| Literature DB >> 35455294 |
Robbert J Langwerden1,2, Eric F Wagner1,2,3, Michelle M Hospital1,2,4, Staci L Morris1,2,3, Victor Cueto5, Olveen Carrasquillo5, Sara C Charles1,2, Katherine R Perez1,2, María Eugenia Contreras-Pérez1,2, Adriana L Campa2,6.
Abstract
By the spring of 2021, most of the adult U.S. population became eligible to receive a COVID-19 vaccine. Yet, by the summer of 2021, the vaccination rate stagnated. Given the immense impact COVID-19 has had on society and individuals, and the surge of new variant strains of the virus, it remains urgent to better understand barriers to vaccination, including the impact of variations in trusted sources of COVID-19 information. The goal of the present study was to conduct a cross-sectional, community-engaged, and person-centered study of trusted sources of COVID-19 information using latent profile analysis (LPA). The aims were to (1) identify the number and nature of profiles of trusted sources of COVID-19 information, and (2) determine whether the trust profiles were predictive of COVID-19 vaccination attitudes and various demographic categories. Participants included mostly racial and ethnic minority individuals (82.4%) recruited by various community-based agencies in South Florida. The LPA evidenced an optimal 3-class solution characterized by low (n = 80)-, medium (n = 147)-, and high (n = 52)-trust profiles, with high trust statistically significantly predictive of vaccination willingness. The profiles identified could be important targets for public health dissemination efforts to reduce vaccine hesitancy and increase COVID-19 vaccination uptake. The general level of trust in COVID-19 information sources was found to be an important factor in predicting COVID-19 vaccination willingness.Entities:
Keywords: COVID-19; information sources; latent class analysis; trust; vaccine hesitancy; vaccines
Year: 2022 PMID: 35455294 PMCID: PMC9031496 DOI: 10.3390/vaccines10040545
Source DB: PubMed Journal: Vaccines (Basel) ISSN: 2076-393X
Demographic Characteristics of Survey Respondents: overall, by source, and compared to census rates.
| Characteristic | Site 1 | Site 2 | Combined | Miami–Dade County |
|---|---|---|---|---|
| ( | ( | ( | Census 1 | |
| Vaccinated * 2 | 110 (72.4%) | 76 (59.8%) | 186 (66.7%) | 79% |
| Not vaccinated | 42 (27.6%) | 51 (40.2%) | 93 (33.3%) | 21% |
| Age | ||||
| 18–82 | 18–80 | 18–82 | ||
| Gender | ||||
| Female | 103 (68.2%) | 89 (70.6%) | 192 (69.3%) | 51.42% |
| Male | 47 (31.1%) | 36 (28.6%) | 83 (30%) | 48.58% |
| Nonbinary, genderqueer, or genderfluid | 1 (0.7%) | 1 (0.8%) | 2 (0.7%) | |
| Race | ||||
| White | 104 (68.4%) | 77 (60.6%) | 181 (64.9%) | 75.8% |
| Black or African American * | 30 (19.7%) | 40 (31.5%) | 70 (25.1%) | 16.42% |
| Asian | 8 (5.3%) | 3 (2.4%) | 11 (3.9%) | 1.53% |
| American Indian or Alaska Native | 2 (1.3%) | 1 (0.8%) | 3 (1.1%) | 0.21% |
| Native Hawaiian or Other Pacific Islander | 1 (0.7%) | 0 (0%) | 1 (0.4%) | 0.02% |
| Prefer not to answer | 7 (4.6%) | 8 (6.3%) | 15 (5.4%) | |
| Ethnicity | ||||
| Hispanic or Latino | 102 (68%) | 71 (57.7%) | 173 (63.4%) | 71.51% |
| Race & Ethnicity | ||||
| Hispanic or Latino & Black or African American | 8 (5.3%) | 2 (1.6%) | 10 (3.7%) | |
| Hispanic or Latino & American Indian or Alaska Native | 2 (1.3%) | 1 (0.8%) | 3 (1.1%) | |
| Hispanic or Latino & Native Hawaiian or Pacific Islander | 1 (0.7%) | 0 (0%) | 1 (0.4%) | |
| Sexual Orientation | ||||
| Bisexual | 7 (4.8%) | 1 (0.8%) | 8 (3%) | |
| Gay | 7 (4.8%) | 2 (1.6%) | 9 (3.3%) | |
| Lesbian | 2 (1.4%) | 1 (0.8%) | 3 (1.1%) | |
| Straight | 127 (87.6%) | 120 (95.2%) | 247 (91.1%) | |
| Other | 2 (1.4%) | 2 (1.6%) | 4 (1.5%) | |
| Born in the U.S. | ||||
| Yes | 83 (57.6%) | 70 (57.4%) | 153 (57.5%) | 45.4% |
| English as first language | ||||
| No | 47 (31.3%) | 35 (28.5%) | 82 (30%) | 77% |
| Educational level | ||||
| Less than high school | 0 (0%) | 1 (0.8%) | 1 (0.4%) | 9.39% |
| Some high school | 2 (1.3%) | 3 (2.4%) | 5 (1.8%) | 8.43% |
| High school graduate or GED | 32 (21.3%) | 27 (21.6%) | 59 (21.5%) | 27.31% |
| Associates or technical degree | 28 (18.7%) | 21 (16.8%) | 49 (17.8%) | 9.40% |
| Bachelor’s degree | 54 (36%) | 45 (36%) | 99 (36%) | 19.32% |
| Graduate degree | 34 (22.7%) | 28 (22.4%) | 62 (22.5%) | 8.29% |
| Employment status | ||||
| Working for pay—part time | 34 (22.4%) | 25 (19.7%) | 59 (21.1%) | |
| Working for pay—full time * | 72 (47.4%) | 75 (59.1%) | 147 (52.7%) | |
| Working without pay * | 4 (2.6%) | 0 (0%) | 4 (1.4%) | |
| On leave | 0 (0%) | 1 (0.8%) | 1 (0.4%) | |
| Unemployed and looking for a job | 12 (7.9%) | 7 (5.5%) | 19 (6.8%) | |
| Unemployed and not looking for a job | 2 (1.3%) | 3 (2.4%) | 5 (1.8%) | |
| Retired | 5 (3.3%) | 4 (3.1%) | 9 (3.2%) | |
| Staying at home, taking care of the home or others | 8 (5.3%) | 7 (5.5%) | 15 (5.4%) | |
| Not able to work because of disability | 1 (0.7%) | 0 (0%) | 1 (0.4%) | |
| Going to school | 23 (15.1%) | 16 (12.6%) | 39 (14%) | |
| Other | 4 (2.6%) | 2 (1.6%) | 6 (2.2%) |
Note: Percentages reflect valid percentages. 1 Census data was retrieved from the Miami–Dade County tracker [33]. 2 Vaccination data were retrieved from [34]. * Statistically significant difference.
Figure 1Visual display of LPA results of the 3-class solution of 11 trusted sources of information. Note: Profile 1 (n = 80), Profile 2 (n = 147), Profile 3 (n = 52).
Figure 2Vaccination willingness scores as proportions (%) by trust profile. Note: All percentages use the profile group’s size as denominator; Profile 1 (n = 80), Profile 2 (n = 147), Profile 3 (n = 52).
Test results of profile membership by demographic outcome.
| Covariate | Value |
| Effect Size |
|---|---|---|---|
| Site | 12.39 |
| 0.2 |
| Age | 1.67 | 0.2 | 0.006 |
| U.S. Born | 0.82 | 0.67 | 0.06 |
| Gender | 16.54 |
| 0.17 |
| Sexual Orientation | 13.51 | 0.1 | 0.16 |
| Hispanic/Latino | 5.32 | 0.07 | 0.14 |
| White | 0.533 | 0.77 | 0.04 |
| Black or African American | 0.68 | 0.71 | 0.05 |
| Asian | 3.94 | 0.14 | 0.12 |
| American Indian or Alaska Native | 0.7 | 0.7 | 0.05 |
| Native Hawaiian or Pacific Islander | 2.5 | 0.29 | 0.1 |
| Educational level | 2.57 | 0.99 | 0.07 |
| Income | 8.89 | 0.84 | 0.14 |
| Full-time employment | 3.31 | 0.19 | 0.11 |
Note: All significant tests were conducted using Pearson Chi-square tests of independence, except for age, for which an ANOVA was conducted. Effect sizes represent Cramer’s V (0–0.3 weak, 0.4–0.5 medium, >0.5 strong) for the Chi-square tests and r-squared for the ANOVA. Bolded p-values are significant at the 0.05 level.