| Literature DB >> 33621500 |
Abstract
Herd immunity is an important yet often misunderstood concept in epidemiology. As immunity accumulates in a population - naturally during the course of an epidemic or through vaccination - the spread of an infectious disease is limited by the depletion of susceptible hosts. If a sufficient proportion of the population is immune - above the 'herd immunity threshold' - then transmission generally cannot be sustained. Maintaining herd immunity is therefore critical to long-term disease control. In this primer, we discuss the concept of herd immunity from first principles, clarify common misconceptions, and consider the implications for disease control.Entities:
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Year: 2021 PMID: 33621500 DOI: 10.1016/j.cub.2021.01.006
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834