M Alonso-Tarancon; Rosa M Coco-Martin; Agustín Mayo-Iscar
Journal:  Drugs Aging       Date:  2022-04-29       Impact factor: 3.923

2.  The Port Delivery System with ranibizumab: a new paradigm for long-acting retinal drug delivery.

Authors:  Shrirang V Ranade; Mark R Wieland; Tammy Tam; Jennifer C Rea; Judit Horvath; Aaron R Hieb; Weitao Jia; Lori Grace; Giulio Barteselli; Jay M Stewart
Journal:  Drug Deliv       Date:  2022-12       Impact factor: 6.819

3.  Sub-Tenon's capsule triamcinolone acetonide injection to prevent brolucizumab-associated intraocular inflammation.

Authors:  Taiichi Hikichi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2022-03-02       Impact factor: 3.535

Review 4.  [Atrophy of the macula in the context of its wet, age-related degeneration : An inescapable consequence of anti-VEGF therapy?]

Authors:  J G Garweg
Journal:  Ophthalmologe       Date:  2016-12       Impact factor: 1.059

5.  Sustained delivery of acriflavine from the suprachoroidal space provides long term suppression of choroidal neovascularization.

Authors:  Sean F Hackett; Jie Fu; Yoo Chun Kim; Hiroki Tsujinaka; Jikui Shen; Raquel Lima E Silva; Mahmood Khan; Zibran Hafiz; Tao Wang; Matthew Shin; Nicole M Anders; Ping He; Laura M Ensign; Justin Hanes; Peter A Campochiaro
Journal:  Biomaterials       Date:  2020-03-04       Impact factor: 12.479

6.  Physician, patient, and caregiver experience of different wet age-related macular degeneration anti-VEGF treatment regimens in Japan: a qualitative assessment.

Authors:  Tomohiro Iida; Keirei Ishii
Journal:  Clin Ophthalmol       Date:  2016-12-15

7.  The impact of different anti-vascular endothelial growth factor treatment regimens on reducing burden for caregivers and patients with wet age-related macular degeneration in a single-center real-world Japanese setting.

Authors:  Tsukasa Hanemoto; Yusuke Hikichi; Norimasa Kikuchi; Tadahiko Kozawa
Journal:  PLoS One       Date:  2017-12-08       Impact factor: 3.240

Review 8.  Progress of stem/progenitor cell-based therapy for retinal degeneration.

Authors:  Zhimin Tang; Yi Zhang; Yuyao Wang; Dandan Zhang; Bingqiao Shen; Min Luo; Ping Gu
Journal:  J Transl Med       Date:  2017-05-10       Impact factor: 5.531

9.  Comparison of Two Different Intravitreal Injection Techniques.

Authors:  Harvey S Uy; Jose Carlo M Artiaga
Journal:  Clin Ophthalmol       Date:  2021-06-08

10.  Delivery of Community-Based Palliative Care: Findings from a Time and Motion Study.

Authors:  Nrupen A Bhavsar; Kate Bloom; Jonathan Nicolla; Callie Gable; Abby Goodman; Andrew Olson; Matthew Harker; Janet Bull; Donald H Taylor
Journal:  J Palliat Med       Date:  2017-05-31       Impact factor: 2.947

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