Literature DB >> 354520

Dissociation between ion permeability and the lethal action of polyene antibiotics on Candida albicans.

W C Chen, D L Chou, D S Feingold.   

Abstract

Kinetic data on potassium release from and killing of Candida albicans by the four polyene antibiotics amphotericin B, amphotericin B methyl ester hydrochloride, nystatin, and nystatin methyl ester hydrochloride are presented. The nystatins were relatively more effective than the amphotericins in causing potassium release rather than killing. These data suggest that the aqueous channels or pores formed by the polyene antibiotics are not central to the lethal action of the drugs.

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Year:  1978        PMID： 354520      PMCID： PMC352362          DOI： 10.1128/AAC.13.6.914

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

Review 1.  Fungal sterols and the mode of action of the polyene antibiotics.

Authors:  J M Hamilton-Miller
Journal:  Adv Appl Microbiol       Date:  1974       Impact factor: 5.086

Review 2.  Aqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B.

Authors:  A Finkelstein; R Holz
Journal:  Membranes       Date:  1973

3.  Polyene macrolide derivatives. I. N-acylation and esterification reactions with amphotericin B.

Authors:  W Mechlinski; C P Schaffner
Journal:  J Antibiot (Tokyo)       Date:  1972-04       Impact factor: 2.649

Review 4.  Polyene antibiotic - sterol interaction.

Authors:  A W Norman; A M Spielvogel; R G Wong
Journal:  Adv Lipid Res       Date:  1976

5.  Interaction of the polyene antibiotics with lipid bilayer vesicles containing cholesterol.

Authors:  M P Gent; J H Prestegard
Journal:  Biochim Biophys Acta       Date:  1976-02-19

6.  Selective toxicity of the polyene antibiotics and their methyl ester derivatives.

Authors:  W C Chen; I J Sud; D L Chou; D S Feingold
Journal:  Biochem Biophys Res Commun       Date:  1977-01-24       Impact factor: 3.575

7.  The interaction of amphotericin B methyl ester with protoplasts of Candida albicans.

Authors:  D Kerridge; T Y Koh; A M Johnson
Journal:  J Gen Microbiol       Date:  1976-09

8.  Polyene antibiotic-sterol interactions in membranes of Acholesplasma laidlawii cells and lecithin liposomes. II. Temperature dependence of the polyene antibiotic-sterol complex formation.

Authors:  B de Kruijff; W J Gerritsen; A Oerlemans; P W van Dijck; R A Demel; L L van Deenen
Journal:  Biochim Biophys Acta       Date:  1974-02-26

9.  Polyene antibiotic-sterol interactions in membranes of Acholeplasma laidlawii cells and lecithin liposomes. 3. Molecular structure of the polyene antibiotic-cholesterol complexes.

Authors:  B de Kruijff; R A Demel
Journal:  Biochim Biophys Acta       Date:  1974-02-26

10.  Pores formed in lipid bilayer membranes by nystatin, Differences in its one-sided and two-sided action.

Authors:  A Marty; A Finkelstein
Journal:  J Gen Physiol       Date:  1975-04       Impact factor: 4.086
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  21 in total

1.  Evaluation of antifungal activity of antimycotics by automatic analyzing system.

Authors:  K Oh; H Matsuoka; O Sumita; K Takatori; H Kurata
Journal:  Mycopathologia       Date:  1992-05       Impact factor: 2.574

2.  Amphotericin primarily kills yeast by simply binding ergosterol.

Authors:  Kaitlyn C Gray; Daniel S Palacios; Ian Dailey; Matthew M Endo; Brice E Uno; Brandon C Wilcock; Martin D Burke
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-17       Impact factor: 11.205

3.  The production of reactive oxygen species is a universal action mechanism of Amphotericin B against pathogenic yeasts and contributes to the fungicidal effect of this drug.

Authors:  Ana Cecilia Mesa-Arango; Nuria Trevijano-Contador; Elvira Román; Ruth Sánchez-Fresneda; Celia Casas; Enrique Herrero; Juan Carlos Argüelles; Jesús Pla; Manuel Cuenca-Estrella; Oscar Zaragoza
Journal:  Antimicrob Agents Chemother       Date:  2014-08-25       Impact factor: 5.191

4.  A post-PKS oxidation of the amphotericin B skeleton predicted to be critical for channel formation is not required for potent antifungal activity.

Authors:  Daniel S Palacios; Thomas M Anderson; Martin D Burke
Journal:  J Am Chem Soc       Date:  2007-10-23       Impact factor: 15.419

5.  Identification of Off-Patent Drugs That Show Synergism with Amphotericin B or That Present Antifungal Action against Cryptococcus neoformans and Candida spp.

Authors:  Suélen Andreia Rossi; Haroldo Cesar de Oliveira; Daniel Agreda-Mellon; José Lucio; Maria José Soares Mendes-Giannini; Jesús Pablo García-Cambero; Oscar Zaragoza
Journal:  Antimicrob Agents Chemother       Date:  2020-03-24       Impact factor: 5.191

6.  Dose range evaluation of liposomal nystatin and comparisons with amphotericin B and amphotericin B lipid complex in temporarily neutropenic mice infected with an isolate of Aspergillus fumigatus with reduced susceptibility to amphotericin B.

Authors:  D W Denning; P Warn
Journal:  Antimicrob Agents Chemother       Date:  1999-11       Impact factor: 5.191

7.  The polyene macrolide antibiotics.

Authors:  D Kerridge
Journal:  Postgrad Med J       Date:  1979-09       Impact factor: 2.401

8.  Involvement of oxidative damage in erythrocyte lysis induced by amphotericin B.

Authors:  J Brajtburg; S Elberg; D R Schwartz; A Vertut-Croquin; D Schlessinger; G S Kobayashi; G Medoff
Journal:  Antimicrob Agents Chemother       Date:  1985-02       Impact factor: 5.191

9.  Enhanced action of amphotericin B on Leishmania mexicana resulting from heat transformation.

Authors:  H Ramos; J Milhaud; B E Cohen; J Bolard
Journal:  Antimicrob Agents Chemother       Date:  1990-08       Impact factor: 5.191

10.  Physicochemical cell damage in relation to lethal amphotericin B action.

Authors:  W H Beggs
Journal:  Antimicrob Agents Chemother       Date:  1994-02       Impact factor: 5.191
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