Literature DB >> 35436818

Clinical-epidemiological Profile of Coronavirus Disease 19 Associated Mucomycosis (CAM) and Relation with Zinc and Iron Levels.

Ritu Karoli1, Manish Raj Kulshreshtha2, Nikhil Gupta3, Mridu Singh3, Vikram Singh4, Shobhit Shakya3.   

Abstract

INTRODUCTION: Coronavirus disease associated mucormycosis (CAM), perturbed a lot by reaching to epidemic proportions particularly during the second wave of the pandemic.
MATERIAL AND METHODS: This was a retrospective, observational study of patients with COVID-19-associated mucomycosis admitted in April-May 2021 at a tertiary care teaching hospital. Demographic profile, clinical and laboratory parameters were recorded Multidisciplinary treatment including antifungals and surgical interventions were noted.
RESULTS: This study included 98patients of mucormycosis, diagnosed on the basis of clinical and radiological findings and later were confirmed by microbiological investigations. Out of 98 patients, 72 had rhino orbital, 24 had rhino-orbitalcerebral and 2 had pulmonary mucormycosis. Twelve had coinfection of covid 19 while 86 had developed mucormycosis within 3 weeks.
CONCLUSION: CAM has posed as a continuum of challenges faced during the pandemic of covid 19. This rare and life threatening complication requires high index of suspicion for early diagnosis. Multidisciplinary involvement and timely interventions including antifungal pharmacotherapy, stringent glycemic control and surgical debridement can reduce the mortality. Mucormycosis is uniformly associated with low iron levels but role of zinc needs to be further studied. © Journal of the Association of Physicians of India 2011.

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Year:  2022        PMID: 35436818

Source DB:  PubMed          Journal:  J Assoc Physicians India        ISSN: 0004-5772


  1 in total

1.  Serum glucose-regulated protein 78 (GRP78) levels in COVID-19-associated mucormycosis: results of a case-control study.

Authors:  Valliappan Muthu; Manpreet Dhaliwal; Arunima Sharma; Divya Nair; H Mohan Kumar; Shivaprakash M Rudramurthy; Inderpaul Singh Sehgal; Hansraj Choudhary; Naresh Panda; Arunaloke Chakrabarti; Ritesh Agarwal
Journal:  Mycopathologia       Date:  2022-06-21       Impact factor: 3.785

  1 in total

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