Literature DB >> 35463193

Leveraging Deep Representations of Radiology Reports in Survival Analysis for Predicting Heart Failure Patient Mortality.

Hyun Gi Lee1, Evan Sholle2, Ashley Beecy3, Subhi Al'Aref4, Yifan Peng1.   

Abstract

Utilizing clinical texts in survival analysis is difficult because they are largely unstructured. Current automatic extraction models fail to capture textual information comprehensively since their labels are limited in scope. Furthermore, they typically require a large amount of data and high-quality expert annotations for training. In this work, we present a novel method of using BERT-based hidden layer representations of clinical texts as covariates for proportional hazards models to predict patient survival outcomes. We show that hidden layers yield notably more accurate predictions than predefined features, outperforming the previous baseline model by 5.7% on average across C-index and time-dependent AUC. We make our work publicly available at https://github.com/bionlplab/heart_failure_mortality.

Entities:  

Year:  2021        PMID: 35463193      PMCID: PMC9034454          DOI: 10.18653/v1/2021.naacl-main.358

Source DB:  PubMed          Journal:  Proc Conf


  13 in total

1.  A simple algorithm for identifying negated findings and diseases in discharge summaries.

Authors:  W W Chapman; W Bridewell; P Hanbury; G F Cooper; B G Buchanan
Journal:  J Biomed Inform       Date:  2001-10       Impact factor: 6.317

2.  Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation.

Authors:  Michael J Pencina; Ralph B D'Agostino
Journal:  Stat Med       Date:  2004-07-15       Impact factor: 2.373

3.  Survival model predictive accuracy and ROC curves.

Authors:  Patrick J Heagerty; Yingye Zheng
Journal:  Biometrics       Date:  2005-03       Impact factor: 2.571

4.  On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data.

Authors:  Hajime Uno; Tianxi Cai; Michael J Pencina; Ralph B D'Agostino; L J Wei
Journal:  Stat Med       Date:  2011-01-13       Impact factor: 2.373

5.  Evaluating the yield of medical tests.

Authors:  F E Harrell; R M Califf; D B Pryor; K L Lee; R A Rosati
Journal:  JAMA       Date:  1982-05-14       Impact factor: 56.272

6.  A Deep Learning-Based Radiomics Model for Prediction of Survival in Glioblastoma Multiforme.

Authors:  Jiangwei Lao; Yinsheng Chen; Zhi-Cheng Li; Qihua Li; Ji Zhang; Jing Liu; Guangtao Zhai
Journal:  Sci Rep       Date:  2017-09-04       Impact factor: 4.379

7.  Time-dependent ROC curve analysis in medical research: current methods and applications.

Authors:  Adina Najwa Kamarudin; Trevor Cox; Ruwanthi Kolamunnage-Dona
Journal:  BMC Med Res Methodol       Date:  2017-04-07       Impact factor: 4.615

8.  DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network.

Authors:  Jared L Katzman; Uri Shaham; Alexander Cloninger; Jonathan Bates; Tingting Jiang; Yuval Kluger
Journal:  BMC Med Res Methodol       Date:  2018-02-26       Impact factor: 4.615

9.  Extraction of radiographic findings from unstructured thoracoabdominal computed tomography reports using convolutional neural network based natural language processing.

Authors:  Mohit Pandey; Zhuoran Xu; Evan Sholle; Gabriel Maliakal; Gurpreet Singh; Zahra Fatima; Daria Larine; Benjamin C Lee; Jing Wang; Alexander R van Rosendael; Lohendran Baskaran; Leslee J Shaw; James K Min; Subhi J Al'Aref
Journal:  PLoS One       Date:  2020-07-30       Impact factor: 3.240

10.  BioBERT: a pre-trained biomedical language representation model for biomedical text mining.

Authors:  Jinhyuk Lee; Wonjin Yoon; Sungdong Kim; Donghyeon Kim; Sunkyu Kim; Chan Ho So; Jaewoo Kang
Journal:  Bioinformatics       Date:  2020-02-15       Impact factor: 6.937

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  1 in total

1.  Quality Management of Pulmonary Nodule Radiology Reports Based on Natural Language Processing.

Authors:  Xiaolu Fei; Pengyu Chen; Lan Wei; Yue Huang; Yi Xin; Jia Li
Journal:  Bioengineering (Basel)       Date:  2022-06-01
  1 in total

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