Literature DB >> 3537699

Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene.

D J Thiele, D H Hamer.   

Abstract

Transcription of the Saccharomyces cerevisiae copper-metallothionein gene, CUP1, inducible by copper. By analyzing deletion and fusion mutants in the CUP1 5'-flanking region, we identified two closely related, tandemly arranged copper regulatory elements. A synthetic version of one of these elements conferred efficient copper induction on a heterologous promoter when present in two tandem copies.

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Year:  1986        PMID： 3537699      PMCID： PMC367627          DOI： 10.1128/mcb.6.4.1158-1163.1986

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  22 in total

1.  A short nucleotide sequence required for regulation of HIS4 by the general control system of yeast.

Authors:  T F Donahue; R S Daves; G Lucchini; G R Fink
Journal:  Cell       Date:  1983-01       Impact factor: 41.582

2.  Tandem gene amplification mediates copper resistance in yeast.

Authors:  S Fogel; J W Welch
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

3.  New M13 vectors for cloning.

Authors:  J Messing
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

4.  Yeast metallothionein. Sequence and metal-binding properties.

Authors:  D R Winge; K B Nielson; W R Gray; D H Hamer
Journal:  J Biol Chem       Date:  1985-11-25       Impact factor: 5.157

5.  Primary structure and transcription of an amplified genetic locus: the CUP1 locus of yeast.

Authors:  M Karin; R Najarian; A Haslinger; P Valenzuela; J Welch; S Fogel
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

6.  Industrial yeasts display tandem gene iteration at the CUP1 region.

Authors:  J W Welch; S Fogel; G Cathala; M Karin
Journal:  Mol Cell Biol       Date:  1983-08       Impact factor: 4.272

7.  The expression in yeast of the Escherichia coli galK gene on CYC1::galK fusion plasmids.

Authors:  B C Rymond; R S Zitomer; D Schümperli; M Rosenberg
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae.

Authors:  L Guarente; B Lalonde; P Gifford; E Alani
Journal:  Cell       Date:  1984-02       Impact factor: 41.582

10.  Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site.

Authors:  L Guarente; T Mason
Journal:  Cell       Date:  1983-04       Impact factor: 41.582
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  52 in total

1.  The CUP1 upstream repeated element renders CUP1 promoter activation insensitive to mutations in the RNA polymerase II transcription complex.

Authors:  Laura Badi; Alcide Barberis
Journal:  Nucleic Acids Res       Date:  2002-03-15       Impact factor: 16.971

2.  The DAL7 promoter consists of multiple elements that cooperatively mediate regulation of the gene's expression.

Authors:  H S Yoo; T G Cooper
Journal:  Mol Cell Biol       Date:  1989-08       Impact factor: 4.272

3.  The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae.

Authors:  Yelena V Budovskaya; Joseph S Stephan; Fulvio Reggiori; Daniel J Klionsky; Paul K Herman
Journal:  J Biol Chem       Date:  2004-03-11       Impact factor: 5.157

Review 4.  Metal-responsive transcription factors that regulate iron, zinc, and copper homeostasis in eukaryotic cells.

Authors:  Julian C Rutherford; Amanda J Bird
Journal:  Eukaryot Cell       Date:  2004-02

5.  Multiple positive and negative cis-acting elements mediate induced arginase (CAR1) gene expression in Saccharomyces cerevisiae.

Authors:  L Kovari; R Sumrada; I Kovari; T G Cooper
Journal:  Mol Cell Biol       Date:  1990-10       Impact factor: 4.272

6.  Transcriptional activation by upstream activator sequences requires distinct interactions with downstream elements in the yeast TRP1 promoter.

Authors:  J Mellor; C Midgely; A J Kingsman; S M Kingsman; S Kim
Journal:  Mol Gen Genet       Date:  1991-02

7.  Isolation of a metal-activated transcription factor gene from Candida glabrata by complementation in Saccharomyces cerevisiae.

Authors:  P B Zhou; D J Thiele
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

8.  Cooperative activation of a eukaryotic transcription factor: interaction between Cu(I) and yeast ACE1 protein.

Authors:  P Fürst; D Hamer
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

9.  Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast.

Authors:  J B McNeil; H Agah; D Bentley
Journal:  Genes Dev       Date:  1998-08-15       Impact factor: 11.361

10.  PAK1, a gene that can regulate p53 activity in yeast.

Authors:  S Thiagalingam; K W Kinzler; B Vogelstein
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205
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