Literature DB >> 3546599

Biopterin in Parkinson's disease.

A P Moore, P O Behan, W Jacobson, W L Armarego.   

Abstract

Tetrahydrobiopterin is an essential co-factor in the natural synthesis of dopamine. Oral tetrahydrobiopterin was given in small doses to four patients with early Parkinson's disease but had no discernible effect.

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Year:  1987        PMID: 3546599      PMCID: PMC1033255          DOI: 10.1136/jnnp.50.1.85

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  6 in total

1.  In vivo enhancement of tyrosine hydroxylation in rat striatum by tetrahydrobiopterin.

Authors:  R Kettler; G Bartholini; A Pletscher
Journal:  Nature       Date:  1974-05-31       Impact factor: 49.962

2.  Therapeutic efficacy of tetrahydrobiopterin in Parkinson's disease.

Authors:  H C Curtius; A Niederwieser; R Levine; H Müldner
Journal:  Adv Neurol       Date:  1984

3.  Tetrahydrobiopterin in striatum: localization in dopamine nerve terminals and role in catecholamine synthesis.

Authors:  R A Levine; L P Miller; W Lovenberg
Journal:  Science       Date:  1981-11-20       Impact factor: 47.728

4.  Catecholamine-related enzymes and the biopterin cofactor in Parkinson's disease and related extrapyramidal diseases.

Authors:  T Nagatsu; T Yamaguchi; M K Rahman; J Trocewicz; K Oka; Y Hirata; I Nagatsu; H Narabayashi; T Kondo; R Iizuka
Journal:  Adv Neurol       Date:  1984

5.  Atypical phenylketonuria with defective biopterin metabolism. Monotherapy with tetrahydrobiopterin or sepiapterin, screening and study of biosynthesis in man.

Authors:  A Niederwieser; H C Curtius; M Wang; D Leupold
Journal:  Eur J Pediatr       Date:  1982-03       Impact factor: 3.183

6.  [Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system].

Authors:  H EHRINGER; O HORNYKIEWICZ
Journal:  Klin Wochenschr       Date:  1960-12-15
  6 in total
  1 in total

Review 1.  Is NADH effective in the treatment of Parkinson's disease?

Authors:  R H Swerdlow
Journal:  Drugs Aging       Date:  1998-10       Impact factor: 3.923

  1 in total

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