Literature DB >> 35383328

Could computer models be the key to better COVID vaccines?

Elie Dolgin.   

Abstract

Entities:  

Keywords:  Public health; SARS-CoV-2; Vaccines

Mesh：

Substances：

Year:  2022        PMID： 35383328     DOI： 10.1038/d41586-022-00924-8

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  10 in total

1.  mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials.

Authors:  Robert A Feldman; Rainard Fuhr; Igor Smolenov; Amilcar Mick Ribeiro; Lori Panther; Mike Watson; Joseph J Senn; Mike Smith; Ӧrn Almarsson; Hari S Pujar; Michael E Laska; James Thompson; Tal Zaks; Giuseppe Ciaramella
Journal:  Vaccine       Date:  2019-05-10       Impact factor: 3.641

2.  A virtual host model of Mycobacterium tuberculosis infection identifies early immune events as predictive of infection outcomes.

Authors:  Louis R Joslyn; Jennifer J Linderman; Denise E Kirschner
Journal:  J Theor Biol       Date:  2022-01-31       Impact factor: 2.405

3.  Dose finding for new vaccines: The role for immunostimulation/immunodynamic modelling.

Authors:  Sophie J Rhodes; Gwenan M Knight; Denise E Kirschner; Richard G White; Thomas G Evans
Journal:  J Theor Biol       Date:  2019-01-10       Impact factor: 2.691

4.  A preliminary report of a randomized controlled phase 2 trial of the safety and immunogenicity of mRNA-1273 SARS-CoV-2 vaccine.

Authors:  Laurence Chu; Roderick McPhee; Wenmei Huang; Hamilton Bennett; Rolando Pajon; Biliana Nestorova; Brett Leav
Journal:  Vaccine       Date:  2021-02-09       Impact factor: 3.641

5.  Optimising Vaccine Dose in Inoculation against SARS-CoV-2, a Multi-Factor Optimisation Modelling Study to Maximise Vaccine Safety and Efficacy.

Authors:  John Benest; Sophie Rhodes; Matthew Quaife; Thomas G Evans; Richard G White
Journal:  Vaccines (Basel)       Date:  2021-01-22

6.  A quantitative systems pharmacology approach to support mRNA vaccine development and optimization.

Authors:  Gianluca Selvaggio; Lorena Leonardelli; Giuseppe Lofano; Stephanie Fresnay; Silivia Parolo; Duccio Medini; Emilio Siena; Luca Marchetti
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2021-10-21

7.  Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making.

Authors:  Sophie J Rhodes; Jeremie Guedj; Helen A Fletcher; Thomas Lindenstrøm; Thomas J Scriba; Thomas G Evans; Gwenan M Knight; Richard G White
Journal:  NPJ Vaccines       Date:  2018-09-17       Impact factor: 7.344

8.  SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

Authors:  Kizzmekia S Corbett; Darin K Edwards; Sarah R Leist; Olubukola M Abiona; Seyhan Boyoglu-Barnum; Rebecca A Gillespie; Sunny Himansu; Alexandra Schäfer; Cynthia T Ziwawo; Anthony T DiPiazza; Kenneth H Dinnon; Sayda M Elbashir; Christine A Shaw; Angela Woods; Ethan J Fritch; David R Martinez; Kevin W Bock; Mahnaz Minai; Bianca M Nagata; Geoffrey B Hutchinson; Kai Wu; Carole Henry; Kapil Bahl; Dario Garcia-Dominguez; LingZhi Ma; Isabella Renzi; Wing-Pui Kong; Stephen D Schmidt; Lingshu Wang; Yi Zhang; Emily Phung; Lauren A Chang; Rebecca J Loomis; Nedim Emil Altaras; Elisabeth Narayanan; Mihir Metkar; Vlad Presnyak; Cuiping Liu; Mark K Louder; Wei Shi; Kwanyee Leung; Eun Sung Yang; Ande West; Kendra L Gully; Laura J Stevens; Nianshuang Wang; Daniel Wrapp; Nicole A Doria-Rose; Guillaume Stewart-Jones; Hamilton Bennett; Gabriela S Alvarado; Martha C Nason; Tracy J Ruckwardt; Jason S McLellan; Mark R Denison; James D Chappell; Ian N Moore; Kaitlyn M Morabito; John R Mascola; Ralph S Baric; Andrea Carfi; Barney S Graham
Journal:  Nature       Date:  2020-08-05       Impact factor: 49.962

9.  Application of quantitative systems pharmacology to guide the optimal dosing of COVID-19 vaccines.

Authors:  Mario Giorgi; Rajat Desikan; Piet H van der Graaf; Andrzej M Kierzek
Journal:  CPT Pharmacometrics Syst Pharmacol       Date:  2021-08-12

10.  Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans.

Authors:  Barbra A Dickerman; Hanna Gerlovin; Arin L Madenci; Katherine E Kurgansky; Brian R Ferolito; Michael J Figueroa Muñiz; David R Gagnon; J Michael Gaziano; Kelly Cho; Juan P Casas; Miguel A Hernán
Journal:  N Engl J Med       Date:  2021-12-01       Impact factor: 91.245
  10 in total

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