| Literature DB >> 35390131 |
Patricia Stewart1, Caroline P Groth2, Tran B Huynh3, Melanie Gorman Ng4, Gregory C Pratt5, Susan F Arnold5, Gurumurthy Ramachandran6,7, Sudipto Banerjee7, John W Cherrie8, Kate Christenbury9, Richard K Kwok10,11, Aaron Blair12, Lawrence S Engel10,13, Dale P Sandler10, Mark R Stenzel14.
Abstract
The GuLF Study is investigating adverse health effects from work on the response and clean-up after the Deepwater Horizon explosion and oil release. An essential and necessary component of that study was the exposure assessment. Bayesian statistical methods and over 135 000 measurements of total hydrocarbons (THC), benzene, ethylbenzene, toluene, xylene, and n-hexane (BTEX-H) were used to estimate inhalation exposures to these chemicals for >3400 exposure groups (EGs) formed from three exposure determinants: job/activity/task, location, and time period. Recognized deterministic models were used to estimate airborne exposures to particulate matter sized 2.5 µm or less (PM2.5) and dispersant aerosols and vapors. Dermal exposures were estimated for these same oil-related substances using a model modified especially for this study from a previously published model. Exposures to oil mist were assessed using professional judgment. Estimated daily THC arithmetic means (AMs) were in the low ppm range (<25 ppm), whereas BTEX-H exposures estimates were generally <1000 ppb. Potential 1-h PM2.5 air concentrations experienced by some workers may have been as high as 550 µg m-3. Dispersant aerosol air concentrations were very low (maximum predicted 1-h concentrations were generally <50 µg m-3), but vapor concentrations may have exceeded occupational exposure excursion guidelines for 2-butoxyethanol under certain circumstances. The daily AMs of dermal exposure estimates showed large contrasts among the study participants. The estimates are being used to evaluate exposure-response relationships in the GuLF Study. Published by Oxford University Press on behalf of The British Occupational Hygiene Society 2022.Entities:
Keywords: zzm321990 Deepwater Horizonzzm321990 ; PM2.5; dispersant; exposure assessment; total hydrocarbons
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Year: 2022 PMID: 35390131 PMCID: PMC8989041 DOI: 10.1093/annweh/wxab107
Source DB: PubMed Journal: Ann Work Expo Health ISSN: 2398-7308 Impact factor: 2.779