| Literature DB >> 35415480 |
Ryan B Bucknam1,2, John C Dunn2, Isaac Fernandez1, Leon J Nesti3, Gilberto A Gonzalez1.
Abstract
Purpose: Lacerations to the ulnar and median nerve in the volar forearm have demonstrated considerable long-term clinical and socioeconomic impacts on patients. The purpose of this study was to evaluate the outcomes of complex volar forearm lacerations involving one or more major peripheral nerves in an economically disadvantaged patient population.Entities:
Keywords: Nerve laceration; Nerve repair; Return to work; Spaghetti wrist; Volar laceration
Year: 2020 PMID: 35415480 PMCID: PMC8991548 DOI: 10.1016/j.jhsg.2019.12.002
Source DB: PubMed Journal: J Hand Surg Glob Online ISSN: 2589-5141
Patient Demographic Characteristics Stratified According to Nerve Injury Group
| Characteristics | Median Nerve (n = 22) | Ulnar Nerve (n = 27) | Combined Nerve Injury (n = 12) | |
|---|---|---|---|---|
| Age, y (median [interquartile range]) | 35.5 (27.5–40.8) | 29.0 (24.0–36.0) | 23.0 (20.0–31.0) | .04 |
| Gender | ||||
| Male | 14 | 8 | 7 | .26 |
| Female | 8 | 19 | 5 | |
| Mechanism of injury | ||||
| Broken glass | 2 | 15 | 7 | < .01 |
| Motor vehicle Accident | 2 | 2 | 2 | |
| Work accident | 6 | 3 | 1 | |
| Suicide attempt | 12 | 7 | 2 | |
| Occupation | ||||
| Office | 7 | 7 | 0 | .08 |
| Manual labor | 15 | 20 | 12 | |
| Workers’ compensation | ||||
| Yes | 4 | 5 | 2 | .99 |
| No | 18 | 22 | 10 | |
| Time to surgery, h (median [interquartile range]) | 17.5 (13.0–21.5) | 12.0 (8.0–21.50) | 6.0 (4.0–7.0) | < .01 |
| Associated vascular injuries | 10 | 15 | 12 | < .01 |
| Tendons lacerated | Flexor carpi radialis, flexor pollicis longus, palmaris longus | Flexor carpi ulnaris, flexor digitorum profundus, flexordigitorum superficialis | Flexor carpi ulnaris, flexor digitorum profundus, flexor digitorum superficialis, flexor carpi radialis, flexor pollicis longus, palmaris longus | |
| Injury and hand dominance | ||||
| Dominant hand | 17 | 24 | 4 | < .01 |
| Nondominant hand | 5 | 3 | 8 | |
Significant at α = .05.
Superscript letters indicate significant differences between corresponding groups for the given variable on post hoc analysis.
Functional Outcomes Scores and Complications
| Outcomes | 6 Mo | 12 Mo | |||||
|---|---|---|---|---|---|---|---|
| Median Nerve (n = 22) | Ulnar Nerve (n = 27) | Combined Nerve Injury (n = 12) | Median Nerve (n = 22) | Ulnar Nerve (n = 27) | Combined Nerve Injury (n = 12) | ||
| Return to work | |||||||
| Yes | 19 (86%) | 21 (78%) | 4 (33%) | 21 (95%) | 24 (89%) | 9 (75%) | |
| No | 3 (14%) | 6 (22%) | 8 (67%) | 1 (5%) | 3 (11%) | 3 (25%) | |
| Visual analog scale score (median [interquartile range]) | |||||||
| 2.5 (2.0–3.0) | 4.0 (3.0–5.5) | 3.5 (3.0–4.5) | 1.0 (1.0–2.0) | 2.0 (1.5–3.0) | 2.0 (1.8–3.3) | ||
| 49.8 (3.8) | 49.4 (4.2) | 64.4 (2.9) | 29.1 (5.0) | 31.0 (5.6) | 37.9 (2.8) | ||
| Grip strength, lb (median [interquartile range]) | |||||||
| 67.5 (51.3–75.0) | 65.0 (45.0–77.5) | 42.5 (40.0–56.3) | 100.0 (75.0–108.8) | 105.0 (67.5–115.0) | 67.5 (63.8–83.8) | ||
| Pinch strength, lb (median [interquartile range]) | |||||||
| 9.5 (8.3–12.0) | 11.0 (8.0–12.5) | 6.50 (5.8–8.0) | 16.5 (11.0–18.0) | 16.0 (10.0–17.0) | 10.5 (9.0–14.3) | ||
| Medical Research Council sensation (patients) | |||||||
| 2+ (1+ to 3) | 2 (1 to 3) | 1 (1) | 3+ (3 to 4) | 3 (2+ to 4) | 2+ (2 to 3) | ||
| Medical Research Council motor rating | |||||||
| 3 | 2 | 25 | 0 | ||||
| 4 | 20 | 2 | 12 | 2 | 6 | 5 | |
| 4+ | 4 | 8 | 5 | ||||
| 5 | 16 | 13 | 2 | ||||
| 2-Point discrimination rating, mm | |||||||
| 6 | 22 | 0 | 0 | ||||
| 7 | 0 | 26 | 9 | ||||
| 8.5 | 22 | 27 | 12 | 0 | 1 | 3 | |
| Cold sensitivity | |||||||
| Yes | 1 | 3 | 3 | 1 | 1 | 3 | |
| No | 21 | 24 | 9 | 21 | 26 | 9 | |
Significant at α = .05.
Superscript letters indicate significant differences between corresponding groups for the given variable in a given time frame on post hoc analysis.
Functional Outcomes Scores and Complications Based on Workers’ Compensation Status
| Outcomes | 6 Mo | 12 Mo | ||
|---|---|---|---|---|
| Office Job (n = 14) | Manual Laborer (n = 47) | Office Job (n = 14) | Manual Laborer (n = 47) | |
| Return to work | ||||
| Yes | 14 (100%) | 30 (64%) | 14 (100%) | 40 (85%) |
| No | 0 | 17 (36%) | 0 | 7 (15%) |
| Visual analog scale scores (median [interquartile range]) | ||||
| 3.0 (2.0–3.8) | 3.0 (3.0–5.0) | 1.5 (1.0–2.0) | 2.0 (1.0–3.0) | |
| 48.0 (48.0–48.0) | 52.0 (50.0–58.0) | 27.0 (26.0–29.5) | 34.0 (30.0–37.0) | |
| Grip strength, lb (median [interquartile range]) | ||||
| 77.5 (52.8–80.0) | 60.0 (40.0–70.0) | 115.0 (75.0–118.8) | 100 (65.0–105.0) | |
| Pinch strength, lb (median [interquartile range]) | ||||
| 11.0 (8.0–12.0) | 9.0 (7.0–12.0) | 17.5 (10.3–19.0) | 15.0 (10.0–17.0) | |
| Medical Research Council sensation rating | ||||
| 1 | 0 | 12 | ||
| 2 | 7 | 15 | ||
| 2.5 | 7 | 20 | 0 | 12 |
| 3 | 7 | 15 | ||
| 3.5 | 7 | 20 | ||
| Medical Research Council motor rating | ||||
| 3 | 6 | 21 | ||
| 4 | 8 | 26 | 0 | 13 |
| 4+ | 1 | 16 | ||
| 5 | 13 | 18 | ||
| 2-Point discrimination, mm | ||||
| 6 | 7 | 20 | ||
| 7 | 7 | 23 | ||
| 8.5 | 11 | 47 | 0 | 4 |
| Cold sensitivity | ||||
| Yes | 0 | 7 | 0 | 5 |
| No | 14 | 40 | 14 | 42 |
Significant at α = .05.
Functional Outcomes Scores and Complications Based on Injured Extremity
| Outcomes | 6 Mo | 12 Mo | ||
|---|---|---|---|---|
| Dominant Hand (n = 45) | Nondominant Hand (n = 16) | Dominant Hand (n = 45) | Nondominant Hand (n = 16) | |
| Return to work | ||||
| Yes | 33 (73%) | 11 (69%) | 38 (84%) | 16 (100%) |
| No | 12 (27%) | 5 (31%) | 7 (16%) | 0 |
| Visual analog scale scores (median [interquartile range]) | ||||
| 3.0 (2.0–5.0) | 3.0 (2.8–3.3) | 2.0 (1.0–3.0) | 2.0 (1.0–2.0) | |
| 50.0 (48.0–52.0) | 58.0 (50.0–62.5) | 30.9 (5.9) | 33.8 (5.4) | |
| Grip strength, lb (median [interquartile range]) | ||||
| 65.0 (55.0–75.0) | 45.0 (40.0–55.3) | 100.0 (75.0–115.0) | 70.0 (65.0–82.5) | |
| Pinch strength, lb (median [interquartile range]) | ||||
| 10.0 (8.0–12.0) | 7.5 (5.8–8.0) | 16.0 (12.0–18.0) | 10.0 (9.0–12.5) | |
| Medical Research Council sensation rating | ||||
| 1 | 4 | 8 | ||
| 2 | 17 | 15 | ||
| 2.5 | 24 | 3 | 4 | 8 |
| 3 | 17 | 15 | ||
| 3.5 | 24 | 3 | ||
| Medical Research Council motor rating | ||||
| 3 | 24 | 3 | ||
| 4 | 21 | 13 | 10 | 3 |
| 4+ | 12 | 5 | ||
| 5 | 23 | 8 | ||
| 2-Point discrimination, mm | ||||
| 6 | 24 | 3 | ||
| 7 | 17 | 13 | ||
| 8.5 | 45 | 16 | 4 | 0 |
| Cold sensitivity | ||||
| Yes | 7 | 0 | 5 | 0 |
| No | 38 | 16 | 40 | 16 |
Significant at α = .05.
Study Findings and Comparison With Other Literature†
| Study | Patients, n | Nerves | Age, years | Follow-Up, years | Outcomes |
|---|---|---|---|---|---|
| Flynn and Flynn, | 80 | M (40) | 28.75 (15–55) | (1–12) | Sensation: no difference between U (20%) and M (20%) |
| Jaquet et al, | 220 | M (105) | 31.4 (5–73) | 1.48 (0.1–14.4) | Sensation: no significant difference between U (59% recovery), M (62%), MU (55%)—MU with worse recovery than U or M |
| Ruijs et al, | 623 | M (253) | Sensation: no significant difference between M (44%), U (41%), or MU (41%) | ||
| Bruyns et al, | 81 | M (30) | 30.5 (18–58) | RTW: highest for M (80%), then U (59%), lowest for MU (24%) by 1 y | |
| Vordemvenne et al, | 71 | M (35) | 28.4 (2–69) | Sensation: no significant difference between U (20% recovery) and M (40%) | |
| Kilinc et al, | 39 (40 nerves) | M (20) | 28 (12–45) | 1.9 (1-4.5) | Sensation: U (71% recovery); M (50%); MU (15%) |
| Galanakos et al, | 73 | M (25) | 31 (14–62) | 3 (2–6) | Sensation: Improvement between M (96% recovery), U (96.3%), MU (71.4%) |
| Galanakos et al, | 73 | M (25) | 31 (14–62) | 3 (2–6) | RTW: MU (52.3%), vs M (96%) or U (96.3%) |
| Hundepool et al, | 61 | M (28) | 1 | Sensation: Regression model identified negative predictive factors for recovery of sensation: male gender, older age, and combined nerve injuries | |
| Current findings | 61 | M (22) | 31 (18–45) | 1 | Sensation: M (100%), U (100%), and MU (0%) at 12 mo; no significant difference between manual laborers (50%) and office workers (43%) at 1 y |
| Aggregate | 1,383 | M (588) | 30.4 (2–78) | 1.82 (0.1–14.4) | Sensation: M, 51% (254 of 500); U, 48% (209 of 433); MU, 43% (97 of 227) |
M, median nerve injury; MU, combined median and ulnar injury; RTW, return to work; TOW, time off work; U, ulnar nerve injury.
Statistically significant difference.
Sensory recovery was defined as ≥ S3+ at last follow-up; motor recovery was defined as a Medical Research Council score of ≥ 4 at last follow up. Ranges are presented in brackets.