| Literature DB >> 35381337 |
Yibin Zhang1, Dilka Liyana Arachchige2, Adenike Olowolagba2, Rudy L Luck3, Haiying Liu4.
Abstract
A near-infrared fluorescent probe was prepared for selective detection of reduced nicotinamide adenine dinucleotide (NADH) in live cells. The probe turns off the fluorescence with a closed spironolactone switch. However, reduction of the probe by NADH turns on fluorescence at 740 nm. Theoretical calculations suggest a more planar arrangement between the rhodamine and quinoline moieties with increased π-delocalization resulting from reduction.Entities:
Keywords: Cellular Imaging; Computation chemistry; NADH; Near-infrared fluorescent probe
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Year: 2022 PMID： 35381337 PMCID： PMC9233151 DOI： 10.1016/j.ymeth.2022.03.019
Source DB: PubMed Journal: Methods ISSN： 1046-2023 Impact factor: 4.647