Literature DB >> 35468115

Life threat during assaultive trauma: Critical posttraumatic stress disorder risk factors for injured patients.

Sydney C Timmer-Murillo1, Andrew Schramm, Terri A deRoon-Cassini.   

Abstract

BACKGROUND: Rates of posttraumatic stress disorder (PTSD) among injury survivors are higher relative to the general population, supporting the need to identify those most at risk for PTSD following injury given negative impact of PTSD on recovery. Perceived life threat and assaultive trauma are consistent risk factors for subsequent PTSD development, although less work has explored them in combination. The current study evaluated whether trauma type (assaultive vs. nonassaultive) and perceived life threat, together, led to greater PTSD symptoms 1 month and 6 months postinjury.
METHODS: Participants included adult injured trauma survivors admitted to a level 1 trauma center. While hospitalized, perceived life threat during trauma was assessed and mechanism of injury was collected via record review and was collapsed into two categories: assaultive and nonassaultive. The Clinician-Administered PTSD Scale (Diagnostic and Statistical Manual of Mental Disorders [Fifth Edition]) was administered at 1 month (N = 137) and 6 months (N = 220) after injury.
RESULTS: The four symptoms clusters of PTSD (intrusions, avoidance, hyperarousal, and negative mood/cognitions) were examined using four 2 (time) × 2 (life threat) × 2 (trauma type) mixed methods analyses of variance to assess differences based on risk factors and time. Results showed significant interaction effects of life threat, trauma type, and time for intrusive symptoms and avoidance symptoms. Individuals with life threat during assaultive traumas maintained heightened intrusive symptoms across time and increased avoidance at 6 months. On the other hand, participants with either life threat or assaultive traumas had decreased symptoms at 6 months.
CONCLUSION: Experiencing assaultive trauma and life threat led to greater symptoms of PTSD. Individuals with assaultive traumas who experienced life threat may represent a specific at-risk group following injury. Avoidance can protract functional impairment and impede access to care, negatively impacting recovery. This study highlights a need to assess for these peritrauma factors during hospitalization and supports early intervention targeting avoidance and intrusive symptoms in this group. LEVEL OF EVIDENCE: Prognostic/Epidemiologic, Level IV.
Copyright © 2022 American Association for the Surgery of Trauma.

Entities:  

Mesh:

Year:  2022        PMID: 35468115      PMCID: PMC9181289          DOI: 10.1097/TA.0000000000003543

Source DB:  PubMed          Journal:  J Trauma Acute Care Surg        ISSN: 2163-0755            Impact factor:   3.697


  28 in total

1.  Prevalence and treatment of depression and posttraumatic stress disorder among trauma patients with non-neurological injuries.

Authors:  Teresa M Bell; Ashley N Vetor; Ben L Zarzaur
Journal:  J Trauma Acute Care Surg       Date:  2018-11       Impact factor: 3.313

2.  Neural Substrates of Overgeneralized Conditioned Fear in PTSD.

Authors:  Antonia N Kaczkurkin; Philip C Burton; Shai M Chazin; Adrienne B Manbeck; Tori Espensen-Sturges; Samuel E Cooper; Scott R Sponheim; Shmuel Lissek
Journal:  Am J Psychiatry       Date:  2016-10-31       Impact factor: 18.112

3.  Posttraumatic stress disorder in injured adults: etiology by path analysis.

Authors:  A J Michaels; C E Michaels; M A Zimmerman; J S Smith; C H Moon; C Peterson
Journal:  J Trauma       Date:  1999-11

4.  Two years after injury: prevalence and early post-injury predictors of ongoing injury-related problems.

Authors:  Suzanne J Wilson; Gabrielle Davie; Sarah Derrett
Journal:  Qual Life Res       Date:  2017-02-22       Impact factor: 4.147

5.  Injury severity and quality of life: whose perspective is important?

Authors:  Karen J Brasel; Terri Deroon-Cassini; Ciarán T Bradley
Journal:  J Trauma       Date:  2010-02

6.  Utility of the injured trauma survivor screen to predict PTSD and depression during hospital admission.

Authors:  Joshua C Hunt; Marty Sapp; Cindy Walker; Ann Marie Warren; Karen Brasel; Terri A deRoon-Cassini
Journal:  J Trauma Acute Care Surg       Date:  2017-01       Impact factor: 3.313

Review 7.  Neural, psychophysiological, and behavioral markers of fear processing in PTSD: a review of the literature.

Authors:  Erel Shvil; Heather L Rusch; Gregory M Sullivan; Yuval Neria
Journal:  Curr Psychiatry Rep       Date:  2013-05       Impact factor: 5.285

8.  Neurobiological correlates of distinct post-traumatic stress disorder symptom profiles during threat anticipation in combat veterans.

Authors:  D W Grupe; J Wielgosz; R J Davidson; J B Nitschke
Journal:  Psychol Med       Date:  2016-03-16       Impact factor: 7.723

9.  Association Between Perceived Threat and the Development of Posttraumatic Stress Disorder Symptoms in Patients With Life-threatening Medical Emergencies.

Authors:  Jeena Moss; Michael B Roberts; Lisa Shea; Christopher W Jones; Hope Kilgannon; Donald E Edmondson; Stephen Trzeciak; Brian W Roberts
Journal:  Acad Emerg Med       Date:  2019-11-24       Impact factor: 3.451

10.  Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort.

Authors:  Terri A deRoon-Cassini; Carisa L Bergner; Samantha A Chesney; Nicholas R Schumann; Tara Sander Lee; Karen J Brasel; Cecilia J Hillard
Journal:  Transl Psychiatry       Date:  2022-02-01       Impact factor: 7.989

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