Literature DB >> 35434270

CircZNF609 as a prototype to elucidate the biological function of circRNA-mRNA interactions.

Manuel Beltran1, Francesca Rossi1, Irene Bozzoni1,2.   

Abstract

Circular RNAs (circRNAs) are expressed and are regulated in many biological processes but little is known about their ability to directly control mRNA homeostasis. We show that circRNA zinc finger protein 609 (circZNF609) interacts with several mRNAs increasing the final protein levels, which in the case of the cytoskeleton-associated protein 5 (CKAP5) leads to a stabilized microtubule cytoskeleton and an enhanced tumor cell proliferation.
© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

Entities:  

Keywords:  CKAP5; Microtubules; RNA-RNA interaction; anti-cancer treatments; circRnas; rhabdomyosarcoma

Year:  2022        PMID： 35434270      PMCID： PMC9009943          DOI： 10.1080/23723556.2022.2055939

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  9 in total

1.  XMAP215 is a processive microtubule polymerase.

Authors:  Gary J Brouhard; Jeffrey H Stear; Tim L Noetzel; Jawdat Al-Bassam; Kazuhisa Kinoshita; Stephen C Harrison; Jonathon Howard; Anthony A Hyman
Journal:  Cell       Date:  2008-01-11       Impact factor: 41.582

2.  A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments.

Authors:  Matthew P Miller; Charles L Asbury; Sue Biggins
Journal:  Cell       Date:  2016-05-05       Impact factor: 41.582

3.  RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha.

Authors:  Stefanie Galbán; Yuki Kuwano; Rudolf Pullmann; Jennifer L Martindale; Hyeon Ho Kim; Ashish Lal; Kotb Abdelmohsen; Xiaoling Yang; Youngjun Dang; Jun O Liu; Stephen M Lewis; Martin Holcik; Myriam Gorospe
Journal:  Mol Cell Biol       Date:  2007-10-29       Impact factor: 4.272

Review 4.  Long non-coding RNAs: new players in cell differentiation and development.

Authors:  Alessandro Fatica; Irene Bozzoni
Journal:  Nat Rev Genet       Date:  2013-12-03       Impact factor: 53.242

5.  RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.

Authors:  Krystyna Mazan-Mamczarz; Stefanie Galbán; Isabel López de Silanes; Jennifer L Martindale; Ulus Atasoy; Jack D Keene; Myriam Gorospe
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-23       Impact factor: 12.779

6.  Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.

Authors:  Ivano Legnini; Gaia Di Timoteo; Francesca Rossi; Mariangela Morlando; Francesca Briganti; Olga Sthandier; Alessandro Fatica; Tiziana Santini; Adrian Andronache; Mark Wade; Pietro Laneve; Nikolaus Rajewsky; Irene Bozzoni
Journal:  Mol Cell       Date:  2017-03-23       Impact factor: 17.970

Review 7.  Gene regulation by long non-coding RNAs and its biological functions.

Authors:  Luisa Statello; Chun-Jie Guo; Ling-Ling Chen; Maite Huarte
Journal:  Nat Rev Mol Cell Biol       Date:  2020-12-22       Impact factor: 94.444

8.  Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma.

Authors:  Francesca Rossi; Ivano Legnini; Francesca Megiorni; Alessio Colantoni; Tiziana Santini; Mariangela Morlando; Gaia Di Timoteo; Dario Dattilo; Carlo Dominici; Irene Bozzoni
Journal:  Oncogene       Date:  2019-01-22       Impact factor: 9.867

9.  Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity.

Authors:  Francesca Rossi; Manuel Beltran; Michela Damizia; Chiara Grelloni; Alessio Colantoni; Adriano Setti; Gaia Di Timoteo; Dario Dattilo; Alvaro Centrón-Broco; Carmine Nicoletti; Maurizio Fanciulli; Patrizia Lavia; Irene Bozzoni
Journal:  Mol Cell       Date:  2021-12-22       Impact factor: 17.970
  9 in total

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