| Literature DB >> 35455296 |
Flavius Cristian Mărcău1, Cătălin Peptan1, Ramona Mihaela Nedelcuță2, Vlad Dumitru Băleanu3, Anca Roxana Băleanu4, Bogdan Niculescu3.
Abstract
PURPOSE: Once vaccination against COVID-19 was also possible for children over 12 years of age, parents/legal guardians had to give their consent for their vaccination. It is a crucial moment, given the large number of infected people in Romania and the fact that these children are a source of transmission of the virus in the community. The refusal or hesitation of the parents/legal guardians, regarding the agreement for the vaccination of the children, determined us to focus on this subject, wishing, based on the questioning of as many parents as possible, to extract the reasons underlying these decisions.Entities:
Keywords: Romania; anti-COVID-19 vaccine; children vaccination; hesitation
Year: 2022 PMID: 35455296 PMCID: PMC9024740 DOI: 10.3390/vaccines10040547
Source DB: PubMed Journal: Vaccines (Basel) ISSN: 2076-393X
Required dates and research questions.
| Required Dates | Questions |
|---|---|
| Vaccination of children with vaccines included in the national vaccination schedule in Romania | Does the high uptake of vaccination with vaccines included in Romania’s national schedule and optional vaccines increase the acceptability of vaccination with a COVID-19 vaccine? |
| Vaccination of children with optional vaccines recommended for children (hepatitis B vaccine, hexavalent vaccine, tuberculosis vaccine, etc.) | |
| COVID-19 vaccination of parents | Does vaccination/non-vaccination of parents/legal guardians with an COVID-19 vaccine influence the vaccination decision of their children? |
| COVID-19 vaccination of children | |
| Parents’ trust in “fake news” claims | Does a high reliance on “fake news” lead to the rejection/refusal to vaccinate children with a COVID-19 vaccine? |
Representation of socio-demographic data of participants.
| Age | Sex | Environment of Residence | Educational Level | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Female | Male | Do Not Answear | Urban | Rural | Secondary Education | High School | Faculty | Masters | Phd | |
| 21–25 | 9 | 3 | - | 10 | 2 | 1 | 5 | 3 | 3 | - |
| 26–30 | 33 | 5 | - | 26 | 12 | 1 | 6 | 12 | 16 | 3 |
| 31–35 | 80 | 13 | 1 | 72 | 22 | - | 26 | 34 | 30 | 4 |
| 36–40 | 119 | 16 | 1 | 101 | 35 | 2 | 14 | 66 | 46 | 8 |
| 41–45 | 133 | 16 | 2 | 125 | 26 | 3 | 19 | 85 | 39 | 5 |
| 46–50 | 76 | 15 | - | 76 | 15 | 2 | 13 | 41 | 29 | 6 |
| 51–55 | 33 | 7 | 1 | 32 | 9 | - | 9 | 20 | 9 | 3 |
| 56–60 | 8 | 2 | - | 8 | 2 | - | 3 | 5 | 1 | 1 |
| 61–65 | 2 | - | - | 2 | - | - | 1 | 1 | - | |
| 66+ | 5 | 1 | - | 5 | 1 | - | 4 | 2 | - | - |
Infections with COVID-19 disease of respondents and their children.
| Age Range for Parents/Legal Guardians | Parent/Legal Guardian Who Had COVID-19 Disease | Children Who Had COVID-19 | ||
|---|---|---|---|---|
| % | % | |||
| 21–25 | 50 | 16.6 | ||
| 26–30 | 23.6 | 18.4 | ||
| 31–35 | 38.3 | 25.5 | ||
| 36–40 | 25.7 | 16.9 | ||
| 41–45 | 33.7 | 28.8 | ||
| 46–50 | 34 | 26.7 | ||
| 51–55 | 26.8 | 29.2 | ||
| 56–60 | 20 | 30 | ||
| 61–65 | 100 | 100 | ||
| 66+ | 33.3 | 33.3 | ||
| Statistical analysis | Mean | 0.3854 | Mean | 0.3254 |
| Standard Error | 0.073407871 | Standard Error | 0.077210563 | |
| Median | 0.335 | Median | 0.2775 | |
| Standard Deviation | 0.232136071 | Standard Deviation | 0.24416124 | |
| Sample Variance | 0.053887156 | Sample Variance | 0.059614711 | |
| Kurtosis | 6.560056789 | Kurtosis | 8.482739794 | |
| Skewness | 2.441174735 | Skewness | 2.821020663 | |
| Confidence Level (95.0%) | 0.166060142 | Confidence Level (95.0%) | 0.174662429 | |
Vaccination of adults and children with the mandatory vaccines included in the national scheme.
| Age Range for Parents/Legal Guardians | Parents Vaccinated with Vaccines Included in the National Vaccination Schedule | Children Vaccinated with Vaccines Included in the National Vaccination Schedule | ||
|---|---|---|---|---|
| % | % | |||
| 21–25 | 100 | 83.3 | ||
| 26–30 | 94.7 | 92.1 | ||
| 31–35 | 98.9 | 97.8 | ||
| 36–40 | 97 | 95.5 | ||
| 41–45 | 100 | 99.3 | ||
| 46–50 | 98.9 | 98.9 | ||
| 51–55 | 97.5 | 97.5 | ||
| 56–60 | 100 | 100 | ||
| 61–65 | 100 | 100 | ||
| 66+ | 100 | 100 | ||
| Statistical analysis | Mean | 0.987 | Mean | 0.9644 |
| Standard Error | 0.005663 | Standard Error | 0.016587 | |
| Median | 0.9945 | Median | 0.9835 | |
| Standard Deviation | 0.017907 | Standard Deviation | 0.052451 | |
| Sample Variance | 0.000321 | Sample Variance | 0.002751 | |
| Kurtosis | 1.618865 | Kurtosis | 4.529729 | |
| Skewness | −1.44253 | Skewness | −2.09243 | |
| Confidence Level (95.0%) | 0.01281 | Confidence Level (95.0%) | 0.037522 | |
Confidence in the mandatory vaccines included in the national scheme and in the optional vaccines (like rotavirus vaccine, anti hepatitis A and B, meningococcal vaccine, etc.).
| Age Range for Parents/Legal Guardians | Degree of Confidence in Vaccines Included in the National Vaccination Schedule and in Optional Vaccines (Hepatitis B Vaccine, Hexavalent Vaccine, Tuberculosis Vaccine, etc.). | |||
|---|---|---|---|---|
| Vaccines Included in the National Scheme | Optional Vaccines | |||
| % | % | |||
| 21–25 | 83.3 | 83.3 | ||
| 26–30 | 81.5 | 71 | ||
| 31–35 | 91.4 | 72.3 | ||
| 36–40 | 95.5 | 83 | ||
| 41–45 | 96.6 | 81.4 | ||
| 46–50 | 93.4 | 76.9 | ||
| 51–55 | 87.8 | 65.8 | ||
| 56–60 | 90 | 90 | ||
| 61–65 | 50 | 100 | ||
| 66+ | 100 | 83.3 | ||
| Statistical analysis | Mean | 0.8695 | Mean | 0.807 |
| Standard Error | 0.044923 | Standard Error | 0.031258 | |
| Median | 0.907 | Median | 0.822 | |
| Standard Deviation | 0.14206 | Standard Deviation | 0.098848 | |
| Sample Variance | 0.020181 | Sample Variance | 0.009771 | |
| Kurtosis | 5.898115 | Kurtosis | 0.454139 | |
| Skewness | −2.25403 | Skewness | 0.456268 | |
| Confidence Level (95.0%) | 0.101623 | Confidence Level (95.0%) | 0.070711 | |
Schedule of anti-COVID-19 vaccination of parents and their children.
| Age Range for Parents/Legal Guardians | Vaccination of Parents/Legal Guardians and Children against COVID-19 | |||
|---|---|---|---|---|
| Parents/Guardians | Children | |||
| % | % | |||
| 21–25 | 41.6 | 16.6 | ||
| 26–30 | 55.2 | 2.6 | ||
| 31–35 | 64.8 | 6.3 | ||
| 36–40 | 79.4 | 21.3 | ||
| 41–45 | 73.5 | 40.4 | ||
| 46–50 | 73.6 | 58.2 | ||
| 51–55 | 58.5 | 51.2 | ||
| 56–60 | 80 | 70 | ||
| 61–65 | 50 | 50 | ||
| 66+ | 83.3 | 66.6 | ||
| Statistical analysis | Mean | 0.6599 | Mean | 0.3832 |
| Standard Error | 0.044901732 | Standard Error | 0.078654491 | |
| Median | 0.6915 | Median | 0.452 | |
| Standard Deviation | 0.141991745 | Standard Deviation | 0.248727338 | |
| Sample Variance | 0.020161656 | Sample Variance | 0.061865289 | |
| Kurtosis | −1.100961288 | Kurtosis | −1.582192121 | |
| Skewness | −0.439693194 | Skewness | −0.248886703 | |
| Confidence Level (95.0%) | 0.101574775 | Confidence Level (95.0%) | 0.177928819 | |
Parents agree to vaccinate their children when they reach the recommended minimum age or when vaccines will be available for their age.
| Age Range for Parents/Legal Guardians | Agreement of Parents/Legal Guardians to Vaccinate Children against COVID-19 When They Reach the Minimum Age for Vaccination or When a Vaccine Will Be Available for Their Age | |
|---|---|---|
| % | ||
| 21–25 | 33.3 | |
| 26–30 | 39.4 | |
| 31–35 | 44.6 | |
| 36–40 | 58.8 | |
| 41–45 | 58.9 | |
| 46–50 | 64.8 | |
| 51–55 | 58.5 | |
| 56–60 | 80 | |
| 61–65 | 100 | |
| 66+ | 83.3 | |
| Statistical analysis | Mean | 0.6216 |
| Standard Error | 0.065816107 | |
| Median | 0.5885 | |
| Standard Deviation | 0.208128806 | |
| Sample Variance | 0.0433176 | |
| Kurtosis | −0.37428505 | |
| Skewness | 0.430758375 | |
| Confidence Level (95.0%) | 0.148886379 | |
The level of readiness of parents vaccinated against COVID-19 to vaccinate their own children.
| Age Range for Parents/Legal Guardians | Vaccinating Children against COVID-19—Vaccinated Parents against COVID-19. | |
|---|---|---|
| % | ||
| 21–25 | 15 | |
| 26–30 | 4.7 | |
| 31–35 | 9.8 | |
| 36–40 | 26.8 | |
| 41–45 | 52.2 | |
| 46–50 | 77.6 | |
| 51–55 | 83.3 | |
| 56–60 | 87.5 | |
| 61–65 | 100 | |
| 66+ | 80 | |
| Statistical analysis | Mean | 0.04379562 |
| Standard Error | 0.016573612 | |
| Median | 0.015815085 | |
| Standard Deviation | 0.052410363 | |
| Sample Variance | 0.002746846 | |
| Kurtosis | −0.063979027 | |
| Skewness | 1.180022504 | |
| Confidence Level (95.0%) | 0.037492115 | |
Readiness of unvaccinated parents against COVID-19 for vaccination of children.
| Age Range for Parents/Legal Guardians | Vaccinating Children against COVID-19—Unvaccinated Parents against COVID-19 | |
|---|---|---|
| % | ||
| 21–25 | 0% | |
| 26–30 | 0% | |
| 31–35 | 0% | |
| 36–40 | 0% | |
| 41–45 | 7.5% | |
| 46–50 | 4.17% | |
| 51–55 | 5.8% | |
| 56–60 | 0% | |
| 61–65 | 0% | |
| 66+ | 0% | |
| Statistical analysis | Mean | 0.002941176 |
| Standard Error | 0.001807754 | |
| Median | 0 | |
| Standard Deviation | 0.00571662 | |
| Sample Variance | 3.26797E-05 | |
| Kurtosis | 5.356401384 | |
| Skewness | 2.269834215 | |
| Confidence Level (95.0%) | 0.004089423 | |
Identifying the degree of trust given to “fake news” statements [14].
| Fake News Allegations | Disagree | Uncertain | Agree | P | |||
|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | ||
| There is a global secret society who wants to control the world | 370 | 63.8 | 80 | 13.7 | 131 | 22.5 | P = 0.02 |
| COVID-19 vaccines are made to reduce the population of the Earth (infertility, death etc.) | 420 | 72.2 | 66 | 11.3 | 95 | 16.3 | P > 0.01 |
| Doctors are paid to inoculate children with a vaccine that would help reduce the Earth’s population | 441 | 75.8 | 68 | 11.7 | 72 | 12.3 | P > 0.01 |
| Children who get the COVID-19 vaccine will die in the next few years from inoculated substances | 435 | 74.8 | 101 | 17.3 | 45 | 7.7 | P > 0.01 |
| Children who get the COVID-19 vaccine will become infertile due to inoculated substances | 441 | 75.9 | 94 | 16.1 | 46 | 7.9 | P > 0.01 |
| Vaccination is intended to reduce the number of elderly people | 438 | 75.5 | 57 | 9.8 | 85 | 14.6 | P > 0.01 |
| Vaccination on a global scale aims to enrich vaccine manufacturers | 335 | 57.6 | 71 | 12.2 | 175 | 30.1 | P = 0.03 |
| There is a global secret society that wants to reduce the population of the Earth | 405 | 68.7 | 58 | 9.9 | 118 | 20.3 | P > 0.01 |
| New vaccines based on messenger RNA produce dangerous genetic changes | 382 | 65.7 | 98 | 16.8 | 101 | 17.3 | P < 0.05 |
Figure 1Correlation between parents/legal guardians and children vaccinated/not vaccinated against COVID-19. **. Correlation is significant at the 0.01 level (2-tailed).
Figure 2Graphic representation of the correlation between the acceptance of parents/legal guardians of vaccines included in the national vaccination schedule, optional vaccines, and the COVID-19 vaccine. **. Correlation is significant at the 0.01 level (2-tailed).
Figure 3Graphic representation of the correlation between individuals who trust “fake news” (grading 4 and 5) and their decision to vaccinate their children. **. Correlation is significant at the 0.01 level (2-tailed).