Esophageal optical coherence tomography image synthesis using an adversarially learned variational autoencoder.

Endoscopic optical coherence tomography (OCT) imaging offers a non-invasive way to detect esophageal lesions on the microscopic scale, which is of clinical potential in the early diagnosis and treatment of esophageal cancers. Recent studies focused on applying deep learning-based methods in esophageal OCT image analysis and achieved promising results, which require a large data size. However, traditional data augmentation techniques generate samples that are highly correlated and sometimes far from reality, which may not lead to a satisfied trained model. In this paper, we proposed an adversarial learned variational autoencoder (AL-VAE) to generate high-quality esophageal OCT samples. The AL-VAE combines the generative adversarial network (GAN) and variational autoencoder (VAE) in a simple yet effective way, which preserves the advantages of VAEs, such as stable training and nice latent manifold, and requires no extra discriminators. Experimental results verified the proposed method achieved better image quality in generating esophageal OCT images when compared with the state-of-the-art image synthesis network, and its potential in improving deep learning model performance was also evaluated by esophagus segmentation.