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Literature DB >> 3543064

DNA analysis in human disease.

Abstract

The analysis of human DNA using recombinant DNA technology is fast becoming an integral part of the diagnosis, assessment, and prevention of inherited and somatic genetic disease. The rationale underlying these methods of analysis is discussed, and the nature and extent of mutational change in heritable disorders and neoplastic development is outlined.

Entities: Disease Species

Mesh：

Substances：

Year: 1986 PMID： 3543064 PMCID： PMC1140789 DOI： 10.1136/jcp.39.12.1281

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

89 in total

1. Thermal renaturation of deoxyribonucleic acids.

Authors: J MARMUR; P DOTY
Journal: J Mol Biol Date: 1961-10 Impact factor: 5.469

2. Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients.

Authors: T G Krontiris; N A DiMartino; M Colb; D R Parkinson
Journal: Nature Date: 1985 Jan 31-Feb 6 Impact factor: 49.962

3. A multipoint linkage analysis program for X-linked disorders, with the example of Duchenne muscular dystrophy and seven DNA probes.

Authors: J Clayton
Journal: Hum Genet Date: 1986-05 Impact factor: 4.132

4. Reduction in the rate of DNA reassociation by sequence divergence.

Authors: T I Bonner; D J Brenner; B R Neufeld; R J Britten
Journal: J Mol Biol Date: 1973-12-05 Impact factor: 5.469

5. Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

Authors: J Ott
Journal: Am J Hum Genet Date: 1974-09 Impact factor: 11.025

6. Kinetics of renaturation of DNA.

Authors: J G Wetmur; N Davidson
Journal: J Mol Biol Date: 1968-02-14 Impact factor: 5.469

Review 7. The molecular genetics of human hemoglobin.

Authors: F S Collins; S M Weissman
Journal: Prog Nucleic Acid Res Mol Biol Date: 1984

Review 8. The molecular genetics of cellular oncogenes.

Authors: H E Varmus
Journal: Annu Rev Genet Date: 1984 Impact factor: 16.830

9. Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs.

Authors: E Bakker; M H Hofker; N Goor; J L Mandel; K Wrogemann; K E Davies; L M Kunkel; H F Willard; W A Fenton; L Sandkuyl
Journal: Lancet Date: 1985-03-23 Impact factor: 79.321

10. Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome.

Authors: U Francke; H D Ochs; B de Martinville; J Giacalone; V Lindgren; C Distèche; R A Pagon; M H Hofker; G J van Ommen; P L Pearson
Journal: Am J Hum Genet Date: 1985-03 Impact factor: 11.025

1 in total

1. Haemophilia A: carrier detection and prenatal diagnosis by linkage analysis using DNA polymorphism.

Authors: E G Tuddenham; E Goldman; A McGraw; P B Kernoff
Journal: J Clin Pathol Date: 1987-09 Impact factor: 3.411

1 in total