Literature DB >> 35399320

Multimodal Evaluation of Voice Outcome in Early Glottic Cancers Treated With Definitive Radiotherapy.

Marianna Trignani1, Angelo DI Pilla1, Consuelo Rosa1,2, Marzia Borgia1, David Fasciolo1, Lucrezia Gasparini1, Fiorella DI Guglielmo1, Albina Allajbej1, Marta DI Francesco3, Gianluca Falcone3, Francesca Vitullo4, Adelchi Croce4, Domenico Genovesi1,2, Luciana Caravatta1.   

Abstract

Background/Aim: We employed a multimodal evaluation of voice outcome (MEVO) model to assess long-term voice outcome in early glottic cancer (EGC) patients treated with primary radiotherapy (RT). The model consisted of objective and subjective vocal evaluation during follow-up, by a dedicated Speech Pathologist and Speech Therapist. Patients and
Methods: MEVO methodology includes Self-perception Voice Handicap Index (VHI-30), evaluation of parameters Grade (G), Roughness (R), Breathiness (B), Asthenia (A) and Strain (S) according to GRBAS scale, objective analysis and aerodynamics using the PRAAT software and laryngeal evaluation with videostroboscope (VS).
Results: The MEVO methodology was described and tested on a sample of 10 EGCs submitted to definitive RT (total dose 66-70 Gy). Mean follow-up was 48.9 months (range=9-115). VHI was mild-moderate in 90% of patients; overall voice function (GRBAS) was normal-mildly impaired in 70% of patients; VS evaluation showed normal vocal cord motion in 90% of patients, but complete glottic closure in 60%. PRAAT scores confirmed these findings.
Conclusion: A multidimensional voice evaluation is time consuming, but useful to objectify vocal impact of radiotherapy. The MEVO model allowed to quantify vocal dysfunction, showing a good objective vocal outcome. Copyright 2021, International Institute of Anticancer Research.

Entities:  

Keywords:  Early glottic cancer; multidimensional assessment; multidisciplinary team; radiotherapy; voice outcome

Year:  2021        PMID: 35399320      PMCID: PMC8962787          DOI: 10.21873/cdp.10019

Source DB:  PubMed          Journal:  Cancer Diagn Progn        ISSN: 2732-7787


  29 in total

1.  A basic protocol for functional assessment of voice pathology, especially for investigating the efficacy of (phonosurgical) treatments and evaluating new assessment techniques. Guideline elaborated by the Committee on Phoniatrics of the European Laryngological Society (ELS).

Authors:  P H Dejonckere; P Bradley; P Clemente; G Cornut; L Crevier-Buchman; G Friedrich; P Van De Heyning; M Remacle; V Woisard
Journal:  Eur Arch Otorhinolaryngol       Date:  2001-02       Impact factor: 2.503

Review 2.  Voice outcomes following radiation versus laser microsurgery for T1 glottic carcinoma: systematic review and meta-analysis.

Authors:  Matthew T Greulich; Noah P Parker; Philip Lee; Albert L Merati; Stephanie Misono
Journal:  Otolaryngol Head Neck Surg       Date:  2015-04-02       Impact factor: 3.497

3.  Voice quality after treatment of early glottic carcinoma.

Authors:  Ana Jotic; Predrag Stankovic; Snezana Jesic; Jovica Milovanovic; Milena Stojanovic; Vojko Djukic
Journal:  J Voice       Date:  2011-08-12       Impact factor: 2.009

4.  Comparison of voice quality after laser cordectomy with that after radiotherapy or chemoradiotherapy for early glottic carcinoma.

Authors:  Masayuki Tomifuji; Koji Araki; Katsuki Niwa; Yoshihiro Miyagawa; Daisuke Mizokami; Yoko Kitagawa; Taku Yamashita; Takeshi Matsunobu; Akihiro Shiotani
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  2013-03-20       Impact factor: 1.538

Review 5.  "Early" cancer of the larynx: the concept as defined by clinicians, pathologists, and biologists.

Authors:  A Ferlito; A Carbone; A Rinaldo; A Ferlito; L W DeSanto; L D'Angelo; L Barnes; K O Devaney
Journal:  Ann Otol Rhinol Laryngol       Date:  1996-03       Impact factor: 1.547

6.  Exclusive Radiotherapy for Early-stage Glottic Cancer: A Single-institution Retrospective Analysis with a Focus on Voice Quality.

Authors:  Ilenia Potenza; Pierfrancesco Franco; Francesco Moretto; Serena Badellino; Vittoria Balcet; Giuseppe Rossi; Vincenzo Landolfo; Giuseppe Riva; Giancarlo Pecorari; Riccardo Ragona; Monica Rampino; Umberto Ricardi
Journal:  Anticancer Res       Date:  2015-07       Impact factor: 2.480

Review 7.  Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer.

Authors:  Laura Warner; Jessal Chudasama; Charles G Kelly; Sean Loughran; Kenneth McKenzie; Richard Wight; Paola Dey
Journal:  Cochrane Database Syst Rev       Date:  2014-12-12

8.  Voice outcome in T1a midcord glottic carcinoma: laser surgery vs radiotherapy.

Authors:  Elisabeth V Sjögren; Maya A van Rossum; Ton P M Langeveld; Marika S Voerman; Vivienne A H van de Kamp; Mark O W Friebel; Ron Wolterbeek; Robert J Baatenburg de Jong
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2008-09

9.  Voice quality after treatment of early vocal cord cancer: a randomized trial comparing laser surgery with radiation therapy.

Authors:  Leena-Maija Aaltonen; Noora Rautiainen; Jaana Sellman; Kauko Saarilahti; Antti Mäkitie; Heikki Rihkanen; Jussi Laranne; Leenamaija Kleemola; Tuija Wigren; Eeva Sala; Paula Lindholm; Reidar Grenman; Heikki Joensuu
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-10-01       Impact factor: 7.038

Review 10.  Evidence-based clinical voice assessment: a systematic review.

Authors:  Nelson Roy; Julie Barkmeier-Kraemer; Tanya Eadie; M Preeti Sivasankar; Daryush Mehta; Diane Paul; Robert Hillman
Journal:  Am J Speech Lang Pathol       Date:  2012-11-26       Impact factor: 2.408

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  1 in total

1.  Smile InTM Totems in Radiotherapy: Patients' Satisfaction with Limited Equipment and COVID-19.

Authors:  Marzia Borgia; Fiorella Cristina Di Guglielmo; Marco Lucarelli; Rosario Bonelli; Lucrezia Gasparini; Angelo Di Pilla; Lucia Anna Ursini; Maria Taraborrelli; Annamaria Vinciguerra; Antonietta Augurio; Monica Di Tommaso; Marianna Trignani; Marianna Nuzzo; Consuelo Rosa; Giuditta Chiloiro; Stephanie Sartori; Lucia Ferrari; Roberta Marchione; Fabio Adalgiso D'Orazio; Paola Di Renzo; Giustino Orlando; Domenico Genovesi; Luciana Caravatta
Journal:  Healthcare (Basel)       Date:  2022-08-13
  1 in total

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