Ryo Asaoka1,2,3,4,5, Manabu Miyata6, Akio Oishi6,7, Yuri Fujino8,9,10, Hiroshi Murata9, Keiko Azuma9, Ryo Obata9, Tatsuya Inoue9,11. 1. Department of Ophthalmology, Seirei Hamamatsu General Hospital, Shizuoka, Japan. rasaoka-tky@umin.ac.jp. 2. Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. rasaoka-tky@umin.ac.jp. 3. Seirei Christopher University, Shizuoka, Japan. rasaoka-tky@umin.ac.jp. 4. Nanovision Research Division, Research Institute of Electronics, Shizuoka University, Shizuoka, Japan. rasaoka-tky@umin.ac.jp. 5. The Graduate School for the Creation of New Photonics Industries, Shizuoka, Japan. rasaoka-tky@umin.ac.jp. 6. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan. 7. Department of Ophthalmology and Visual Sciences, Nagasaki University, Nagasaki, Japan. 8. Department of Ophthalmology, Seirei Hamamatsu General Hospital, Shizuoka, Japan. 9. Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. 10. Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan. 11. Department of Ophthalmology and Micro-Technology, Yokohama City University, Kanagawa, Japan.
Abstract
BACKGROUND/ OBJECTIVES: To investigate the association between visual acuity (VA) and visual field (VF) and its reproducibility in patients with retinitis pigmentosa (RP). SUBJECTS/ METHODS: The study cohort comprised 227 eyes of 227 patients with RP. The reproducibility of two Humphrey VF tests (10-2 Swedish Interactive Threshold Algorithm [SITA] tests) performed within a period of 3 months was calculated using the root mean squared error (RMSE) of each VF test point's sensitivity. The association between the logarithm of the minimum angle of resolution (logMAR) VA and VF sensitivity was investigated. Additionally, the relationship between RMSE and age, fixation loss, false positives, false negatives, and logMAR VA was determined. RESULTS: The association between visual sensitivity and VA was most tight at the fovea, and it became weak toward the peripheral region in an eccentric manner. VF reproducibility appreciably increased as VA decreased. In particular, reproducibility was significantly decreased when logMAR VA was >0.5 compared with logMAR VA ≤ 0. CONCLUSION: Reproducibility of VF tests decreases with a decrease in VA. Careful consideration is necessary when a patient's logMAR VA is >0.5.
BACKGROUND/ OBJECTIVES: To investigate the association between visual acuity (VA) and visual field (VF) and its reproducibility in patients with retinitis pigmentosa (RP). SUBJECTS/ METHODS: The study cohort comprised 227 eyes of 227 patients with RP. The reproducibility of two Humphrey VF tests (10-2 Swedish Interactive Threshold Algorithm [SITA] tests) performed within a period of 3 months was calculated using the root mean squared error (RMSE) of each VF test point's sensitivity. The association between the logarithm of the minimum angle of resolution (logMAR) VA and VF sensitivity was investigated. Additionally, the relationship between RMSE and age, fixation loss, false positives, false negatives, and logMAR VA was determined. RESULTS: The association between visual sensitivity and VA was most tight at the fovea, and it became weak toward the peripheral region in an eccentric manner. VF reproducibility appreciably increased as VA decreased. In particular, reproducibility was significantly decreased when logMAR VA was >0.5 compared with logMAR VA ≤ 0. CONCLUSION: Reproducibility of VF tests decreases with a decrease in VA. Careful consideration is necessary when a patient's logMAR VA is >0.5.