| Literature DB >> 35366502 |
Kelly C Y Wong1, Ellen M Sletten2.
Abstract
Fluorescence imaging is an indispensable method for studying biological processes non-invasively in cells and transparent organisms. Extension into the shortwave infrared (SWIR, 1000-2000 nm) region of the electromagnetic spectrum has allowed for imaging in mammals with unprecedented depth and resolution for optical imaging. In this review, we summarize recent advances in imaging technologies, dye scaffold modifications, and incorporation of these dyes into probes for SWIR imaging in mice. Finally, we offer an outlook on the future of SWIR detection in the field of chemical biology.Entities:
Keywords: Confocal microscopy; Fluorogenic probe; Fluorophore; Light-sheet microscopy; Molecular imaging; Multicolor imaging; Multiplexed imaging; Ratiometric probe; Shortwave infrared; Small molecule dye; Targeted imaging
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Year: 2022 PMID： 35366502 PMCID： PMC9583727 DOI： 10.1016/j.cbpa.2022.102131
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.972